A Drug Study on

REBAMIPIDE

In partial Fulfillment of

Requirements in NCM 218 – RLE

PRIMARY NURSING ROTATION

Submitted to:

CELINA ANGELI B. ASENETA, RN

Clinical Instructor

Alfonso, Kaila Mae Mediana

Aligato, Ricah Jane Credo
Practicing Clinical Instructor

Submitted by:

Dizzy D. Bualan

BSN 4G ─ GROUP 1

September 23, 2022

GENERIC NAME Rebamipide
BRAND NAME Mucosta
CLASSIFICATION Antacids, Antireflux Agents & Antiulcerants
ORDERED DOSE AND 100 mg tablet TID
FREQUENCY
Route: NGT feeding
SUGGESTED DOSE Usual Dose: 1 tab orally 3 times daily (in the morning, in
the evening and before bedtime).
(BY MANUFACTURER)

MODE OF ACTION Rebamipide helps in replacement of lost tissue by increasing

the expression of epidermal growth factor (EGF) and EGF
receptors. These EGF causes angiogenesis, increased
production of granulation tissue and epithelization of ulcer
healing.
INDICATION Treatment of gastric mucosal lesions (erosions, bleeding,
redness and edema) in the following conditions: Acute
gastritis and acute exacerbation of chronic gastritis. Gastric
ulcers.
CONTRAINDICATIONS Patients with a history of hypersensitivity to any ingredient of
this drug.

SIDE EFFECTS • Skin: Rash, pruritus, drug-eruption-like eczema

• Gastrointestinal: Constipation, bloating, diarrhea,
nausea, vomiting, stomach upset, heartburn,
abdominal pain, belching, taste abnormality
• Others: Cold sweat, difficulty breathing
ADVERSE REACTION • Significant: Dizziness, drowsiness,
thrombocytopenia, leucopenia, shock, jaundice.
Rarely, liver dysfunction.
 • Investigations: Increased AST, ALT, alkaline
phosphatase, or BUN levels.
AVAILABLE FORMS Tablet form
DRUG INTERACTION No drug interactions between rebamipide and other drugs
are reported.
NURSING 1. Rebamipide may be taken with or without food.
RESPONSIBILITIES 2. Rebamipide should be taken orally in three divided
doses. In the morning, evening, and before bedtime.
3. Check the BP after giving the medication
4. Monitor for any adverse reaction
5.

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