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Jurnal Terapi Musik 2
Jurnal Terapi Musik 2
Jurnal Terapi Musik 2
Summary
Aim: To test whether postoperative music listening reduces morphine
consumption and influence pain, distress, and anxiety after day
surgery and to describe the experience of postoperative music
listening in school-aged children who had undergone day surgery.
Background: Music medicine has been proposed to reduce distress,
anxiety, and pain. There has been no other study that evaluates effects
of music medicine (MusiCure) in children after minor surgery.
Methods: Numbers of participants who required analgesics, individ-
ual doses, objective pain scores (Face, Legs, Activity, Cry, Consol-
ability [FLACC]), vital signs, and administration of anti-emetics were
documented during postoperative recovery stay. Self-reported pain
(Coloured Analogue Scale [CAS]), distress (Facial Affective Scale
[FAS]), and anxiety (short State-Trait Anxiety Inventory [STAI]) were
recorded before and after surgery. In conjunction with the completed
intervention semi-structured qualitative interviews were conducted.
Results: Data were recorded from 80 children aged 7–16. Forty
participants were randomized to music medicine and another 40
participants to a control group. We found evidence that children in the
music group received less morphine in the postoperative care unit,
1 ⁄ 40 compared to 9 ⁄ 40 in the control group. Children’s individual
FAS scores were reduced but no other significant differences between
the two groups concerning FAS, CAS, FLACC, short STAI, and vital
signs were shown. Children experienced the music as ‘calming and
relaxing.’
Conclusions: Music medicine reduced the requirement of morphine
and decreased the distress after minor surgery but did not else
influence the postoperative care.
Correspondence to: Stefan Nilsson, Department of Paediatric Anaesthesia and Intensive Care Unit, The Queen Silvia Children’s Hospital,
Sahlgrenska University Hospital, 416 85 Göteborg, Sweden (email: stefan.r.nilsson@vgregion.se).
used for rating the level of distress by marking one Data analysis
of nine faces presented in an ordered sequence from
Quantitative data
least (0.04) to most distressed (0.97) (14). The
Calculation of sample size was based on expected
children also filled in the short form of State-Trait
self-reported pain scores and morphine consump-
Anxiety Inventory (STAI) (17) in conjunction with
tion in an earlier published study of music medicine
their first and last self-report of the CAS and the
in adults (5). With a difference of one step between
FAS. This instrument is a short form of the STAI
the CAS scores in the intervention group and control
with six questions. The range for the short STAI is
group, a standard deviation (SD) of 1.5 and a power
6–24 points, six points signifies no anxiety and 24
of 0.80 at least 36 participants were needed. For a
points signifies the highest level of anxiety. The
difference in morphine consumption even a lower
original STAI has been widely used to evaluate
number was needed. It was decided that each group
anxiety in studies of music in conjunction with
contained 40 participants. Statistical significance was
anesthesia (3). The STAI was originally designed for
set at P < 0.05. The risk ratio (RR), 95% confidence
adults but has earlier been used in adolescents for
intervals (CI), and absolute risk reduction for mor-
the evaluation of music in conjunction with medical
phine consumption was calculated. Chi-square test
procedures (18).
was used to compare numbers of participants who
needed morphine and anti-emetics and to analyze
Observations the telephone inquiry. Mann–Whitney U test was
chosen to analyze differences between the study
All observations were made by one researcher, and
groups in self-reported parameters and observed
two experienced nurses all of whom were familiar
pain and Wilcoxon signed rank test for comparing
with the pain scales. The nurses observed the
changes before and after the procedures. Demo-
children in the PACU and recorded FLACC scores
graphic data, administered medication, heart rate,
every 15-min during 45 min and before the child left
and oxygen saturation were analyzed using t-test.
the PACU. The FLACC contains five categories, each
of which is scored from 0 to two providing a total
Qualitative data
score ranging from 0 to 10 (15,16). Respiratory rate,
All interviews were read and analyzed by using a
heart rate, and saturation were also recorded every
qualitative content analysis, and the texts were
15-min during the 45 min.
selected to condensed meaning units in an organized
manner (19). Each time a condensed meaning unit
Interviews arose in the texts, it was counted to value the
magnitude. This step follows recommendations for
Following completion of the intervention, semi-
combining quantitative and qualitative methods in
structured qualitative interviews, based on an inter-
content analysis (20). The meaning units were
view guide, were conducted with the 40 children
subsequently abstracted to categories and eventually
in the intervention group. The interviews were
abstracted to themes (19).
recorded using an MP3 player and transcribed
verbatim. In addition, the child was asked if he or
she would like to use music during any later need Results
for surgery.
