MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING

DRUG SIDE EFFECTS

ACTION OR PURPOSE S REACTIONS RESPONSIBILITIES
Generic Cefuroxime binds It is effective for Hypersensitivity to GI: Large doses can Assessment
Name: to one or more of the treatment of cephalosporins related Diarrhea, nausea, cause cerebral
Cefuroxime the penicillin- penicillinase- to antibiotics; antibiotic- associated irritation and History:  Hepatic and renal
binding proteins producing Neisseria pregnancy (category B), colitis convulsions; impairment, lactation,
(PBPs) which gonorrhea (PPNG). lactation. nausea, vomiting, pregnancy
inhibits the final Effectively treats Skin: diarrhea, GI Physical: Skin status,
Brand Name: Rash, pruritus, urticaria LFTs, renal function tests,
transpeptidation bone and joint disturbances;
Danoxime culture of affected area,
step of infections, erythema
peptidoglycan bronchitis, Urogenital: multiforme, sensitivity tests
synthesis in meningitis, Increased serum Stevens-Johnson -Culture infection and
bacterial cell wall, gonorrhea, otitis creatinine and BUN, syndrome, arrange for sensitivity
thus inhibiting media, decreased creatinine epidermal tests before and during
Classification: biosynthesis and pharyngitis/tonsiliti clearance necrolysis. therapy if expected
Antibiotic, arresting cell wall s, sinusitis, lower Potentially response is not seen.
Cephalosporin assembly resulting respiratory tract Hemat: Fatal: Anaphylaxis, -Have vitamin K available
(second in bacterial cell infections, skin and Hemolytic anemia nephrotoxicity, in case
generation) death. soft tissue pseudomembranou hypoprothrombinemia
infections, urinary MISC: s colitis. occurs.
Date, Route, -Discontinue if
tract infections, Anaphylaxis
Timing: hypersensitivity reaction
340 mg IVTT and is used for
surgical occurs.
Q8H ANST -Take full course of
prophylaxis,
reducing or therapy even if you are
eliminating feeling better.
infection. -This drug is specific for
this infection and should
not be used to self-treat
other problems.
-Report severe diarrhea
with blood, pus, or mucus;
 MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING
DRUG SIDE EFFECTS
ACTION OR PURPOSE S REACTIONS RESPONSIBILITIES

rash; difficulty breathing;

unusual tiredness, fatigue;
unusual bleeding or
Generic It relaxes the Quick relief of -Hypersensitivity to CNS: Restlessness, -Fast, irregular, -Check and verify with
Name: smooth muscles of bronchospasm salbutamol apprehension, anxiety, pounding, or doctor’s order and Kardex.
Salbutamol the bronchioles induced through -Tachyarrhythmias and fear, CNS stimulation, racing heartbeat or -Observe rights
allowing maximum both exercise and tachycardia caused by vertigo, headache, pulse in medication administrati
passage of air. It physiological digitalis intoxication weakness, tremors, on such as giving the right
decreases alterations. Also -Cardiac disease drowsiness, insomnia, -shakiness in the drug to the right patient
Brand Name: legs, arms, hands, using the right route and
intracellular used to control and including coronary hyperactivity, malaise
calcium which will prevent reversible insufficiency, a history CV: Cardiac arrhythmias, or feet at the right time.
relax the smooth airway obstruction of stroke, coronary palpitations, tachycardia, -trembling or -Monitor ECG, serum
muscles of the caused by artery disease and chest pain, hypertension shaking of the electrolytes and thyroid
lungs by bronchial asthma, cardiac arrhythmias EENT: dry and irritated hands or feet function test results.
mobilizing kinase chronic obstructive -Excess inhalers use nose and throat with -Administer accurately
Classification: through activation pulmonary which may lead to inhaled form, nasal because adverse reactions
Bronchodilato of cyclic-3’5’- diseases such as tolerance and congestion, epistaxis, and tolerance might occur.
r, Adrenergic adenosine emphysema and paradoxical hoarseness -Raise side rails up
monophosphate chronic bronchitis bronchospasm disease Dermatologic: Sweating, because client might be
(cAMP). as well as other pallor, flushing restless and drowsy
 MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING
DRUG SIDE EFFECTS
ACTION OR PURPOSE S REACTIONS RESPONSIBILITIES
Date, Route,
Timing:
Q15mins x 3
doses the
Q4H

obstructive GI: Nausea, vomiting, because of this drug.

