1.
olanzapine (Zyprexa)
DRUGS INDICATION/
CONTRAINDICATIONS
Generic name: Olanzapine is used to
olanzapine treat certain
mental/mood
Brand name: conditions (such
Zyprexa as schizophrenia, bipol
ar disorder). It may
also be used in
Classification: combination with
other medication to
Antipsychotic treat depression.
Dopaminergic blocker
CONGRATULATIONS:
- -Contraindicated with all
Dosage : ergy,to olanzapine,
5mg myelo proliferative
disorder s, severe CNS
- Route
depression, comatose
Oral states, lactation.
- of thirst related to CNS effects of
Use cautiously in elderly
or debilitated patients, or
with CV or
cerebrovascular disease,
dehydration, seizure
disorders, Alzheimer’s
disease, prostate
enlargement,
narrow-angle glaucoma,
history of paralytic ileus
or breast cancer,
pregnancy;
phenylketonuria (if using
orally disintegrating
tablets, contain
phenylalanine).
MODE OF ACTION SIDE/ADVERSE EFFECTS NURSING CONSIDERATION
Mechanism of action notCNS: Somnolence, dizziness, Assess for history of allergy to
fully understood; blocks nervousness, headache, olanzapine.
dopamine receptors in aka thisia, personality 2. Monitor Vital signs and record.
the brain, depresses the disorders, tardi ve Monitor for the many
RAS; blocks serotonin dyskinesia, neuroleptic possible drug interaction
receptor sites; malignant syndrome before beginning therapy.
anticholinergic, antihistaCV: Orthostatic hypotension, pEncourage patient
minic (H1), and alpha- eripheral edema,
to void before taking the drug
adrenergic blocking tachycardia to help decrease anti
activity may contribute toGI: Constipation, abdominal
cholinergic eff
some of its therapeutic pain ects of urinary
(and adverse) actions; Respiratory: Cough, pharyn gi
retention.
produces tis Take this drug exactly
fewer extrapyramidal Other: Fever, development of
as prescribed; do not change
effects than diabetes mellitus dose without consulting your
mostantipsychotics.
health care provider
Monitor elderly patients for
dehydration and institute
remedial measures promptly;
sedation and decreased sensation
drug can lead to dehydration.
7. Encourage patient to void
before taking the drug to help
decrease anticholinergic effec
ts of urinary retention
2. Flouxetine (motivest)

DRUG INDICATION MODE OF ACTION SIDE & ADVERSE EFFECT NURSING CONSIDERATION

Brand name: • Depression; OC • Inhibits CNS neuron • Hot flashes, palpitations, angina, − Monitor B, pulse every 4
Motivest disorders; bulimia uptake of serotonin, heart block, cerebral ischemia, MI, hours, if systolic BP
nervosa. but not of ventricular arrhythmias, drops
norepinephrine agitation, anxiety, nervousness, 20 mmhg, hold drug
Generic name: headache, insomnia, and notify physician;
Flouxetine abnormal dreams, take VS every 4 hours in
drowsiness, dizziness, tremor, patients with CV
fatigue, decreased libido, decreased disease.
Dosage: 20 concentration, seizures, − Monitor blood studies.
mg delusions, − Monitor hepatic studies.
hallucinations, coma. − Assess ECG
flattening of T
wave, bundle
branch block, AV block,
dysrhythmias in
cardiac pattern
− Monitor urinary
retention, constipation
− Assess appetite in
bulimia nervosa, weight
every day, increase
nutritious food in
diet.