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Robotic-Arm Assisted

Unicompartmental Knee Arthroplasty 111


(MAKO)

Frederick Buechel Jr, Frederick Buechel Sr, and


Michael Conditt

Contents Coronal View . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1286


Sagittal View . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1287
Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1282
Femoral Planning Screens . . . . . . . . . . . . . . . . . . . . . . . . 1287
Robotic-Arm Assisted Partial Knee Arthroplasty Sagittal View . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1287
Solution . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1283 Transverse View . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1288
Features of the MAKO Robotic-Arm Assisted Coronal View . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1288
Partial Knee Replacement System . . . . . . . . . . . . . . . 1283 Patellofemoral Planning Screens . . . . . . . . . . . . . . . . . 1288
Indications for PKA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1283 Preplanning for the Patellofemoral Replacement:
X-Ray and Imaging Indications . . . . . . . . . . . . . . . . . . 1284 Three Basic Steps . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1288
Steps 1 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1288
Medial Compartment X-ray Indications . . . . . . . . 1284 Steps 2 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1288
Steps 3 . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1290
Lateral Compartment X-ray Indications . . . . . . . . 1284
Surgical Process . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1290
Patellofemoral Compartment X-ray
Indications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1284 Robot Setup . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1290
CT Imaging Preoperative Planning . . . . . . . . . . . . . . 1284 Patient Setup . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1290
Preoperative Planning . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1284 Exposures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1291
Preoperative Planning Overview . . . . . . . . . . . . . . . . . 1285 Checkpoints . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1292
Preplanning Screens: Optimal Starting Position Tracking Arrays . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1292
Medial and Lateral PKA . . . . . . . . . . . . . . . . . . . . . . . . . 1286
Registration . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1293
Tibial Planning Screens . . . . . . . . . . . . . . . . . . . . . . . . . . . 1286
Transverse View . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1286 Osteophyte Removal . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1294
Pose Captures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1294
Cartilage Mapping . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1294
F. Buechel Jr (*) Medial and Lateral PKA . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1294
Robotic Joint Center at The Stone Clinic, San Francisco, Patellofemoral PKA . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1295
California, USA Examples of Reasonable PKA Alignment Goals
e-mail: ffbjr@me.com in Specific Scenarios . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1295
F. Buechel Sr Intraoperative Planning . . . . . . . . . . . . . . . . . . . . . . . . . . 1297
South Mountain Orthopaedics, South Orange, NJ, USA
e-mail: fbuechel@me.com Balancing Graph . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1297
M. Conditt Tracking . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1298
Holy Cross Hospital, Fort Lauderdale, FL, USA
e-mail: Michael.Conditt@stryker.com

# Springer International Publishing Switzerland 2016 1281


G.R. Scuderi, A.J. Tria (eds.), Minimally Invasive Surgery in Orthopedics,
DOI 10.1007/978-3-319-34109-5_122
1282 F. Buechel Jr et al.

Bone Preparation (Robotic-Arm Assisted Introduction


PKA) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1298
Implantation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1300 Robotic-arm assisted partial knee arthroplasty
Kinematic Analysis . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1301 (RA-PKA) is the designation for the
unicompartmental knee arthroplasty (UKA) pro-
Clinical Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1302
Clinical Outcomes . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1302 cedures performed using the MAKO robotic
orthopedic system currently available for use in
Accuracy of Component Positioning . . . . . . . . . . . . . 1302
the USA and internationally. Arthroplasty proce-
Accuracy of Joint Balancing . . . . . . . . . . . . . . . . . . . . . 1302 dures performed using this system have been
Survivorship . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1303 commonly referred to as “Makoplasty ®” proce-
Discussion . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1303
dures. The first procedures for the knee were
performed on the medial compartment in June of
References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1304
2006 [1]. Over the last 10 years, the procedures
being offered using this platform have expanded
to include the lateral compartment [2–5],
patellofemoral compartment, and total hip
replacement, and now total knee replacement.
Successful minimally invasive surgery still
requires a surgeon to perform appropriate place-
ment of limited skin incisions and deep expo-
sures, while attending to the soft tissues. While
this robotic precision tool can assist surgeons in
bone preparation through small windows into
the body, it is the surgeon’s responsibility to
plan the procedure and protect the patient’s tis-
sues from injury with appropriate handling and
retraction. The MAKO robot allows surgeons
using minimally invasive approaches to achieve
precision bone preparation and implant installa-
tions customized for each patient [1, 3, 6–8]. Pre-
operative detailed evaluation of the effected
knee imaging allows surgeons to precisely plan
their implant starting position and prepare for
the anatomical variations each patient presents.
Intraoperative computer adjustment based on
live kinematic data collected during surgery
allows for subtle implant position corrections
prior to bone resection to achieve a fully bal-
anced, properly tracking, and optimally placed
implant. Published results have confirmed posi-
tional accuracy, greater patient satisfaction,
improved short-term survivorship, and func-
tional improvements over previous nonrobotic
techniques. [3, 6–17]
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1283

