Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects Nursing Responsibilities

Generic Name Pharmacologic Blocks histamine H1- General Indication: Lower respiratory diseases such CNS: Dose-related drowsiness Before:
Diphenhydramine Class: receptors on effector cells Relief of symptoms as asthma attacks Sedation  Identify patient
Hydrochloride Second generation of the GI tract, blood associated with perennial Disrupted coordination  Determine why the
cephalosphorin vessels and respiratory and seasonal allergic medication was
Trade Name tract. It also causes rhinitis; vasomotor Patients taking MAOIs CV: Hypotension Palpitations ordered and assess
Benadryl Therapeutic Class: sedation and has some rhinitis; allergic Tachycardia, bradycardia symptoms that
Antihistamine, anticholinergic action. conjunctivitis; mild, Hypersensitivity apply to the
Patient's Dose antitussive uncomplicated urticaria RESP: Thickening of bronchial patient.
50 mg IVTT Pharmacokinetics: and angioedema; Narrow-angle glaucoma secretions  Do not confuse
amelioration of allergic Benadryl with
Maximum Dose Absorption: Well absorbed reactions to blood or Benylin,
50 mg/ml after oral or IM plasma;dermatographism; GI: Dry mouth and throat
desipramine, or
administration but 40-60% adjunctive therapy in with
Minimum Dose of an oral dose reaches anaphylactic reactions dimenhydrinate.
10 mg/ml systemic circulation due to - Active and  Perform
first-pass metabolism prophylactic handwashing.
Availability treatment of  Assess for allergies
10-50 mg IVTT Distribution: Widely motion sickness and
distributed - Nighttime sleep hypersensitivity.
Route aid
IV Metabolism and Excretion: - Parkinsonism in During:
95% metabolized by the the elderly  Explain to the
liver. intolerant of patient the function
more potent of this drug.
Half-life: 2.4-7 hrs drugs, for milder  Monitor site
Onset: 15-60 min forms of the frequently for
Peak: 2-4 hr disorder in other thrombophlebitis
Duration: 4-8 hr age groups, and (pain, redness, and
in combination swelling).
with centrally After:
acting
 Caution patient to
anticholinergic
avoid activities
antiparkinsonian
requiring alertness
drugs
until response to
drug is known.
Patient's Indication:
 Monitor carefully,
Sedation for the patient
assess for
who is scheduled for
confusion,
surgery
delirium, other
anticholinergic side
effects and fall
risk.
  Institute measures
to prevent falls.

Doenges,M.E,Moorhouse Doenges,M.E,Moorho Doenges,M.E,Moorhouse Doenges,M.E,Moorhouse Doenges,M.E,Moorhouse Doenges,M.E,Moorhouse Doenges,M.E,Moorhouse

M.F.,&Murr,A.C.(2010) use M.F.,&Murr,A.C. M.F.,&Murr,A.C.(2010) M.F.,&Murr,A.C.(2010) M.F.,&Murr,A.C.(2010) Nurses M.F.,&Murr,A.C.(2010) M.F.,&Murr,A.C.(2010)
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Pennsylvania Ed.FA:Davis Pennsylvania Pennsylvania Pennsylvania Pennsylvania
Company:
Pennsylvania