Professional Documents
Culture Documents
E3A1 Modul Neurosains
E3A1 Modul Neurosains
Exercise 3: Neurophysiology of Nerve Impulses: Activity 1: The Resting Membrane Potential Lab Report
05/11/22 page 1
Experiment Results
Predict Question:
Predict Question: Predict what will happen to the resting membrane potential if the extracellular K+ concentration is
increased.
Your answer : b. The resting membrane potential will become less negative.
What does it mean that the voltage just inside the membrane is negative?
You correctly answered: b. There are more negative charges than positive charges just inside the membrane.
What effect does increasing extracellular K+ have on the net diffusion of K+ out of the cell?
You correctly answered: b. It decreases the net diffusion of K+ .
Which way would Na+ move across the membrane if there were open Na+ channels?
You correctly answered: a. Na+ would diffuse into the cell.
The membrane has open K+ channels, and changing extracellular K+ concentration results in a change in membrane
potential. Changing the extracellular Na+ concentration does not significantly change the membrane potential. What do
your results suggest about the number or state (open or closed) of Na+ channels in the resting membrane of a neuron?
Your answer : a. Na+ channels are mostly open.
Correct answer: b. Na+ channels are mostly closed.
Experiment Data:
05/11/22 page 2
05/11/22 page 3
05/11/22 page 4
05/11/22 page 5
05/11/22 page 6
Post-lab Quiz Results
You scored 0% by answering 0 out of 3 questions correctly.
1. A negative membrane potential was recorded when the tip of the microelectrode was
You did not answer this question.
Correct answer: d. both inside the cell body and inside the axon.
2. Which of the following caused a change in membrane potential from -70 to -40 in the cell body?
You did not answer this question.
Correct answer: c. between the inside of the axon and the outside of the axon with control K+ ECF
05/11/22 page 7
Review Sheet Results
1. Explain why increasing extracellular K+ reduces the net diffusion of K+ out of the neuron through the K+ leak
channels.
You did not answer this question.
2. Explain why increasing extracellular K+ causes the membrane potential to change to a less negative value. How well
did the results compare with your prediction?
You did not answer this question.
3. Explain why a change in extracellular Na+ did not significantly alter the membrane potential in the resting neuron?
You did not answer this question.
4. Discuss the relative permeability of the membrane to Na+ and K+ in a resting neuron.
You did not answer this question.
5. Discuss how a change in Na+ or K+ conductance would affect the resting membrane potential.
You did not answer this question.
05/11/22 page 8