Robotic-Arm Assisted Partial Knee to: full range of motion gap analysis, tracking
Arthroplasty Solution data, and cartilage surface mapping
• A true robot, with a robotic-arm that has a
Robotic-Arm Assisted PKA provides solutions 6 mm bone preparation burr at its end that
to the problems associated with manual PKA. A communicates with the software plan and
computerized 3D planning software package cre- assists the surgeon by using virtual boundaries
ates a preoperative starting implant position and to accurately prepare the bone
sizing plan, to later be adjusted intraoperatively. • Robot specific implants anatomically designed
Optimizing the intraoperative plan is logical and on the femoral articular surface, while the bone
allows the surgeon to use kinematic data in the surface side takes advantage of the 6 mm round
OR to optimize final implant position before burr, requiring less bone removal
bone preparation. Full range of motion femoral • A verification process before, during, and after
on tibial tracking and gap distance equalization is implant installation that allows confirmation of
achieved while live surface mapping of the fem- cutting depth, trial component position, and
oral cartilage allows the transition of the implants final component position in the cement mantel
to the cartilage to be optimal. The final • A kinematic analysis option in the software to
intraoperative implant plan provides highly allow comparison of the femoral-tibial gap
accurate sizing, tracking, and balance for the planning through the range of motion before
knee implants. The intraoperative plan commu- bone cutting, again with the trial implant
nicates with the robotic-arm, which provides tac- installed with the gaps achieved, and the final
tile feedback to the surgeon during bone gaps achieved with the implants cemented that
preparation. The surgeon then guides the match the plan, before closure
robotic-arm over the area of bone to be removed
while the system provides tactile, virtual bound-
aries only allowing bone removal at the planned Indications for PKA
location and virtually stops the tool from going
further. In essence virtual cutting blocks are cre- Critical to the success of PKA when deciding on
ated for each patient specific to his or her which patients should or could receive a RA-PKA
intraoperative customized plan. is understanding the indications for the patient and
the goals for the surgeon. Considerations in the
decision process include the patient’s medical and
Features of the MAKO Robotic-Arm surgical history, specific locations of pain in the
Assisted Partial Knee Replacement knee, physical exam findings, radiographic find-
System ings, psychological issues, and social situations
[18–21].
The MAKO robotic-arm assisted PKA system The patient history for those properly selected to
package: undergo RA-PKA should include knee pain from
osteoarthritis, osteonecrosis, noninflammatory
• A sophisticated preoperative and intraoperative arthritis, or posttraumatic arthritis no longer
planning CT-guided software package responsive to nonreplacement interventions. Tradi-
• Computer navigation with infrared sensors and tional indications provide a solid framework for
arrays surgeons beginning with robotic-arm assisted par-
• An intraoperative kinematic data acquisition tial knee replacement however, as they become
process that allows for real-time intraoperative more skilled with the computer pre-planning and
adjustment of the preoperative plan according intraoperative planning adjustments the system
1284 F. Buechel Jr et al.

allows, more challenging cases can be handled preserved. There can be some small osteophytes
satisfying more patients. on the medial femur or tibia but there should be no
Patients that require isolated medial, lateral, or pain there. There should be no significant lateral
patellofemoral compartment procedures generally subluxation of the patella on lateral compartment
will point directly to the compartment. Patients for patients.
medial or lateral only PKA should not complain of
anterior knee pain at the location of the patella or
patella tendon with stair climbing or rising from Patellofemoral Compartment X-ray
chairs. Patients considering patellofemoral Indications
replacement should not have a history of signifi-
cant malalignment or patella instability. The patellofemoral space can have some mild,
moderate, or severe wear. There should be good
tracking of the patella in the trochlear groove, and
X-Ray and Imaging Indications there should not be severe lateral subluxation of
the patella. There may be large superior, inferior,
A standard weight bearing AP, weight bearing 45 lateral, or medial patella osteophytes. The medial
PA flexion view, lateral, and sunrise patella view and lateral compartments should be well pre-
are all needed to properly evaluate the knee. If the served on x-ray. Poor tracking is not alleviated
weight bearing 45 PA flexion view is not with resurfacing alone [18, 19].
obtained or poorly angled, a significant percent-
age of patients with moderate to severe posterior
medial or lateral femoral cartilage loss will be CT Imaging Preoperative Planning
missed and the diagnosis will not be made cor-
rectly. A sunrise or Merchant view is important to Once the patient is indicated to proceed with a
assess the tracking and joint space of the robotic-arm assisted partial knee arthroplasty
patellofemoral compartment. from the office exam and x-rays, a low dose
CT scan of the extremity is performed for the
planning and execution of the procedure.
Medial Compartment X-ray Indications Detailed 1 mm slices of the knee are taken
with 5 mm slices of the hip and ankle. The
Mild, moderate, or severe bone on bone medial robotic company in-services the CT facility,
compartment joint space loss are indications for provides the protocols and a motion detection
medial RA-PKA. The lateral side should be well rod for use during the scans required for the
preserved. There can be some small osteophytes procedure.
on the lateral femur or tibia but there should be no The scan is then manually “segmented” to
pain there. The patellofemoral space can have create the 3D models seen by the surgeon for
some mild or moderate wear but not bone on preoperative implant planning. This is done
bone. There can be large superior, medial, or “behind the scene” and is not part of the surgeons
inferior patella osteophytes as long as there is no planning but allows the images for the surgeon’s
significant pain on exam. planning screens to be created. This segmentation
process takes approximately 30 minutes for PKA.

