AMOXICILLIN

INDICATIONS,
Drug Name/Dosage/ CLASSIFICATION/ NURSING CONSIDERATIONS IN
CONTRAINDICATION AND SIDE EFFECTS AND ADVERSE
Route /Frequency/ MECHANISM OF SIGNIFICANT OTHER AND
DRUG TO DRUG EFFECTS
Drug Order ACTION PATIENT
INTERACTION
Generic Name: Drug Class Indications: SIDE EFFECT Before:
Amoxicillin Pharmacologic class:  Treatment of skin,  agitation  Check and Verify Doctor’s order
Aminopenicillin respiratory, GI, GU  confusion regarding the medication.
Brand Name: infections, otitis  dizziness  Culture and sensitivity before
Ambimox Therapeutic class: media,gonorrhea; for  insomnia product therapy; product may be
Anti-infective gram-positive cocci  nausea given as soon as culture is taken.
Usual Contraindications:  vomiting  Make sure to skin test the client
Dosage/Frequency: Drug Action:  Hypersensitivity to drug or  diarrhea before administering the
500 mg TID Inhibits cell-wall any penicillin medication.
synthesis during bac-
Usual Route ADVERSE EFFECT  Check the MAR and follow the 10
terial multiplication, Drug to Drug Interaction:
Per Orem leading to cell death.  seizures (with high doses) rights for administering medication.
Increase: rash—allopurinol
 pseudomembranous colitis  Make a medication card with the
Increase: amoxicillin level—
Drug Order:  bone marrow depression complete doctor’s order, name of
probenecid; used for this reason
Amoxicillin 500mg Peak of Action: Increase: anticoagulant action—  hemolytic anemia the patient, bed number and room
x1 tab PO TID as 1-2 hr warfarin  overgrowth of infection or ward.
ordered. Increase: methotrexate levels—  Ask the clients full name to verify
Onset of Action:
methotrexate; monitor for toxicity its identity
30 min
Decrease: contraceptive effect  Educate and explain the medication
possible— hormonal contraceptives to the client, how it works, why it is
Duration:
given to her and the possible side
8-12 hr
effect.
Reference: Comerford,  Remind to take without regard to
K. C., & Durkin, M. T. food, that caps may be opened,
(2020). Nursing 2020 contents taken with fluids; that
drug handbook (Vol. 1 & chewable form is available; to take
2). Philadelphia: Wolters as prescribed and not to double
Kluwer dose.
 Tell patient taking hormonal
contraceptives, that drug may
reduce contraceptive efficacy.
Reference: Comerford, K. C., & Durkin, M. T. (2020). Nursing 2020 drug handbook (Vol. 1 & 2). Philadelphia: Wolters Kluwer
 Suggest she use alternative birth
control method.
During
 Tell patient not to chew or swallow
tablets for suspension, because
they’re not meant to be dissolved in
mouth.
 Advise patient to minimize GI upset
by eating small, frequent servings
of food and drinking plenty of
fluids.
 Monitor for signs and symptoms of
hypersensitivity reaction.
 Monitor patient’s temperature and
watch for other signs and
symptoms of superinfection.

After
 Remind patient to complete entire
course of medication to ensure
organism death; that culture may
be taken after completed course of
medication.
 Remind client to report sore throat,
fever, fatigue, diarrhea, blood in
stool, abdominal pain.
 Tell patient that product must be
taken in equal intervals around the
clock to maintain blood levels.
 Inform patient that drug lowers
resistance to other types of
infections. Instruct her to report
new signs and symptoms of
infection, especially in mouth or
rectum.
 Document the important details

Reference: Comerford, K. C., & Durkin, M. T. (2020). Nursing 2020 drug handbook (Vol. 1 & 2). Philadelphia: Wolters Kluwer
 regarding the medication
administration. This includes the
date, time, reaction to drug and
effect.

MEFENAMIC ACID
INDICATIONS,
Drug Name/Dosage/ CLASSIFICATION/ NURSING CONSIDERATIONS IN
CONTRAINDICATION AND SIDE EFFECTS AND ADVERSE
Route /Frequency/ MECHANISM OF SIGNIFICANT OTHER AND
DRUG TO DRUG EFFECTS
Drug Order ACTION PATIENT
INTERACTION
Generic Name: Drug Class Indications: SIDE EFFECT Before:
Mefenamic Acid Pharmacologic class:  Relief of moderate pain  upset stomach  Check and Verify Doctor’s order
Nonsteroidal anti- when therapy will not  nausea regarding the medication.
Brand Name: inflammatory drug exceed 1 week.  heartburn  Check the MAR and follow the 10
Ponstel  For relief of acute to  dizziness rights for administering medication.
Therapeutic class: moderately severe pain.  drowsiness
Usual Analgesic  Make a medication card with the
Contraindications:  diarrhea
Dosage/Frequency: complete doctor’s order, name of
 Patient with heart disease  headache
500 mg TID Drug Action: the patient, bed number and room
and high blood pressure.
Mefenamic acid binds or ward.
Usual Route ADVERSE EFFECT
the prostaglandin Drug to Drug Interaction:  Ask the clients full name to verify
Per Orem synthetase receptors  persistent nausea/vomiting,
Blood pressure drugs- angiotensin- its identity
COX-1 and COX-2,  severe stomach/abdominal pain,
converting enzyme (ACE) inhibitors  Educate and explain the medication
Drug Order: inhibiting the action of  weakness to the client, how it works, why it is
Diuretics (water pills)- Mefenamic
Mefenamic Acid 500 prostaglandin synthetase.  dark urine given to her and the possible side
acid can decrease the effectiveness
mg x1 tab PO TID as As these receptors have  yellowing eyes/skin. effect.
of medications used to get rid of
ordered. a role as a major  Patient shoould take mefenamic
extra fluid in your body.
mediator of Anticoagulant, blood thinner- acid with food to avoid upset
inflammation and/or a warfarin stomach. This can give together
role for prostanoid with food, or milk to minimize GI
signaling in activity- adverse effects.
Reference: Comerford, K. C., & Durkin, M. T. (2020). Nursing 2020 drug handbook (Vol. 1 & 2). Philadelphia: Wolters Kluwer
 dependent plasticity, the  Do not use drug for a period
symptoms of pain are exceeding 1 week.
temporarily reduced.
During
Peak of Action:  Remind client to don’t crush or
2-4 hours chew the oral capsule. Swallow it
whole.
Onset of Action:  Monitor for signs and symptoms of
Varies reaction while taking the drug.
After
Half Life:  Discontinue drug promptly if
2 hours diarrhea, dark stools, hematemesis,
ecchymoses, epistaxis, or rash
Reference: Comerford,
occur and do not use again.
K. C., & Durkin, M. T.
(2020). Nursing 2020  Notify physician if persistent GI
drug handbook (Vol. 1 & discomfort, sore throat, fever, or
2). Philadelphia: Wolters malaise occur.
Kluwer  Remind client to not engage in
potentially hazardous activities
until response to drug is known. It
may cause dizziness and
drowsiness.
 Document the important details
regarding the medication
administration. This includes the
date, time, reaction to drug and
effect.

