Food Toxicology

Course Description

Food toxicology is the study of the nature, properties, effects, and

detection of toxic substances in food or food animal feed and their disease
manifestation in humans. This course will provide a general review of
toxicology related to food and the human food chain.

Objectives:

Fundamental concepts will be covered including:

- Dose‐response relationships, absorption of toxicants,
- Distribution and storage of toxicants, biotransformation and
- Elimination of toxicants, target organ toxicity, teratogenesis,
- Mutagenesis, carcinogenesis, food allergy, and risk -assessment. The
course will examine chemicals of food
- Interest, such as food additives, natural products, mycotoxins, and
pesticides, and how they are tested and regulated.
-We will critically review case studies and special topics

learning Outcomes:

Upon successful completion of this course, students will

1. be able to demonstrate a fundamental knowledge of processes and

endpoints in the human body associated with exposure to toxic agents in
the human food chain;
2. be able to demonstrate a fundamental knowledge of risk assessment
and food safety as it is applied to toxic agents in the human food chain;
3. acquire mastery with the major issues, concepts, and subject areas in
food toxicology;
4. acquire mastery of sourcing and synthesizing information in aspects of
Food Chemistry, Toxicology and Microbiology as it applies to chemical
food safety and food toxicology;
5. be able to demonstrate sufficient knowledge about the occurrence and
significance of major food-borne toxicants and be able to apply that
knowledge for advanced analysis in the context of the food system,
regulatory science, and public communication.

Course contents:

1. Introduction to food toxicology

2. Toxicity testing and risk assessment
3. Environmental contaminants and drug residues in food
4. Pesticide residues in food
5. Absorption, distribution, and Elimination of Toxicants
6. Teratogenesis, Mutagenesis, and Carcinogenesis
7. Mid-term exam
8. Food allergies and sensitivities
9. Food Intolerance and Metabolic Disorders
10.Food Additive Safety Assessment
11.Analysis of toxicants in Food Products