Lateral Compartment X-ray


Indications Preoperative Planning

Mild, moderate, or severe bone on bone lateral This is the initial preoperative placement of the
compartment joint space loss are indications for virtual implants onto the tibial, femoral, or troch-
lateral RA-PKA. The medial side should be well lear bone surfaces depending on the procedure.
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1285

Fig. 1 Basic planning for medial PKA

The company representative performs the initial understand proper planning, data acquisition,
planning. The surgeon locally evaluates this plan and final goals.
and fine adjustments to the preplan can be Intraoperative plan adjustments are finalized to
performed in the clinic or in the operating room guide bone preparation. After tracking arrays are
prior to the start of the procedure. Preoperative attached, the bones are registered to the CT bone
planning allows selection of the sizes and position models, the osteophytes have been removed, and
of the implants that best fit the patient (and stores kinematic data is collected with the knee passively
alternative size plans the surgeon creates). Pre- corrected to the stable endpoint of the collateral
plans allow planning of the implant depth, sagit- ligaments through full motion.
tal, coronal and transverse rotation, posterior There are both tibial planning screens and fem-
slope, coronal plane alignment, and initial track- oral planning screens used by the surgeon.
ing position from the patient alignment lying The surgeon’s preoperative size choice will
supine during the CT scan (Fig. 1). almost always be obvious from the rules I will
provide. Occasionally patients may be between
sizes, so surgeons can plan two implant sizes
Preoperative Planning Overview and choose the right one intraoperatively using
probes to precisely identify the best size and fit
Planning both preoperatively and dynamically in these few cases. The system will store all sizes
intraoperatively is the key to the robotic-arm preplanned for the surgeon to test virtually during
assisted partial knee surgery process. The cutting surgery.
will always be accurate to the planning with the Later during the surgery, a calibrated handheld
robotic-arm, so it is up to the surgeon to probe with a pointer tip can be used after registration
1286 F. Buechel Jr et al.

Fig. 2 Arrows point to the specific key regions to evaluate during preplanning

to identify any position on the patient and display it


on the virtual preplan. This will confirm and display Tibial Planning Screens
the bone edge locations, the position of the virtual
implant on the real patient, and identify the location Transverse View
of the ACL fibers in relation to the virtually planned
tibia. This probe technique is used to help make a Medial
proper size or position choices for the implant on • Maximize cortical coverage without overhang
those in-between sizes. on any slice.
• Keep the medial edge of the implant right on
the tibial cortex but no over hanging on any
Preplanning Screens: Optimal Starting slice.
Position Medial and Lateral PKA • Fit the implant into the best position to cover
the surface (Fig. 2).
The tibial and femoral preplan screens each have
four windows on the left side. The three CT bone Lateral
windows allow coronal, sagittal, and transverse • Internally rotate the implant 8–15 (I choose to
views that can be reviewed as individual 1 mm start at 10 and adjust as needed). This will be
slices and allow surgeon-controlled adjustment of the usual final rotation for lateral tibias to
the virtual implant. The top right window is a accommodate for the screw home mechanism.
virtual 3D reconstruction of the patient’s tibia, • Medially shift the implant 2 mm from the cor-
femur, or both created from the segmentation pro- tical edge to start.
cess. It can be used as a guide to see the location of • Ensure there is good anterior and posterior
the CT slice being adjusted in one of the three cortical coverage, as this position is usually
bone windows, and it can be rotated to look at the needed to get central femoral contact on the
knee from any angle and is used to evaluate track- bearing and provides cortical rim load bearing
ing intraoperatively. to avoid subsidence
The arrows at the top left of each window allow
for 0.2 mm movements of the implant, and rota- Coronal View
tion in 1 increments from any user chosen point.
On the right side of the screen are several menus, Medial
options, and functions used by the surgeon and • Keep the medial edge of the implant right on the
representative during implant planning. tibial cortex but not overhanging on any slice.
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1287

