Tripoli University Faculty of Medicine

Department of Pharmacology
MID Term exam for medical students

Student Name______________________
Student NO_________________________

Date 14.05.2017 Time 45 Min.

Answer all the following MCQs and make sure that you have 15 MCQs and transfer your answer to the
computer sheet.

1. Which of the following cephalosporins is more active against gram negative microorganism?
a. Cephalothin. c. Cefepime.
b. Cefaclor. d. Cephazolin.

2. Which of the following penicillins is used for infections induced by staphylococcus producing
β lactamase?
a. Ampicillin. c. Cloxacillin.
b. Amoxycillin. d. Penicillin G.

3. Please mark the incorrect statement regarding chloramphenicol:

a. A very popular antibiotic can be used in the treatment of common infections.
b. Not effective against chlamydial infections.
c. Commonly used antibiotic in the treatment of eye and skin infections.
d. Contraindicated in patient who is taking warfarin or phenytoin.

4. Kernicterus is atypical side effect of:

a. Penicillins. c. Cephalosporins.
b. Sulfonamides. d. Quinolones.

5. Which of the following is incorrect regarding Ciprofloxacin?

a. Has better gram -ve activity.
b. Effective against anaerobic bacteria.
c. Has higher serumtissue and intracellular concentrations compared to non-fluorinated
quinolones.
d. Has moderate to good activity against gram -ve bacteria.

6. Cilastatin is usually combined with:

a. Amoxycillin. c. Trimethoprim.
b. Imipenem. d. Sulfamethoxazole.

7. One of the following sulfonamides is used to treat ulcerative colitis:

a. Sulfadiazine. c. Sulfacetamide.
b. Sulfasalazine. d. Sulfamethoxazole.

By MOTAZ
8. Which of the following Quinolones considered active against anaerobic bacteria?
a. Trovafloxacin. c. Ciprofloxacin.
b. Nalidixic acid. d. Ofloxacin.

9. Which of the following drugs is an advanced generation cephalosporins:

a. Meropenem. c. Cefepime.
b. Ceftaroline. d. Ceftazidime.

10. Regarding tetracycline all the following are true EXCEPT:

a. Oxytetracycline is a short acting antibiotic and incompletely absorbed from stomach.
b. Minocycline is completely absorbed and excreted through the liver.
c. Demeclocycline is primarily excreted through the kidney.
d. Minocycline is useful in the treatment of acute meningococcal infections.

11. All the following are β- Lactam antibiotic EXCEPT:

a. Cephalexin. c. Imipenem.
b. Trimethoprim. d. Carbenicillin.

12. Regarding macrolides one statement is false:

a. Macrolides is a narrow spectrum antibiotic.
b. Erythromycin estolate is an acid resistant dosage form.
c. Is a common alternative for penicillin in case of β lactam resistance infection.
d. Bacteriostatic at low dose that act as bactericidal at certain doses for some species of
microbes.

13. Which of the following is anti-pseudomonal penicillin?

a. Azlocillin. c. Penicillin V.
b. Nafcillin. d. Methicillin.

14. All the following are adverse effects of aminoglycosides, EXCEPT:

a. Ototoxicity. c. Hepatotoxicity.
b. Nephrotoxicity. d. Neuromuscular blocking activity.

15. All the following are correct regarding aminoglycoside antibiotics, EXCEPT:
a. Bind with 30s subunit bacterial ribosome to inhibit protein synthesis.
b. Not given orally because of high first pass metabolism.
c. They are mainly effective against gram negative enteric bacteria.
d. Usually given with β- lactam antibiotics for synergism.

All Best Wishes

MOTAZ

By MOTAZ
 Key Answer

1 C
2 C
3 A
4 B
5 B,D
6 B
7 B
8 A
9 B
10 D
11 B
12 C
13 A
14 C
15 B

By MOTAZ