What do the different colour intros mean?

As per the Fringe Wikia article on the opening sequence, each color indicates a different
setting and the words mentioned throughout the title sequence are the particular areas of
science that will be looked at during that episode and/or series of episodes sharing an
introduction. In addition to this, the text "Observers are here" flashes during every opening
sequence except for episodes using the observers opening sequence.
The blue opening sequence is used for every episode in Season 1 and 2 except "Peter",
"Over There", and most episodes in season 3. A blue title sequence indicates that the
episode takes place in the prime universe.

The red opening sequence is used for the final episodes of season two and episodes in
season three. The red sequence indicates that the episode takes place in the alternate
universe.
There is also a red/blue opening sequence indicating that part of the episode takes place in
each universe.

The amber/yellow opening sequence was used during season four and indicated that the
episode took place during an alternate time line.

The "retro" sequence used in Peter and Subject 13 indicates the episode takes place in
1985.
There was also a black and white/monochrome opening sequence used for a single
episode - The Day We Died, signalling a dying world in the year 2036.

The Observers opening sequence was used in the episode Letters of Transit and every
episode from season five.
In addition to the color of the title sequences, there are also a variety of different fringe
sciences mentioned over the title sequence, depending on the season you're watching. For
season five, these are not sciences but more... fundamental aspects of being human.

Season One: Psychokineses, Teleportation, Nanotechnology, Artificial Intelligence,

Precognition, Dark Matter, Cybernetics, Suspended Animation, Transmogrification
Season Two: Hypnosis, Pyrokinesis, Hive Mind, ESP, Neuroscience, Clairaudience,
Cryonics, Parallel Universes, Astral Projection, Protoscience, Mutation, Genetic Engineering
Episodes using the Retro introduction: Personal Computing, Cold Fusion, Cloning, DNA
Profiling, Nanotechnology, Invisibility, Genetic Engineering, Laser Surgery, Stealth
Technology, In Vitro Fertilization, Virtual Reality
Season Three: Wormholes, Singularity, Speciation, Synesthesia, Transhumanism,
Pandemic, Reanimation, Neural Networks, Telepathy, Transcendence, Retrocognition,
Biotechnology
The Day We Died introduction: Cellular Rejuvenation, Thought Extraction, Cryptozoology,
Neural Partitioning, Brain Porting, Temporal Plasticity, Dual Maternity, Chaos Structure,
Clonal Transplantation, Water, Biosuspension, Hope
Season Four: Existence, Quantum Entanglement, Philosopher's Stone, Psychometry, Viral
Therapy, Ethereal Plane, Gravitons, Time Paradox, Psychogenesis, Bilocation, Psychic
Surgery, Transgenics
Season Five: Community, Joy, Individuality, Education, Imagination, Private Thought, Due
Process, Ownership, Free Will, Freedom

Colors Edit
The color of each Opening Sequence represents a different setting.

The different colours of the Fringe opening sequence.

Blue  Edit

The Blue Opening Sequence is used in every episode from Season One, every episode from Season
Two except for "Peter," "Over There: Part 1," and "Over There: Part 2," and most episodes in Season
Three. Episodes with a blue Opening Sequence take place in the Prime Universe.

Retro Edit

The Retro Opening Sequence is used in Peter and Subject 13. It signals that the episode takes place in
1985.

Red Edit

The Red Opening Sequence is used in the final two episodes of Season Two and several episodes
in Season Three. Episodes contaning a Red Opening Sequence take place in the Alternate Universe.

Blue/Red Edit

The Opening Sequence of Entrada changed between blue and red colors. This represents how the
episode's narrative shifted constantly between the Prime Universe and Alternate Universe.

Monochrome Edit

The Monochrome Opening Sequence was used in The Day We Died. It signaled a bleak, dying Earth in
the year 2026.

Amber Edit

The Amber Opening Sequence was used during every Season Four episode except for Letters of Transit.
It signaled the Alternate Timeline.

Observers Edit
The Observers Opening Sequence depicts a dystopian future with barbed wire fences and other prison-
type images. It signals that the episode takes place in 2036. It is used in Letters of Transit and every
episode from Season Five.

Fringe Sciences Edit

Some of the Fringe sciences in the opening sequence.

Each season has different Fringe Sciences in its opening sequence except for Peter, Subject 13, and The
Day We Died.

Season 1 Edit

Psychokinesis, Teleportation, Nanotechnology, Artificial Intelligence, Precognition, Dark Matter,

Cybernetics, Suspended Animation, Transmogrification

Season 2 Edit

Hypnosis, Pyrokinesis, Hive Mind, ESP, Neuroscience, Clairaudience, Cryonics, Parallel Universes, Astral
Projection, Protoscience, Mutation, Genetic Engineering

Retro Edit

Personal Computing, Cold Fusion, Cloning, DNA Profiling, Nanotechnology, Invisibility, Genetic
Engineering, Laser Surgery, Stealth Technology, In Vitro Fertilization, Virtual Reality

Season 3 Edit

Wormholes, Singularity, Speciation, Synesthesia, Transhumanism, Pandemic, Reanimation, Neural

Networks, Telepathy, Transcendence, Retrocognition, Biotechnology

Monochrome Edit

Cellular Rejuvenation, Thought Extraction, Cryptozoology, Neural Partitioning, Brain Porting, Temporal
Plasticity, Dual Maternity, Chaos Structure, Clonal Transplantation, Water, Biosuspension, Hope

Season 4 Edit

Existence, Quantum Entanglement, Philosopher's Stone, Psychometry, Viral Therapy, Ethereal Plane,
Gravitons, Time Paradox, Psychogenesis, Bilocation, Psychic Surgery, Transgenics
Season 5 Edit

Community, Joy, Individuality, Education, Imagination, Private Thought, Due Process, Ownership, Free
Will, Freedom