• Avoid ACL intrusion and do not undermine the • Keep the implant as high as possible while still
medial tibial eminence with the lateral side of making contact with the posterior tibial bone
the implant by staying medial to “half way up surface, do not overhang anteriorly.
the tibial eminence’s sloped lateral edge.” You • Contact on the posterior and anterior cortex is
can sometimes go slightly more lateral but mandatory, as the lateral edge is often not mak-
check intraoperatively with the probe to ensure ing contact over the cortex for proper tracking
you are not too far lateral and invading the since we medialize it 2–4 mm.
ACL during surgery. (If so, go to the next
smaller implant.)
• Set coronal alignment 1 varus. Femoral Planning Screens
Lateral Sagittal View
• Adjust lateral edge of the implant 2–4 mm
medial to cortical edge. • Plan with the CT slice going through the mid-
• Set coronal alignment 1 valgus. dle anterior tip of implant.
• Reproduce anatomic femoral shape with the
Sagittal View implant position.
• Size and shape match femoral component to
Medial condyle.
• Match patients tibial slope. • Place implant’s posterior condyle at or just
• Starting implant composite height should be ½ within the subchondral bone outline.
above ½ below the cortical bone surface seen • Keep the anterior tip of the implant ½ in ½ out
as the magenta bone outline. of the bone outline.
• AP cortical coverage does not have to be com- • Place anterior tip at or just posterior to sulcus
plete on medial side if the implant is invading terminalis to start.
too far into the tibial eminence and ACL on the • If between sizes, choose the smaller size to
coronal view. The medial cortex will support start, especially on the lateral components.
the implant. • To make sure the femoral component is large
enough, the anterior tip should to be at or in
Lateral front of the anterior tibial bearing edge with the
• Match patients tibial slope. tibial implant view on (Fig. 3).

Fig. 3 Arrows point to the specific key regions to evaluate during preplanning
1288 F. Buechel Jr et al.

Transverse View remaining cartilage. With the bicompartmental


planning, the software allows independent posi-
• Positions the posterior femoral condyle of the tioning of both components and avoidance of
implant for optimal tracking in deep flexion. contact between the two metal implants.
• Stay inside the condyle’s cortical edges on all Preplanning provides a starting position for all
views. of the main transitions and 3D aspects of the
• Try to approximate the posterior condyle sur- trochlea. The intra-operative planning steps
face angle, but medials are often in a more allow for final accurate mapping of all the
internally rotated and lateralized position. implant to cartilage and bone transitions, and
the cartilaginous trochlear groove location, so
Medial adjustment can be made to optimize trochlear
• Keep implant lateralized close to the notch position prior to bone preparation (Fig. 4).
cortex but not in notch on any slice. The trochlear groove of the virtual implant has
a black line showing its path on the planning
Lateral screen. The implant’s virtual tracking line will
• Laterals center the implant in the posterior later be matched to the patient’s trochlear groove
condyle. reproducing the correct angle for each patient.
• The condyle is always small and just fits the During the intraoperative planning the native
implant centered. trochlear groove is mapped with a probe and
visualized on the software virtually, allowing for
translation of the virtual implant plan to the true
Coronal View trochlear groove position.

• Positions the anterior tip and distal part of the


femoral component. Preplanning for the Patellofemoral
• Ensures the distal implant is out of the notch Replacement: Three Basic Steps
and contacting on bone.
Steps 1
Medial
• Position anterior tip at the junction of the mid- Using the “PF Primary Screen” the size is chosen
dle and medial third of the condyle. on the transverse view leaving about a millimeter
of remaining bone on either side, rotation is set,
Lateral and position is matched to the native shape. The
• Place anterior tip on the lateral cortical edge, implant’s proximal lateral flange is set just into the
keeping the posterior implant centered in the anterior cortex on the sagittal view, and on the
condyle on the transverse view. coronal view setting the pink “wings” equal dis-
• Choose the smaller size if you are between tance from the distal femur as a transition guide
sizes. from implant to cartilage or onto the medial fem-
oral component in the bicompartmental cases
(Fig. 5).
Patellofemoral Planning Screens

Preplanning the trochlear component for isolated Steps 2


patellofemoral or bicompartmental procedures
are both performed the same way. This sets the The “Verify 2 Screen” adjusts component in the
parameters for an inlay trochlear component AP plane so that mid-proximal tip is split midway
avoiding a proximally proud component or a between the cortex. The distal tip is positioned
proud edge where the implant transitions onto anterior to Blumensaat’s line, and the distal tip is
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1289

Fig. 4 Starting view for preplanning a patellofemoral replacement

Fig. 5 Step 1 for preoperative planning trochlear component position


1290 F. Buechel Jr et al.

Fig. 6 Step 2 for preoperative planning trochlear component position

split midway between bone. Then adjust the flex-


ion extension of component and AP position to be Robot Setup
approximately 2 mm proud of trochlear groove
bone (Fig. 6). The robot is brought into the OR prior to the
patient and surgeon, and the representative and
the scrub nurse perform the startup process. This
Steps 3 turn on and “honing process” validates the func-
tioning of the robotic-arm and registration tools.
The “Verify 1 Screen” is used to adjust AP com- The robot is draped sterilely and the cutting burr
ponent position so that the medial proximal flange and irrigation system is connected. The patient’s
is just on the surface of the anterior femoral cortex CT data file is loaded into the computer station
(Fig. 7). and the preplan is brought up on the screen for
the surgeon to review and adjust if necessary
Surgical Process (Fig. 8).