Quantitative data
The day after the surgery a researcher asked all
children two questions by telephone, i.e., ‘What did This study was conducted between October 2007
you think about the postoperative care?’ and ‘How and late October 2008. Ninety-two children were
was your sleep the night after the visit on the consecutively asked for participation, 12 children
pediatric day surgery unit?’ These two questions declined to participate, and data were finally
had four standardized answers, i.e., bad, not so recorded on 80 children aged 7–16, ASA I–II
good, good, or very good. If the answer was bad or (Figure 1).
not so good the researcher asked about the reason Demographic data, analgesics and anti-emetics
for this answer. administered pre- and peroperatively, and type of
Excluded (n = 12)
Enrollment
Not meeting inclusion criteria (n = 0)
Did not receive allocated intervention (n = 0) Did not receive allocated intervention (n = 0)
Follow-Up Did not the day after the surgery answer the
telephone call
Figure 1
The consort E-flowchart.
surgery are presented in Table 1. No substantial the control group (P < 0.05). Pain scores >4 were
differences between groups were found. Total intra- found in five children in the music group and in
venous anesthesia with propofol and alfentanil was seven children in the control group in PACU. Four
provided in all cases except one where thiopentone children with pain scores above four in the music
and sevoflurane was used. Propofol was adminis- group abstained from morphine compared to no one
tered for induction in 74 cases and inhalation with in the control group. Two children in the control
sevoflurane in six cases. group reported pain and received morphine but
Significantly, fewer children in the music group were not awake enough to use the CAS, and the
(1 ⁄ 40) compared to the control group (9 ⁄ 40) received FLACC did not indicate pain. Three children in the
morphine in the PACU (P < 0.05). The RR was 0.11 control group required anti-emetics after morphine
(95% CI 0.015–0.828), and the absolute risk reduction administration. No statistically significant difference
was 20%. Total morphine administration was sig- in medication between the study groups was found
nificantly lower in the music group 4 mg (mean 0.10, during the 1-h observation on the ward until the last
SD 0.63) compared to 30.5 mg (mean 0.76, SD 1.58) in scoring of the CAS, the FAS and the short STAI. In
Table 1 Table 2
Description of participants and administration of pre- and Scores of CAS, FAS and short STAI (median, range) and P-values
perioperative medication for comparisons between groups
thought it was beautiful with music, which gave The qualitative interviews indicated that the
protection from other environmental noise, ‘You children preferred to select and participate in the
woke up calm and it was beautiful, nicer than listen decisions of music medicine. Similar results have
to babies that cry I think.’ The category ‘You should been found in children using Virtual Reality (24).
be able to select music even if calm music probably The children in our study experienced calmness and
is preferable’ indicated that children preferred to relaxation with the researchers selected music as
select music and one participant said ‘I do not adults have reported with MusiCure (4,8). These
believe that you would like to use your own music, results showed that this music style regardless of
but it had probably been better if you got the age is useful postoperatively for relaxation and
possibility to select music.’ The theme was finally calmness.
reflected in the category ‘The music made the Disturbed night sleep was found in 19 ⁄ 79
technical equipment negligible and not disturbing.’ participants (24%) related to pain compared to
The participants thought the equipment was com- 23 ⁄ 175 (13%) in an earlier study in the same unit
fortable and did not disturb them. One participant (25).
said ‘You do not notice the equipment and you are This study has some methodological consider-
able to communicate while you listen’. ations. We did not collect interviews in the control
group to compare with the interviews of children
using music medicine. The short STAI is not
Discussion
validated in children but is easy to use. The short
Morphine use was lower in the music group than in form may be preferable compared to original STAI
the control group during PACU stay. The reduction with a long checklist and many items, which
in morphine was consistent with the qualitative sometimes become a hindrance (17). This study
interviews where music medicine seems to be a did not use a blinded design for the postoperative
useful complement for postoperative well-being. In period, which might lead to a sense of missing
adults, fewer requests for opioids have been re- intervention in the control group. It could influence
ported with music medicine. In that study pain participants and staff’s behaviour regarding mor-
scores decreased with music but no differences were phine administration but structured guidelines
found for anxiety or heart rate (21). In a systematic were used in order to minimize this effect. It is
review, music was also found to have opioid difficult to make a study design blinded with a
reducing effects (22). The clinical importance for nonpharmacological method because it is often
reduction in postoperative nausea and vomit impossible to create a trustworthy placebo. For that
(PONV) is unclear. In our study, PONV were not reason, it could even better to have an open study;
recorded but actually three children in the control a blinded study with a not trustworthy placebo
group required ondansetron after morphine may give false conclusions.
administration.
Children decreased their individual FAS scores in
Conclusion
PACU compared to preoperatively with music medi-
cine. We did not find any other important differences Music medicine reduced the requirement of mor-
in pain, distress, or anxiety between the groups with phine and children’s distress scores (FAS) after
and without postoperative music medicine. Music minor surgery but did not change observations
seems to act as a distracter and actually makes the (FLACC and vital signs) or self-reported pain
child to endure the amount of perceived pain. (CAS) and anxiety (short STAI). Children experi-
An increased sound level in the staff’s working enced the music as ‘calming and relaxing.’
environment could be an adverse effect of music
(23). In our study, the music was individually
Acknowledgments
administered and the participants with music med-
icine appreciated this environmental exclusion. We thank all the children who participated in the
However, this might also exclude some communi- study, generously gave their time and shared their
cation between the child and the staff. experiences. We would also like to thank Britt-Marie
Karlsson and Eva Norling for data collection. Finally, 11 Chetta HD. The effect of music and desensitization on pre-
operative anxiety in children. J Music Ther 1981; 18(2): 74–87.
we would like to thank Per Thorgaard for sharing his
12 Kain ZN, Wang SM, Mayes LC et al. Sensory stimuli and
knowledge about postoperative music. The Ebba anxiety in children undergoing surgery: a randomized,
Danelius Foundation and the Wilhelm and Martina controlled trial. Anesth Analg 2001; 92(4): 897–903.
