Exclusion Criteria For PanTum

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ZYAGNUM The PanTum Detect Test uses the immune system diagnostically to detect evidence of possible tumor devel- ‘opment. The testis designed for allegedly healthy people without symptoms to use as part of PanTum's an- rnual cancer screening to detect a tumor disease early and before symptoms develop. Exclusion Criteria Customers of the PanTum Detect should therefore be healthy and symptom-free at the time of blood collec- tion. This ensures the highest quality of results, because in healthy, symptom-free people the immune system can be used in the best possible diagnostic way. In case of acute diseases or exhaustion of the immune system (e.g. cold, ever, inflammatory processes, neu- rodetmatitis or other rashes, cystitis, other severe inflammatory processes, etc.) we therefore strongly recom- mend to postpone the blood sampling date for PanTum Detect to 8 weeks after recovery. In the presence of symptoms that may be related to cancer (e.g, blood in the stool or urine, severe pain, severe weight loss, etc.) or in the case of acute suspicion of an existing tumor or cancer disease, a specialist should always be consulted. The PanTum Detect only serves as an indicative diagnostic and therefore cannot exclude a suspected cancer with certainty in the case of acute suspicion or the presence of symptoms. Only physicians ‘ith specialization in the respective medical field can provide professional medical treatment in such cases. Participation in PanTum Detect is not possible if the following dietary supplements or drugs are taken, or if any of the diseases or procedures listed here are present, Diseases: = Tumor and cancer diseases that have been treated in any way (surgery, radiotherapy, chemotherapy, hormone therapy, immunotherapy, etc. are basically cases of professional onco-logical follow-up and therefore excluded from PanTum Detect -> wait at least 5 years after successful cure. = Myeloproliferative neoplasia (MPN) and myelodysplastic syndrome (MDS) (leukemia!).. = Acute herpes zoster (shingles) -> wait another 8 weeks after complete recovery. = Injuries / wounds / bleeding (e.g, bone fractures, deep cuts, fresh tattoos, external or internal open ‘wounds, torn ligaments, blood in stool, blood in urine) > wait another 8 weeks after complete recovery. = Operations and interventions that have led to tissue injuries (also mirroring, dental treatment, et.) > wait another 8 weeks after complete recovery - Vaccinations of any kind > wait 8 weeks Contrast media (e.g. for MRI) > wait 8 weeks Drugs: (within the last 8 weeks) = Immunosuppressants ©.Cortisone > 5mg / day (high dose therapy); 1x cortisone > Smeg, then wait 4 weeks ‘After transplantation olxekizumab / Taltz = GM-CSF (immunostimulant) = MTX methotrexate}. ‘Nutritional supplements; (within the last 8 weeks) + Amygdalin ZYAGNUM AS +49 (0) 6151 365 510 +49 (0) 6181 565 5110 ReilstraBe 1 EMal: info®2yagnum.com DET! 5085 2651 0110 1571.69, 64319 Plungstoat www2yagnum.cam MELADEFI

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