pulmonary heartburn, unusual or -Keep room well-lit and
diseases. bad taste in the mouth see to it that client has a
Inhalation: Metabolic: hypokalemia person with him closely in
treatment of acute Musculoskeletal: musc case of vertigo.
attacks of le cramps -Assess lung sounds, PR
bronchospasm. Respiratory: Respiratory and BP before drug
difficulties, pulmonary administration and during
edema, coughing, peak of medication.
bronchospasm, -Assess pulse for rhythm.
paradoxical airway -Provide oral care or let
resistance with repeated, patient gurgle after
excessive use of inhalation to get rid of the
inhalation preparations, unpleasant aftertaste of
 MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING
DRUG SIDE EFFECTS
ACTION OR PURPOSE S REACTIONS RESPONSIBILITIES
Generic Hydrocortisone is -Replacement Viral/fungal infections, -blurred vision, tunnel Sodium and fluid -Space multiple doses
Name: a corticosteroid therapy in adrenal tubercular or syphilitic vision, eye pain, or retention. evenly throughout the
Hydrocortison used for its anti- cortical lesions, bacterial seeing halos around Potassium and day.
e inflammatory and insufficiency infections unless used in lights; calcium depletion. -Do not give IM injections
immunosuppressiv -Allergic states— conjunction with -muscle weakness, loss Muscle wasting, if patient has
e effects. Its anti- severe or appropriate of muscle mass. weakness, thrombocytopenic
Brand Name:
inflammatory incapacitating chemotherapy. -new or unusual pain in osteoporosis. GI purpura.
Hydrocortone
action is due to allergic conditions your joints, bones, or disturbances and -Rotate sites of IM
phosphate
the suppression of -Hypercalcemia muscles. bleeding. repository injections to
migration of associated with -severe headaches, Increased appetite avoid local atrophy.
polymorphonuclea cancer ringing in your ears, pain and delayed -Use minimal doses for
r leukocytes and -Hematologic behind your eyes. wound healing. minimal duration to
Classification: reversal of disorders— -unusual changes in Bruising, striae, minimize adverse effects.
Corticosteroid increased capillary thrombocytopenic mood or behavior. hirsutism, acne, -Taper doses when
(short acting), permeability. It purpura, -a seizure. flushing. Raised discontinuing high-dose or
Glucocorticoid may also be used erythroblastopenia -fluid retention-- intracranial long-term therapy.
, Adrenal as replacement -Trichinosis with shortness of breath pressure, -Arrange for increased
cortical therapy in neurologic or (even while lying down), headache, dosage when patient is
steroid adrenocortical myocardial swelling, rapid weight depression, subject to unusual stress.
hormone insufficiency. involvement gain (especially in your psychosis, -Ensure that adequate
Date, Route, -Ulcerative colitis, face and midsection); menstrual amount of Ca2+ is taken if
Timing: acute -new signs of infection-- irregularities. prolonged administration
40 mg IVTT exacerbations of such as fever, chills, Hyperglycemia, of steroids.
Q6H MS, and palliation cough, trouble breathing, glycosuria, DM, -Use alternate-day
in some leukemias sores in your mouth or obesity, moon- maintenance therapy with
and lymphomas on your skin, diarrhea, or face, buffalo short-acting
-Intra-articular or burning when you hump. Suppression corticosteroids whenever
soft-tissue urinate; of pituitary- possible.
administration: -increased adrenal adrenocortical -Do not give live virus
 MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING
DRUG SIDE EFFECTS
ACTION OR PURPOSE S REACTIONS RESPONSIBILITIES
Arthritis, psoriatic gland hormones--slow system. Growth vaccines with
plaques wound healing, skin retardation in child immunosuppressive doses
-Retention enema: discoloration, thinning (prolonged of hydrocortisone.
For ulcerative skin, increased body therapy). -Provide antacids between
colitis, proctitis hair, tiredness, Increased meals to help avoid peptic
-Dermatologic menstrual changes, susceptibility for ulcer.
preparations: To sexual changes. infection. Topical
relieve use: Dermal
inflammatory and atrophy, local
pruritic irritation,
manifestations of folliculitis,
dermatoses that hypertrichosis.
are steroid Inhaled
responsive corticosteroids:
-Anorectal cream, May cause
suppositories: To hoarseness,
relieve discomfort candidiasis of
of hemorrhoids and mouth and throat.
perianal itching or Topical application
irritation to the eye: Can
produce corneal
ulcers, raised IOP
and reduced visual
function.
Intralesional
injection: Local
hypopigmentation
of deeply
pigmented skin.
 MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING
DRUG SIDE EFFECTS
ACTION OR PURPOSE S REACTIONS RESPONSIBILITIES

Intra-articular
injection: Joint
damage, fibrosis
Generic Decreases fever Relief of mild-to- -Hypersensitivity Stimulation, drowsiness, Thrombocytopenia Assess patient’s fever or
Name: by inhibiting the moderate pain; nausea, vomiting, , anaphylaxis, pain: type of pain,
Paracetamol effects of treatment of fever. -intolerance to abdominal pain, cutaneous location, intensity,
pyrogens on the tartrazine (yellow dye hepatotoxicity, hepatic hypersensitivity duration, temperature,
hypothalamus #5), alcohol, table seizure (overdose, Renal reactions including and diaphoresis.
heat regulating sugar, saccharin failure (high, prolonged skin rashes,
Brand Name: Assess allergic reactions:
centers & by a doses), leucopenia, angioedema &
hypothalamic -Contraindicated with neutropenia, hemolytic Stevens-Johnson rash, urticaria; if these
action leading to allergy to anemia (long term use) syndrome, occur, drug may have to
sweating & acetaminophen thrombocytopenia, bronchospasm in be discontinued.
vasodilatation. pancytopenia, rash, patients sensitive
urticaria, to aspirin & other Teach patient to recognize
Classification: Relieves pain by hypersensitivity, NSAIDs, hepatic signs of chronic overdose:
Analgesic inhibiting cyanosis, anemia, dysfunction. bleeding, bruising,
Muscle prostaglandin jaundice, CNS, malaise, fever, sore
relaxants synthesis at the stimulation, delirium throat.
CNS but does not followed by vascular
 MECHANISM OF INDICATIONS CONTRAINDICATION ADVERSE NURSING
DRUG SIDE EFFECTS
ACTION OR PURPOSE S REACTIONS RESPONSIBILITIES
Date, Route,
Timing:
1.2 ml PO
Q4H PRN or
PCM 100 mg
IVTT Q4H for
Temp > 38ºC
have anti- collapse, convulsions, Tell patient to notify
inflammatory coma, death. prescriber for pain/ fever
action because of lasting for more than 3
its minimal effect days.
on peripheral
prostaglandin
synthesis.