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Lyme Disease
Lyme Disease
What is it:
Lyme disease is a bacterial disease caused by the bacterium Borrelia Burgdorferi. The Bacteria
are most commonly carried by Deer/ Blacklegged ticks. For Lyme disease to be transferred, it
has to be from tick to person, it takes about 36-48 hours for the tick to remain on the skin for the
transfusion. The tick becomes infected by feeding on deer, birds, and rodent the bacteria. People
who work in natural environments, are regularly in outdoor areas, or have pets are the most at
History:
The disease is named after the place of first suspected human contact with this disease. In Old
Lyme, Connecticut in 1975, a group of adults and children suffered from symptoms of swollen
knees, paralysis, skin rashes, headaches, and severe chronic fatigue. Two women in the area
started collecting notes, conducting research, and contacting scientists. They had gone through
the possibilities of it being caused by water or germs in the air. By cross-examining the notes,
they have noticed that patients have reported being bit by ticks in the region of Lyme. In 1980, a
scientist named Willy Burgdorfer discovered the spirochete bacteria. In honor of the discovery,
the bacterium was named after him as Borrelia Burgdorferi. A Lyme disease vaccine became
available in 1997 however was pulled from the market in 2001. (CT. Gov)
Symptoms:
Lyme disease symptoms have a broad variety of things they effect, some can be long term while
others only last a few days. Symptoms can include flat circular rash that is in a bullseyes shape,
fatigue, muscle aches, fever, loss of taste and smell, joint pain and swelling, headaches, swollen
lymph nodes.
Symptoms in children are slightly different as they include flu-like symptoms and psychological
issues. These psychological issues are associated with aggression, intense mood swings,
There are three most recognized stages of Lyme disease, early localized, early disseminated, and
late disseminated. Some symptoms overlap with other stages and people can be in the secondary
Stage 1: Early Localized – Symptoms start within 3-30 days after a bite from the tick. A rash can
occur known as Erythema Migrans, a bullseye rash. People who have light-coloured skin have a
solid red rash while people with dark-coloured skin can have a rash that resembles a bruise.
Symptoms of this stage can include, chills, fever, enlarged lymph nodes, sore throat, fatigue,
Stage 2: Early Disseminated – Symptoms or any indications of Lyme disease happen months
after the tick bite. They have a general unwell feeling throughout the whole body as well as a
rash, this is caused by the infection spreading. Symptoms of this stage include most from stage 1
but also include multiple erythema lesions and disturbances in heart rhythm. Neurological
conditions like tingling, numbness, facial + cranial nerve palsies, and meningitis. (GrepMed)
Stage 3: Late Disseminated – At this stage, many or all symptoms are similar to arthritis, and it is
common to be diagnosed with it instead of Lyme. Side effects include fatigue, memory
impairment, psychiatric disturbance, and chronic Lyme arthritis. Symptoms are hair loss,
seizures, stiffness, twitching, vision problems, hearing problems, dental problems, nerve
problems, and bladder issues. These symptoms can be long-lasting and affect your quality of life.
(Mexico, L)
Diagnosis of Lyme:
After someone has noticed a tick bite or tick present than has a bullseye rash present a visit to the
doctor should be made. When testing for Lyme disease testing during the first stage, localized
infection, it usually is not done. This is because the antibodies that are tested are not present yet,
usually people are given antibiotics to see if that solves the issue. Blood tests are the most
reliable a few weeks after the first infection because antibodies are more present. The enzyme-
linked immunosorbent assay (ELISA) is used to detect antibodies against spirochete bacteria.
The western blot is used to confirm the ELISA test, as it checks antibodies for specific B.
Burgdorferi proteins. Both the tests are run because they can both produce false negatives and
doing both it is ensuring that the patient does not have Lyme disease. Polymerase chain reaction
test (PCR) is used for evaluating patients who are experiencing persistent Lyme arthritis or
nervous system symptoms. The test is done by taking a needle and inserting it into a joint or
spine to extract joint/ cerebrospinal fluid, then running the test for antibodies. The PCR test is not
recommended unless necessary because of low sensitivity and a negative does not rule out the
disease. (Ldoadmin)
Treatment:
Lyme disease can easily be treated with antibiotics, later stages may require other treatments to
aid the long-term symptoms. Doxycycline, Amoxicillin, and Cefuroxime are commonly used for
adults and children, if being treated in the early localized or early disseminated stage 10-14 days
of antibiotics are typically given. Doxycycline is not used in the treatment of people who are
breastfeeding. Intravenous antibiotics are used for patients who have cardiac, or central nervous
Avoiding Lyme:
Lyme disease is a preventable disease when you take the right precautions. Avoid densely
wooded areas, and long grassy fields, from May to October. If you cannot avoid these areas then
wear brightly coloured long pants, and closed-toe shoes, making sure all long hair is properly
secured. Brightly coloured clothing helps because it is easier to spot if ticks may be on them. If
you have pets thoroughly check them for ticks and check yourself after being outdoors. When
inside shower as soon as possible to remove any unattached ticks. To kill ticks that might be
attached to clothing throw them in the dryer for 10 minutes on high heat. (Canada Gov)
After being treated some individuals, will still experience symptoms and effects. These
individuals are suffering from late or chronic Lyme. The effects can be life-lasting, some may
become less severe with treatments. Roughly around 10-20% of people that are treated for Lyme
disease experience post Lyme symptoms. It can affect mobility and cognitive abilities; it can take
months to years to gain these abilities back. Symptoms of chronic Lyme disease include arthritis
symptoms, fatigue, insomnia, difficulty concentrating/ remembering, speech problems, and even
trouble hearing.
