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crystalline powder that is slightly soluble in alcohol and practically

insoluble in water. Metronidazole benzoate should be stored in well-


closed, light-resistant containers at room temperature. Metronidazole
benzoate is used as an antibiotic.1

Polyethylene oxide (Polyox, WSR-301) is a nonionic homopolymer of


ethylene oxide, represented by the formula [(OCH2CH2)n], in
which n represents the average number of oxyethylene groups and
varies from about 2,000 to 100,000; the molecular weights range from
about 100,000 to 7 million. Polyethylene oxide occurs as a white to off-
white, free-flowing powder, with a slight odor of ammonia. It is available
in several different grades that vary in viscosity profiles in aqueous
isopropyl alcohol solutions. Polyethylene oxide may contain a suitable
antioxidant. It should be preserved in tight, light-resistant containers.
Polyethylene oxide should be labeled to indicate its viscosity profile,
along with the name and quantity of any added antioxidant. Polyethylene
oxide strongly bonds with water, is nonionic, and undergoes salting-out
effects. All grades of molecular weight occur as powdered or granular
solids that are soluble in water, but because of the high solution
viscosities obtained, solutions greater than 1% in water may be difficult
to prepare. Twenty percent aqueous concentrations form gels that are
nontacky and reversible. Polyethylene oxide is also freely sol

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