ORGANIC CHEMISTRY

Chapter 2: ELECTRONIC & STERIC EFFECTS

This homework has been made by
Nguyen Minh Thuan_2114937_L01_CQ_HK221.

1
Homework Acidity: (8) > (7) > (1) > (6) > (4) > (5) > (3) > (2)
Compare acidity of following compounds:

(-I, -C,
moderate) (-I < +C) (+H strong, +I)

(-I, -C,
(+H weak, +I) (-I > +C) (-I, -C, strongest)
strong)
(Basicity: (3) > (7) > (8) > (1) > (4) > (10) > (9) > (12) > (2) > (11) > (13)
Homework > (5) > (6)
Compare basicity of following compounds:
(2x -C) (3x -C)

(no
-Phe)
(+H,
(-I, -C, +I)
moderate)

(-I < +C) (-I

(-I < +C weak) (-I, -C, (-I > +C) (-I, -C,
but +C strong) stronger
stronger than (1): N bậc 3 tính base kém hơn N bậc 1, than
-OCOCH3) đồng thời N bậc 3 này liên hợp +C kém. -CN)