Supermodel, Bella Hadid, is living with Lyme disease, she was diagnosed when she was 16 years
old. During her childhood, they grew up on a horse ranch where they were regularly in the
pasture, in the long grass. Starting at 14, Bella was suffering from joint pain, muscle cramps, and
numbness that was making her unable to ride horses. She had to give up her lifelong dream of
Olympic horseback riding because the symptoms she experienced affected her ability to ride. She
continues to suffer from the arthritis effects of Lyme disease now, as well as others, which affect
her daily activities. She says that once she was not able to get up for 6 days because of the pain
that she was in. Her memory was affected so severely that she had to stop driving, she stated in
an interview with evening standard magazine, "I was exhausted all the time. It affected my
memory so I suddenly wouldn't remember how to drive to Santa Monica from Malibu where I
lived." Chronic Lyme and its symptoms can affect the life quality of the inflicted, yet the CDC
does not recognize it as a disease. Bella Hadid is a 25-year-old who appears to be the picture of
health, she often refers to the disease as an invisible illness. An invisible illness is what it is,
there are no physical indicators that someone is suffering from it. Overall people who suffer from
chronic Lyme have no cure, simply treatments to manage the symptoms. (Gillespie, C)
early 2021 he had extremely bad joint problems and was constantly complaining of headaches.
He went to the hospital after 2 months of complaints about his problems when he collapsed
going up the stairs. After 6 weeks of testing, they finally ruled what he was suffering from to be
Lyme. He went on 28 days of antibiotic treatment because they suspected he got a tick bite 3
months prior to the diagnosis. About 3 months later he was complaining of constant ear ringing
and joint swelling, he was told he was 50% deaf in both ears even though before he had gotten
Lyme disease, he had perfect hearing. The doctor made the connection between post Lyme
disease and the symptoms he is facing now, there is no cure except having treatments to make
the symptoms less severe. He now has hearing aids and is taking arthritis medication to stop the
side effects. His family has also noticed recently that he has been forgetting basic short-term
things like not remembering his FOB for his car or leaving his wife at home and other locations.
Chronic Lyme affects small aspects of his life and is now dealing with this for the rest of his life.
(Reed, M)
Overview:
Lyme disease is a preventable disease that not only affects them at the time of infection but also
long-term. Side effects of this disease are still unknown and post-Lyme has no cure. Lyme
disease is on the rise and everyone no matter age, gender, or race is at risk if they live in North
America.
References:
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3 stages of Lyme disease early Lyme disease. GrepMed. (2019, April 29). Retrieved April 10,
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A brief history of Lyme disease in Connecticut. CT.gov. (n.d.). Retrieved May 25, 2022, from
https://portal.ct.gov/DPH/Epidemiology-and-Emerging-Infections/A-Brief-History-of-
Lyme-Disease-in-Connecticut
Giorgi, A. (2021, August 18). What you need to know about early disseminated Lyme disease
https://www.healthline.com/health/lyme-disease-early-disseminated
History of Lyme disease. Bay Area Lyme Foundation. (2022, May 9). Retrieved May 30, 2022,
from https://www.bayarealyme.org/about-lyme/history-lyme-disease/
Lyme Basics: Canlyme - Canadian Lyme disease foundation. CanLyme. (2021, February 16).
Mexico, L. (2021, March 17). Late-stage Lyme disease: Symptoms and treatment. Lyme Mexico
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Schoen, R. T. (2020). Challenges in the diagnosis and treatment of Lyme disease. Current
Team, T. H. E. (2019, November 13). Everything you need to know about Lyme disease.
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What are the signs and symptoms of stage 3 (chronic) Lyme disease? Latest Medical News,
Clinical Trials, Guidelines - Today on Medscape. (2021, April 27). Retrieved April 6,
symptoms-of-stage-3-chronic-lyme-disease?reg=1
Reed, M. (2022, April 5). Bill Macintosh - My Life with Lyme. personal.
Johnson, K. O., Nelder, M. P., Russell, C., Li, Y., Badiani, T., Sander, B., Sider, D., & Patel, S.
L., Chen, T., Li, L., Li, B., Dong, Y., Luo, S., Zhou, G., Liu, A., & Bao, F. (2021). Forty
years of evidence on the efficacy and safety of oral and injectable antibiotics for treating
9(3). https://doi.org/10.1128/spectrum.00761-21
Late Lyme disease. Ada. (n.d.). Retrieved March 25, 2022, from https://ada.com/conditions/late-
lyme-disease/
Bonner, M. (2021, November 1). What you need to know about Bella Hadid's Lyme disease
https://www.cosmopolitan.com/entertainment/a21286398/bella-hadid-lyme-disease/
Bella Hadid shares the "truth" about debilitating Lyme disease symptoms. E! Online. (2020,
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Gillespie, C. (2020, August 27). Bella Hadid struggles with at least 10 of these Lyme disease
side effects every single day. Health. Retrieved May 1, 2022, from
https://www.health.com/condition/lyme-disease/lyme-disease-symptoms-bella-hadid
https://www.lymedisease.org/lyme-basics/lyme-disease/treatment/