Using the Mako robotic-arm assisted PKA system


with a minimally invasive approach, patients can Patient Setup
be consistently discharged to home on the same
day, with an overnight stay option for some due to Standard setup with sterile drapes applied to the
regional differences. A well-rehearsed team leg with preferably an impermeable stockinet
approach to managing this procedure will make from the toes up over the top of the tourniquet
the experience efficient, safe, and comfortable for is seen in the photo. A wrap secures the stockinet
the patient, the surgeon, the anesthesia team, and from the toes up to the mid-tibia. The patient’s
the operating room staff. leg is secured in a padded adjustable foot holding
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1291

Fig. 7 Step 3 for preoperative planning trochlear component position

Fig. 8 Honing Robot and Draping Process

device that allows assistant free positioning at


any angle or rotation during the procedure and Exposures
ample stability for robotic bone preparation
(Fig. 9). The incisions and exposures used for single com-
partment surgery are different from total knee inci-
sions and require proper soft tissue handling to
1292 F. Buechel Jr et al.

Fig. 9 Standard Patient Set-up in sterile leg holder for Robotic Partial Knee Replacement

Fig. 10 Exposures for


medial, lateral,
patellofemoral, and
bi-compartmental robotic
PKA

avoid traumatizing the skin, which can cause femoral condyle just superior and anterior to the
delayed tissue healing problems, skin edge necro- medial epicondyle. These are removed at the end
sis, and infection. It is best to perform the of the case and are used for verification of the
arthrotomy first, and then attach the bone tracking tracking array accuracy at the time of robotic bone
arrays to avoid shifting the arrays or having them preparation and to ensure the arrays have not been
interfere with the exposure process (Fig. 10). moved prior to bone preparation (Fig. 11).

Checkpoints
Tracking Arrays
With the arthrotomy completed, a small checkpoint
is pushed into the tibial anterior cortex 2 cm below Tracking arrays are placed in the femur and tibia.
the plateau at the base of the arthrotomy, and a These navigation tracking arrays are each
second is placed in the medial side of the medial clamped to two bone pins in the tibia and femur
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1293

Fig. 11 Checkpoints are


placed in each bone
temporarily to verify array
position accuracy before
bone preparation

Fig. 12 Tracking arrays


are attached to the bones to
allow for communication
between the planning
software, the patient, and
the robotic cutting tool

with 4.0 mm or 3.2 mm threaded pins. The fem-


oral pin placement 4 fingerbreadths above the Registration
patella in the direct anterior position works well,
just touching or penetrating the posterior cortex. Once the arrays and checkpoint are installed, reg-
The tibial pin placement 4 fingerbreadths below istration of the bones to the computer CT scan can
the tibial tubercle works well in the center of the be performed. This creates the real-time live bone
subcutaneous border. Deeply engaging the ante- models seen on the display for our intraoperative
rior cortex is all that is needed without penetrating planning process and guides our robotic bone
the posterior cortex (Fig. 12). preparation (Fig. 13).
1294 F. Buechel Jr et al.

Fig. 13 Registration is the


process by which the patient
and the virtual CT plan are
linked during the procedure

Registration starts with rotating the hip to The surgeon passively corrects the varus knee to
establish hip center. The ankle center is registered the MCL’s stable endpoint and puts the knee
with a probe placed at the subcutaneous center through motion from extension through flexion
position of both malleoli. The two checkpoints stopping momentarily along the way as the data
are registered by placing the probe into the check- is collected.
point divots. Thirty-two points on the femur are The software collects the live implant position
registered and 32 points on the tibia are registered. data virtually from the planned femoral and tibial
This provides three surface planes to accurately implants. A gap distance calculation is registered
match the CT data, within a millimeter, to the and a contact point is created at each pose
patient. Once registration is completed, the captured.
femur and tibial are communicating with the com- On the computer display the center of the tibial
puter software models. Real-time contact posi- bearing is represented at each pose captured as a
tions of the implants and the gap distance red dot on the virtual femoral component anima-
between the implants can then be collected for tion. The femoral component can then be trans-
intraoperative planning adjustments. lated and rotated to line up on these tibial center-
tracking points. The tibia can also be adjusted to
optimize tracking.
Osteophyte Removal The gap distance data between the planned
femoral component and top of the planned tibial
Before collecting kinematic data, the large bearing is displayed in millimeters on a bar
osteophytes that are tenting the medial or lateral side graph showing the gap at each position captured
of the knee soft tissue envelope need to be excised to from extension through full flexion (Fig. 14).
gain proper tensioning during data collection.
Cartilage Mapping

Pose Captures Medial and Lateral PKA

Pose captures or “position captures” are data Cartilage mapping is the final data collection
points collected and captured in the software step. Since the CT data on the computer screen
when the surgeon passively corrects the knee’s shows the bone and not the cartilage level, virtual
coronal plane deformity and ranges the knee. cartilage mapping with a blunt tip calibrated
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1295

Fig. 14 Knee deformity is passively corrected to collateral ligament stable endpoint while knee is put through ROM as
system collects data to optimize implant position

hand probe allows the surgeon to trace the carti- placement of the trochlear component. This feature
lage at the transition zones on the patient, and allows the surgeon to virtually map and display
this actual cartilage surface level data is overlaid Whiteside’s line of the native trochlea on the virtual
on the display. The surgeon can see the plan of plan. It also allows one to virtually map and display
the femoral component and the true cartilage all the actual cartilage to virtual implant transition
surface level to allow any adjustments to the zones. Once virtually mapped, the implant is trans-
anterior tip position of the femoral component lated and rotated to match Whiteside’s line and to
needed to ensure a proper transition occurs, and transition from the native cartilage smoothly onto
the implant is not proud of the cartilage surface, the implant distally, medial and laterally, and prox-
which could contact the patella during flexion imally onto the shaft (Fig. 16).
(Fig. 15).