FERROUS SULFATE

Reference: Comerford, K. C., & Durkin, M. T. (2020). Nursing 2020 drug handbook (Vol. 1 & 2). Philadelphia: Wolters Kluwer
 INDICATIONS,
Drug Name/Dosage/ CLASSIFICATION/ NURSING CONSIDERATIONS IN
CONTRAINDICATION AND SIDE EFFECTS AND ADVERSE
Route /Frequency/ MECHANISM OF SIGNIFICANT OTHER AND
DRUG TO DRUG EFFECTS
Drug Order ACTION PATIENT
INTERACTION
Generic Name: Drug Class Indications: SIDE EFFECT Before:
Ferrous Sulfate: Therapeutic Class:  Iron-deficiency anemia,  vomiting  Check and Verify Doctor’s order
Hematinic prophylaxis for iron  diarrhea regarding the medication.
Brand Name: deficiency in pregnancy and  temporarily discolored tooth  Check the MAR and follow the 10
Feosol Pharmacologic Class: nutritional supplementation enamel and eyes rights for administering medication.
Iron preparation Contraindications:
Usual  Make a medication card with the
 Sideroblastic anemia, ADVERSE EFFECT
Dosage/Frequency: Drug Action: complete doctor’s order, name of
thalassemia,  nausea
1 cap BID Replaces iron stores the patient, bed number and room
hemosiderosis/hemochromat  constipation
needed osis or ward.
 epigastric
Usual Route for red blood cell  Ask the clients full name to verify
Per Orem  pain
development as well as Drug to Drug Interaction: its identity
 black and red tarry stools
energy and O2 transport Increase: action of iron preparation  Educate and explain the medication
Drug Order: and use; fumarate — to the client, how it works, why it is
Ferrous sulfate x 1cap contains 33% elemental ascorbic acid, chloramphenicol given to her and the possible side
PO BID as ordered. iron; gluconate, 12%; Decrease: absorption of effect.
sulfate, 20%; iron, 30%; penicillamine,  Confirm that the patient is
ferrous sulfate levodopa, methyldopa, candidate for iron deficiency
exsiccated fluoroquinolones, anemia or have an insufficient iron
l-thyroxine, tetracycline before treatment.
Pharmacokinetics Decrease: absorption of iron
PO: Excreted in feces,  Between meals for best absorption;
preparations—antacids, H2- may give with juice; do not give
urine, skin, breast antagonists, proton
milk; enters with antacids or milk, delay at least
pump inhibitors, cholestyramine, vit 1 hr; if GI symptoms occur, give
bloodstream; bound to E
transferrin; crosses after meals even if absorption is
placenta decreased; eggs, milk products,
chocolate, caffeine interfere with
Peak of Action: absorption
7-10 days  Vitamin C may enhance
absorption, advise your patient to
Onset of Action: take this if not contraindicated.
4 days
During
Reference: Comerford, K. C., & Durkin, M. T. (2020). Nursing 2020 drug handbook (Vol. 1 & 2). Philadelphia: Wolters Kluwer
  Swallow tabs whole; do not break,
Duration: crush, or chew unless labeled as
2-4 months chewable.
 Warn patient that stool may be
Reference: Comerford, dark or green.
K. C., & Durkin, M. T.
(2020). Nursing 2020 After
drug handbook (Vol. 1 &  Report if severe GI upset, lethargy,
2). Philadelphia: Wolters rapid respirations, constipation. If
Kluwer constipation occurs, increase
water, bulk, activity.
 Remind client to avoid reclining
position for 15-30 minutes after
taking product to avoid esophageal
corrosion
 Remind to follow a diet high in
iron; to avoid taking iron, dairy
products, calcium supplements
because they compete for
absorption.
 Document the important details
regarding the medication
administration. This includes the
date, time, reaction to drug and
effect.

Reference: Comerford, K. C., & Durkin, M. T. (2020). Nursing 2020 drug handbook (Vol. 1 & 2). Philadelphia: Wolters Kluwer