CRITERIA:

DAVAO DOCTORS COLLEGE Content and organization 40%

General Malvar St., Davao City Analysis 40%
Nursing Program Neatness and promptness 10%
Reference 10%
DRUG STUDY TOTAL 100%

Name of Patient: X Date of Admission: Room:

Age: 51 Sex: male Civil Status: N/A

CLASSIFICATION /
DRUG NAME
MECHANISM OF ACTION
Aspirin, an acetylated
salicylate (acetylsalicylic
BRAND NAME: ASPIRIN
acid), is classified among the colds, minor pain of arthritis, to NSAIDs and in patients
GENERIC nonsteroidal
Acetylsalicylic acid antiinflammatory drugs
(NSAIDs). These agents
reduce the signs and
DOSAGE: 80mg 1 tab.
symptoms of inflammation
and exhibit a broad range of
pharmacologic activities,
ROUTE: O.D. including analgesic,
antipyretic, and antiplatelet
properties.
Aspirin works by irreversibly
FREQUENCY: inhibiting the enzyme cyclo-
oxygenase (COX-1) which is
required to make the
precursors of thromboxane
within platelets. This reduces
thromboxane synthesis.
Thromboxane is required to
facilitate platelet aggregation
and to stimulate further
platelet activation.
INDICATION CONTRAINDICATIONS
Aspirin is indicated for • Contraindications:
temporary relief of Aspirin is contraindicated in
headache, pain and fever of patients with known allergy
muscle pain, menstrual pain, with asthma, rhinitis, and
and toothache. nasal polyps. It may cause
anaphylaxis, laryngeal
edema, severe urticaria,
angioedema, or
bronchospasm (asthma)
NURSING
SIDE/ADVERSE
RESPONSIBILITY
EFFECTS
• rash, • Check and verify with
• gastrointestinal doctor’s order
ulcerations, • Observe rights in
•
abdominal pain, medication
• upset stomach, administration such as
• heartburn, giving the right drug to
• drowsiness, the right patient using
•
headache, the right route and at
• cramping, the right time.
• nausea, • Assess skin color and
• gastritis, and presence of lesions as
• bleeding this may indicate
hepatotoxicity, allergy,
ADVERSE bleeding, and other
EFFECTS complications.
• Assess patient’s
Acute aspirin orientation to time and
toxicity: Respiratory place as the drug may
alkalosis, hyperpnea, cause dizziness and
confusion.
tachypnea,
• Give drug with food or
hemorrhage,
after meal if GI upset
excitement,
occurs.
confusion, asterixis,
• To reduce the risk of
pulmonary edema,
the tablet lodging in
seizures, tetany, the esophagus, give
metabolic acidosis, drug with full glass of
fever, coma, CV water.
collapse, renal and • Ensure that patient
respiratory failure

REFERENCES:
https://www.getreliefresponsib
lyprofessional.com/aspirin-
contraindications-interactions
https://www.uspharmaci
st.com/article/benefits-
and-risks-of-daily-aspirin-
use
https://www.uptodate.co
m/contents/aspirin-
mechanism-of-action-
major-toxicities-and-use-
in-rheumatic-diseases
(dose related, 20–25 g does not crush and
in adults, 4 g in chew tablets as well as
children) sustained release
preparations to
prevent losing drug’s
Aspirin intolerance:
effectivity.
Exacerbation of
• If aspirin has vinegar-
bronchospasm,
like odor, do not use
rhinitis (with nasal
polyps, asthma, and dispose.
rhinitis) • In case of overdose,
institute emergency
procedures and
GI: Nausea,
dyspepsia, heartburn, prepare equipment’s
for gastric lavage,
epigastric discomfort,
induction of emesis,
anorexia,
and activated charcoal.
hepatotoxicity
• Continue monitoring
clotting factors,
Hematologic: Occult bleeding time, liver and
blood loss, renal function tests for
hemostatic defects long-term drug
therapy.
Hypersensitivity: • Observe patient for
Anaphylactoid signs and symptoms of
reactions to bleeding such as easy
anaphylactic shock bruising, bleeding in
the gums, and
Salicylism: Dizziness, nosebleeds.
tinnitus, difficulty • Monitor vital signs.
hearing, nausea, • Raise side rails up to
vomiting, diarrhea, ensure patient’s safety.
mental confusion, • Monitor for signs and
lassitude (dose symptoms of drug
related) allergy such as difficulty
of breathing, pruritus,
and rashes.
• Provide a room
environment conducive
for resting.
LAURENTE, PAOLO CHEL E.
Name of Student