Examples of Reasonable PKA


Patellofemoral PKA Alignment Goals in Specific Scenarios

During patellofemoral replacement, cartilage map- Varus Goal, Mild Deformity


ping is extensively used. Since there is no gap • Passively correct to stable MCL endpoint.
analysis in the patellofemoral procedure, this is • If 6 varus to start and corrects to 3 , good.
the primary adjustment tool used for final • If 4 varus to start and corrects to 1 , good.
1296 F. Buechel Jr et al.

Fig. 15 This allows the


cartilage level to be
virtually superimposed on
the CT scan plan allowing
adjustment of the femoral
component avoiding a
proud implant

Fig. 16 This allows the


true cartilage and bone level
to be virtually
superimposed on the CT
scan computerized plan
allowing optimization of the
trochlear component

Varus Goal, Fixed Deformity • Perform small medial sleeve elevation with
• Best to start with a 10 or less fixed varus. moderate fixed varus.
• Trim all medial osteophytes before pose • 30–50 % improvement common in some
captures. but not all.
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1297

• Severe fixed varus knees that start over side with releases, and the polyethylene
10–15 of varus often remain in significant bearing options are limited to 5 mm
varus. thickness.

Extension Goal, Mild Deformity Patellofemoral Goals


• Document starting extension, try to • The goal for the trochlear component is to
improve it, or reproduce good extension. reestablish the native trochlear groove by
• If start is 1–2 flexion contracture on com- mapping the native trochlea and placing
puter, try to achieve full extension to 0 . the implant trochlear groove in the same
location.
If the knee starts in 4 hyperextension, the goal is • Make sure the implant transitions smoothly
around 2–5 of hyperextension close to the to cartilage surfaces from the medial and
patient’s start but not more. lateral femoral condyles and the anterior
shaft, by cartilage mapping the transitions.
Extension Goal, with Flexion Contracture • Remove peripheral patellar osteophytes,
• Best to start with a 10 or less fixed properly resect the patella articular surface
contracture. and choose the best size implant to cover the
• Larger starting flexion contractures will resected surface.
retain more noticeable residual • Avoid leaving the patella un-resurfaced in
contractures. this design as it can potentially leave
• 30–50 % improvement is common on fixed patients with painful flexion from 20 to 60 .
contractures with proper planning and
osteophyte removal.
• Graph planning should increase the gap dis-
tance in early extension to allow for reduc-
tion in contracture and the ability to stretch Intraoperative Planning
more over time.
• Removing larger posterior osteophytes off An optimized plan has a balanced graph, central-
femur and tibia can improve extension. ized implant tracking, and an optimized implant to
• Removing anterior tibial osteophytes that cartilage transition at the tip of the anterior femo-
impinge in the notch improve extension. ral component that is achieved through cartilage
• Many of these contractures will stretch mapping (Fig. 17).
and reduce over 6–12 months with
removal of the osteophytes and balancing
the knee. Balancing Graph

Lateral Goal, Mild Valgus The balancing graph allows surgeons to opti-
• Flexible deformities that do not overcorrect mize the gap distance between the virtually
to varus and start at less than 10 of fixed planned femoral component and tibial bearing
valgus are acceptable. at each part of the range of motion that data is
• Avoid the valgus knee alignment that cor- captured. The graph represents a gap as a blue
rects into varus and will overload the medial vertical bar going up on a millimeter scale seen
natural side. on the left “y axis.” Bars go from left to right
• Severe valgus >10 that is fixed is not a (extension to flexion) and represent the gap
case for PKA at this time. exactly where the surgeon stopped to take a
• Lateral releases are not recommended as the pose capture through the range of motion, on
gaps can become significant on the lateral the “x axis.” The vertical bars define the
1298 F. Buechel Jr et al.