Lundgrens Foundation funded this research project. 13 Hatem TP, Lira PI, Mattos SS. The therapeutic effects of music
in children following cardiac surgery. J Pediatr (Rio J) 2006;
82(3): 186–192.
14 McGrath PA, Seifert CE, Speechley KN et al. A new analogue
Potential conflicts of interest scale for assessing children’s pain: an initial validation study.
Pain 1996; 64(3): 435–443.
All authors declare that they have no conflicts of 15 Merkel SI, Voepel-Lewis T, Shayevitz JR et al. The FLACC: a
interest. behavioral scale for scoring postoperative pain in young chil-
dren. Pediatr Nurs 1997; 23(3): 293–297.
16 Nilsson S, Finnstrom B, Kokinsky E. The FLACC behavioral
References scale for procedural pain assessment in children aged
5–16 years. Pediatr Anesth 2008; 18(8): 767–774.
1 Blount RL, Piira T, Cohen LL et al. Pediatric procedural pain.
17 Marteau TM, Bekker H. The development of a six-item short-
Behav Modif 2006; 30(1): 24–49.
form of the state scale of the Spielberger State-Trait Anxiety
2 Dileo C, Bradt J. Medical Music Therapy: a Meta-analysis &
Inventory (STAI). Br J Clin Psychol 1992; 31(Pt 3): 301–306.
Agenda for Future Research. Cherry Hill, NJ: Jeffrey Books, 2005.
18 Rickert VI, Kozlowski KJ, Warren AM et al. Adolescents and
3 Nilsson U. The anxiety- and pain-reducing effects of music
colposcopy: the use of different procedures to reduce anxiety.
interventions: a systematic review. AORN J 2008; 87(4): 780–
Am J Obstet Gynecol 1994; 170(2): 504–508.
807.
19 Graneheim UH, Lundman B. Qualitative content analysis in
4 Nilsson U. Soothing music can increase oxytocin levels during
nursing research: concepts, procedures and measures to
bed rest after open-heart surgery; a randomized control trial.
achieve trustworthiness. Nurse Educ Today 2004; 24(2): 105–112.
J Clin Nurs 2009; 18(15): 2153–2161.
20 Krippendorff K. Content Analysis. An Introduction to Its Meth-
5 Nilsson U, Unosson M, Rawal N. Stress reduction and anal-
odology. London: Sage Publications, 2004.
gesia in patients exposed to calming music postoperatively: a
21 Ebneshahidi A, Mohseni M. The effect of patient-selected
randomized controlled trial. Eur J Anaesthesiol 2005; 22(2):
music on early postoperative pain, anxiety, and hemodynamic
96–102.
profile in cesarean section surgery. J Altern Complement Med
6 Cooke M, Chaboyer W, Schluter P et al. The effect of music on
2008; 14(7): 827–831.
preoperative anxiety in day surgery. J Adv Nurs 2005; 52(1):
22 Cepeda MS, Carr DB, Lau J et al. Music for pain relief. Cochrane
47–55.
Database Syst Rev 2006; 2: CD004843.
7 Leardi S, Pietroletti R, Angeloni G et al. Randomized clinical
23 Thorgaard P, Ertmann E, Hansen V et al. Designed sound and
trial examining the effect of music therapy in stress response to
music environment in postanaesthesia care units – a multi-
day surgery. Br J Surg 2007; 94(8): 943–947.
centre study of patients and staff. Intensive Crit Care Nurs 2005;
8 Nilsson U. The effect of music intervention in stress response
21(4): 220–225.
to cardiac surgery in a randomized clinical trial. Heart Lung
24 Nilsson S, Finnström B, Kokinsky E et al. The use of Virtual
2009; 38: 201–207.
Reality for needle-related procedural pain and distress in
9 Klassen JA, Liang Y, Tjosvold L et al. Music for pain and
children and adolescents in a paediatric oncology unit. Eur J
anxiety in children undergoing medical procedures: a sys-
Oncol Nurs 2009; 13(2): 102–109.
tematic review of randomized controlled trials. Ambul Pediatr
25 Kokinsky E, Thornberg E, Ostlund AL et al. Postoperative
2008; 8(2): 117–128.
comfort in paediatric outpatient surgery. Paediatr Anaesth 1999;
10 Kain ZN, Caldwell-Andrews AA, Krivutza DM et al. Interac-
9(3): 243–251.
tive music therapy as a treatment for preoperative anxiety in
children: a randomized controlled trial. Anesth Analg 2004;
98(5): 1260–1266, table of contents. Accepted 23 September 2009