Drug/Classification Dose/Route/Frequency
Amino Acid
Cefuroxime
Pharmacologic: Second
generation cephalosporin.
Therapeutic: Antibiotic
Ibuprofen
Pharmacologic: NSAID.
Therapeutic: Antirheumatic,
analgesic, antipyretic, anti
dysmenorrheal, vascular
headache suppressant
Mechanism of Action
750 mgl, PO, BID (8am . Bloating or swelling of the face, arms,
– 6pm)
500 mgl, PO, BID (8am Inhibits cell -wall synthesis,
– 6pm) promoting osmotic instability,
usually bactericidal
500 mgl, PO, BID (8am Inhibits prostaglandin synthesis.
– 6pm) Therapeutic Effect: Produces
analgesic, anti-inflammatory
effects; decreases fever
Common Side Effect
hands, lower legs or feet, blue lips and
fingernails, blurred vision, chest pain,
confusion, cough, drowsiness, dry
mouth, fever, dry skin,
Frequent: Discomfort with IM
administration, oral candidiasis (thrush),
mild diarrhea, mild abdominal cramping,
vaginal candidiasis.
Occasional: Nausea, serum sickness–
like reaction (fever, joint pain; celecoxib
235 Canadian trade name Non-
Crushable Drug High Alert drug C
usually occurs after second course of
therapy and resolves after drug is
discontinued).
Rare: Allergic reaction (rash, pruritus,
urticaria), thrombophlebitis (pain,
redness, swelling at injection site).
Occasional (9%–3%): Nausea,
vomiting, dyspepsia, dizziness, rash.
Rare (less than 3%): Diarrhea or
constipation, flatulence, abdominal
cramps or pain, pruritus, increased B/P.
Nursing Responsibilities
Obtain CBC, renal function tests.
Question for history of allergies,
particularly cephalosporins,
penicillins. Monitor for signs of
hypersensitivity reaction during
first dose. Monitor daily pattern
of bowel activity, stool
consistency. Monitor for nausea,
vomiting. Evaluate hydration
status. Evaluate for inflammation
at IV injection site. Assess skin
for doxazosin 395 Canadian
trade name Non-Crushable Drug
High Alert drug D rash. Check
mental status; be alert to
tremors, possible seizures.
Assess sleep pattern for
evidence of insomnia.
Assess onset, type, location,
duration of pain, inflammation.
Inspect appearance of affected
joints for immobility, deformities,
skin condition. Assess
temperature. Monitor for
evidence of nausea, dyspepsia.
Monitor CBC, renal function,
LFT. Assess skin for rash.
Observe for bleeding, bruising,
occult blood loss. Evaluate for
therapeutic response: relief of
pain, stiffness, swelling;
increased joint mobility; reduced

Multi Vitamins + Ferrous
Sulfate
Therapeutic class: Iron
supplements
Pharmacologic class:
Hematinics
Vitamin A,C,E + Zinc
Chlornexidine Di gluconate
Pharmacologic: Benzene and
substituted derivatives
Therapeutic: anti-infective and
antiseptic preparations
joint tenderness; improved grip
strength. Monitor for fever.
1 tab, PO, qd (8am) Essential component in formation Frequent: Constipation, diarrhea, Assess nutritional status, dietary
of Hgb, myoglobin, enzymes. or upset stomach history. To prevent mucous
Promotes effective erythropoiesis membrane and teeth staining
and transport, utilization of oxygen. Occasional: stool turns black with liquid preparation, use
Therapeutic Effect: Prevents iron dropper or straw and allow
deficiency. Rare:  allergic reaction, solution to drop on back of
including: rash, itching/swelling tongue. Monitor serum iron, total
(especially of the face/tongue/throat), iron-binding capacity, reticulocyte
severe dizziness, trouble breathing. count, Hgb, ferritin. Monitor daily
pattern of bowel activity, stool
consistency. Assess for clinical
improvement, record relief of iron
deficiency symptoms (fatigue,
irritability, pallor, paresthesia of
extremities, headache).
1 tab, PO, qd (8am)
1 palm full (5ml), daily, Chlorhexidine’s broad-spectrum allergic reaction: hives, severe skin
vaginal/perineal wash antimicrobial effects are due to its rash, severe dizziness, severe burning,
ability to disrupt microbial cell itching, or redness; blistering or peeling;
membranes. The positively swelling or severe skin rash; or any
charged chlorhexidine molecule other severe irritation of treated skin.
reacts with negatively charged
phosphate groups on microbial cell
surfaces - this reaction both
destroys the integrity of the cell,
allowing leakage of intracellular
material, and allows chlorhexidine
to enter the cell, causing
precipitation of cytoplasmic
components and ultimately cell
death. The specific means of cell
death is dependent on the
concentration of chlorhexidine -
lower concentrations are
bacteriostatic and result in leakage
of intracellular substances such as
potassium and phosphorous,
whereas higher concentrations are
 bactericidal and cause cytoplasmic
precipitation.
Reference:
 https://go.drugbank.com/drugs/DB00878
 https://www.webmd.com/drugs/2/drug-169541/multivitamin-ferrous-sulfate-oral/details
 https://www.drugs.com/mtm/chlorhexidine-topical.html
 Drugs.com
 Nursing Hand Drug book, 2016. By