Fig. 17 Each patients


implant positioning plan is
optimized intra-operatively
from real-time interactive
data during surgery

virtual space remaining between the virtual


implants with the MCL tensioned at each Tracking
position.
As we optimize the graph, our goal is to allow a A key feature of this system is its ability to allow
slight gap to be possible between the implants surgeons to optimize the tracking of the femoral
when the knee is passively corrected allowing component on the center of the tibial component.
for some elasticity in the MCL. In the past, this This is based on the kinematic tracking contact
was performed by placing a spacer or tongue data collected during the pose capture step taken
depressor into the gap after the bone cuts were during range of motion. Performed by flexing the
made and the implants were installed. With knee and holding the foot pointing straight for-
MAKO robotics, we move the tibia and the ward with consistent corrective tension applied to
femur independently to predictably achieve a the knee, the surgeon passively corrects the varus
well-balanced knee (a symmetric gap throughout on medial OA knees or passively corrects the
the arc of motion) on a virtual planning graph, valgus on lateral OA knees (Fig. 19).
optimizing the position before we cut the bone
with the robotic cutting tool.
The gap between the implants at each part of Bone Preparation (Robotic-Arm
the range of motion can be optimized for each Assisted PKA)
patient’s dynamic movements and ligament ten-
sions by moving the virtual implants up or down, Once the final intraoperative plan has been opti-
right or left, or rotating them. The adjustments are mized, the information is locked into the computer
seen real-time on the graph as the implants are plan that guides the robotic-arm during bone prep-
independently moved. The implants can be aration. The 6 mm burr connected to the end of the
rotated in 1 increments and can be moved up robotic-arm assists the surgeon in removing the
and down, right or left in 0.2 mm increments planned volume of bone resection. The robotic-
(Fig. 18). arm provides the surgeon audible and tactile
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1299

Fig. 18 Intra-operative
implant adjustment allows
for fine-tuning of each
patients ligament balance
throughout the range of
motion from kinematic data
collected

Fig. 19 Optimized
tracking prevents edge
loading that can lead to
early wear or loosening

feedback limiting the area of resection to the plan. bone level is achieved. When the green has
The system creates virtual boundaries like an all been removed, the preparation is complete.
“invisible wall” that limits the movement of the The system provides an audible sound when the
cutting burr only to the volume planned. robotic burr gets close to the boundary of
The surgeon then pushes the burr tip across the the planned resection. If pressure is continued,
bone, and on the monitor the green bone area to be the color will turn to red. If an attempt is made
removed begins to disappear as the final white to go beyond a millimeter past the plan, the cutting
1300 F. Buechel Jr et al.

Fig. 20 Robotic-Arm
assisted bone preparation
provides accuracy and
safety

tool (burr) will be shut down and the surgeon is


physically stopped from going further.
Bone preparation is the easy part of the proce-
dure, as the robot will not let you remove the bone
anywhere except where you plan. Planning is
therefore the critical part of the procedure. The
surgeon’s responsibility during the robotic part of
the procedure requires an awareness of the soft
tissues to ensure the tool is being introduced into
the soft tissue window safely, avoiding injury to
skin, tendon, or ligaments, by using proper retrac-
tors where appropriate (Fig. 20).

Implantation

See Fig. 21.


With the trials in place, the surgeon will assess
the knee for stability and range of motion. The
final metal components are cemented in standard Fig. 21 Trail Implants installed and all bone edges and
fashion inserting the tibial tray first, then the fem- soft tissues trimmed flush to implant to avoid impingement
oral component. or irritation
The final polyethylene insert is chosen after
the metal implants have stabilized in the cement while simultaneously evaluating the motion
and any excess cement is removed posteriorly. achieved on the computer, prior to choosing the
Stability is then checked with the trial inserts final polyethylene insert thickness. (Fig. 22).
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1301

Fig. 22 Lateral PKA tibial bearing seated in tray on left ready to be impacted into the locking mechanism which is seen
on the right fully seated

Fig. 23 Kinematic analysis compares the preplanned pas- trial installation is seen here on the graph as the horizontal
sively corrected virtual implant gaps to the final passively yellow line between the planned and actual gap, at each
corrected gaps with the trial implants installed and the final data point collected
implants installed. The difference in the planned verses the

The final intraoperatively planned gaps are


Kinematic Analysis overlaid with the final gaps taken with the trial
implants installed and can also be shown with
See Fig. 23 the final cemented implants. The different color-
The software provides an option for surgeons coded bars on the graph show the difference
who wish to validate that what they planned on between the planned gap, trial gaps, and the
the balancing graph has actually occurred once final installed gaps. The knee is closed in the
all the trials and final components are installed standard fashion.
[15]. This is called the kinematic analysis.
1302 F. Buechel Jr et al.

Clinical Summary more varus relative to the mechanical axis of the


tibia. This compared with an average error of 0.2
Clinical Outcomes  1.8 using robotically guided technology. Fur-
thermore, the varus/valgus root mean square error
Several studies have shown significant improve- was 3.4 manually compared with 1.8 robotically.
ments using robotic assistance for UKA postop- Pearle et al. [9] compared robot-assisted and tradi-
eratively (compared to preoperative levels) in tionally instrumented UKA in six bilateral pairs of
ROM, Knee Society Scores, WOMAC scores, cadaver specimens. In all knees, a CT-based pre-
and SF-12 scores [8, 16, 22, 23]. operative plan was performed to determine the
ideal position and orientation for the implant com-
ponents. Postoperative CT scans were obtained
Accuracy of Component Positioning from all knees, and the 3D placement errors were
quantified using 3D-to-3D registration of implant
In a study by Roche et al. [23], postoperative and bone models to the reconstructed CT volumes.
radiographs of 43 robotic UKA patients were Femoral component RMS placement errors (posi-
examined for outliers. Of the 344 individual radio- tion and orientation along any single axis) were on
graphic measurements, only four (1 %) were iden- average of 3.0 times more accurate ( p<0.05) and
tified as outliers. Coon et al. [8] examined a cohort 3.1 times less variable ( p<0.05) with robotic guid-
of 33 robotic and 44 standard UKA patients. The ance. Similarly, tibial component RMS placement
coronal and sagittal alignment of the tibial compo- errors were on average of 3.4 times more accurate
nents were measured on postoperative AP and ( p<0.05) and 2.6 times less variable ( p<0.05)
lateral radiographs and compared to the preopera- with robotic guidance. Roche et al. [11] utilized
tive plan. The root mean square (RMS) error of the the same postoperative CT technique to prospec-
tibial slope was 3.5 manually compared to 1.4 tively assess the accuracy of the first 50 patients
robotically. In addition, the variance using manual who underwent unilateral medial UKA with
instruments was 2.8 times greater than the roboti- robotic-assisted bone preparation with a dynami-
cally guided implantations ( p<0.0001). In the cor- cally referenced system. Complete pre- and post-
onal plane, the average error was 3.3  1.8 more operative records, pre- and postoperative CT scans,
varus using manual instruments compared to 0.1  and archived surgical plans were available for
2.4 when implanted robotically ( p<0.0001). A 20 knees (19 patients, 1 bilateral). RMS errors for
study by Lonner [13] retrospectively compared femoral component placement were within 1.6 mm
the postoperative radiographic alignment of the and 3.0 in all directions of the planned implant
tibial component with the preoperatively planned position, respectively. Average RMS errors for tib-
position in 31 consecutive patients who underwent ial component placement were within 1.6 mm and
UKA using robotic-arm assisted bone preparation 3.0 in all directions. Of note, this study was
and in 27 consecutive patients who underwent performed on patients receiving robotic-assisted
UKA using conventional manual instrumentation UKA in 2006–2007 with the TGS, the first gener-
to determine the error of bone preparation and ation robotic technology. The RIO robot currently
variance with each technique. Radiographically, available today is the third generation of the tech-
the RMS error of the posterior tibial slope was nology (Fig. 24).
3.1 when using manual techniques compared
with 1.9 when using robotic-arm assistance for
bone preparation. In addition, the variance using Accuracy of Joint Balancing
manual instruments was 2.6 times greater than the
robotically guided procedures. In the coronal Poehling et al. [15] conducted an investigation to
plane, the tibial components using manual instru- assess whether robotic-arm assisted UKA accu-
mentation exhibited an average error of 2.7  2.1 rately produced ligament tension according to an
111 Robotic-Arm Assisted Unicompartmental Knee Arthroplasty (MAKO) 1303

Fig. 24 Component
position accuracy has been
clinically validated to be
more reproducible and
precise than manual
techniques. X-rays show all
four FDA approved
procedures using the
MAKO robotic system

intraoperative balance plan devised before com- from six surgeons at six separate institutions.
ponent implantation. Fifty-two consecutive The average follow-up was 24  2.5 months.
robotic medial UKA cases were utilized for this Nine knees were reported as revised for an overall
study in which a dynamic ligament balancing of 2 year survivorship rate of 99 %. Ninety two
the knee was obtained under valgus stress prior to percent of patients reported feeling either “very
component implantation. This was then compared satisfied” or “satisfied.” This robotically guided
to final ligament balance with the components procedure shows improved early survivorship
cemented in place. The study found that 83 % of rates for UKA compared to what is currently
the cases were within 1 mm of the plan. Planned reported in implant registries and comparative
dynamic ligament balancing was found to be studies.
accurate to within 0.52 mm when compared to
the operative plan.
Discussion

Survivorship Since the beginning of partial knee replacement


in the 1950s and 1960s there have been several
Successful clinical outcomes following factors that we now know influence PKA out-
unicompartmental knee arthroplasty (UKA) comes. These include properly selected
depend on component positioning, soft tissue bal- patients, well designed implants correctly
ance, and overall limb alignment which can be sized, accurate alignment, and optimal balance
difficult to achieve using manual instrumentation. and tracking.
A multicenter study by Pearle et al. examined the Most surgeons will not perform enough PKAs
survivorship of robotically guided medial UKA to be proficient. The Mako robotic-arm assisted
coupled with a novel, anatomically designed partial knee replacement system can be highly
implant at 2 years postoperative [10]. A total of accurate and can allow the surgeon to achieve
959 patients (1,080 knees) in an initial series and good implant placement starting from the very
part of an IRB approved study underwent roboti- first case with proper training [2, 6, 8, 9, 11, 15,
cally guided surgery to receive a medial UKA 24, 25].
1304 F. Buechel Jr et al.

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