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Tuberculous lymphadenitis is the commonest form of commonly known as an IGRA, and is a modern

extrapulmonary tuberculosis. Cervical lymph nodes are alternative to the tuberculin skin test (TST, PPD or
the most common lymph nodes affected by this disease Mantoux).
—classically termed as “scrofula”. Scrofula is a
tuberculosis infection of the lymph nodes in the neck. Histoplasmosis is Immunodiffusion test is used to
detect antibodies to Histoplasma capsulatum. The
Scrofula, the Latin word for brood sow, it is the term antigen used is a culture filtrate. Histoplasma can cause
applied to tuberculosis (TB) of the neck. acute or chronic lung disease and progressive
disseminated histoplasmosis affecting a number of
This condition happens when you only have high blood organs. It can be fatal if untreated.
pressure* during pregnancy and do not have protein
in your urine or other heart or kidney problems.  Blastomycosis The blastomyces antibody
immunodiffusion test is used for the in vitro
Hypertension induces systemic inflammation, but its determination of precipitating antibodies to
impact on the outcome of infectious diseases like Blastomyces dermatitidis.It presents as a pulmonary
tuberculosis (TB) is unknown. infection after the inhalation of spores, and it may be
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8563 either asymptomatic or have severe life-threatening
167/) complications like acute respiratory distress syndrome.

A neck mass is an abnormal lump in the neck. Neck AFB tests are usually ordered for people with symptoms
lumps or masses can be any size—large enough to see of active TB. The tests look for the presence of AFB
and feel, or they can be very small. bacteria in your sputum. Sputum is a thick mucus that
is coughed up from the lungs. It is different from spit or
Lymphadenopathy is the term for swollen glands or saliva.
swelling of the lymph nodes. The lymph glands are part
of the immune system and help fight infections and Acid-fast bacillus (AFB) is a type of bacteria that causes
other disease. They are enlarged when the body is tuberculosis and certain other infections.
fighting infection or other diseases.
Anorexia nervosa, also called anorexia, is a potentially
A cyst is an abnormal pocket of fluid, like a blister, that life-threatening eating disorder that is characterized by
can form in many different areas of the body including self-starvation and excessive weight loss.
the skin, genitals and internal organs. A cyst can vary in
size from a tiny sac right up to a heavy bag containing Dysphagia is the medical term for swallowing
litres of fluid. difficulties.

Both bacterial and viral infections can cause neck Odynophagia is a disorder in which swallowing feels
masses. Occasionally, the lymph node becomes painful. A person may feel pain in the throat, mouth, or
necrotic, and an abscess forms. food pipe (esophagus) when swallowing food, liquid, or
saliva.
Activated cytolytic T lymphocytes kill M. tuberculosis-
infected macrophages, leading to destruction of CECT (contrast-enhanced computed tomography) is an
surrounding tissue.  imaging diagnostic method that helps your doctor to
take a clearer and closer view of your internal organs
lung (pulmonary) nodule is an abnormal growth that and soft tissues in the body. 
forms in a lung.
In CT-scan, hypoattenuating describes areas on an x-ray
Right Lung Opacity. These gray areas indicate increased or CT scan that show up as whiter or brighter than
density inside the lungs. normal.

The meaning of INCARCERATION is confinement in a jail Abscesses are seen on CT as cavitary lesions with or
or prison : the act of imprisoning someone or the state without a fluid level. 
of being imprisoned.
An abscess is a painful collection of pus, usually caused
QuantiFERON-TB Gold (QFT) is a simple blood test by a bacterial infection.
that aids in the detection of Mycobacterium
tuberculosis, the bacteria which causes tuberculosis Fine needle biopsy helps to distinguish inflammatory,
(TB). QFT is an interferon-gamma (IFN-γ) release assay, reactive, or cystic lesions from neoplasms as well as
benign neoplastic lesions from malignant ones. In hypertension, it is thought that initial tissue damage by
elevated blood pressure releases cellular debris that
signals a localized immune response. In genetically
AFB tests are usually ordered for people with symptoms predisposed individuals, this initial immune priming may
of active TB. The tests look for the presence of AFB lead to a more potent immune response and additional
bacteria in your sputum. Sputum is a thick mucus that organ damage and
is coughed up from the lungs. It is different from spit or hypertension……………………………………………………
……………………………………Disseminated tuberculosis
saliva. is a mycobacterial infection in which mycobacteria have
spread from the lungs to other parts of the body through
Acid-fast bacillus (AFB) is a type of bacteria that causes the blood or lymph system.
tuberculosis and certain other infections.
Reactivation of latent TB can start in the lymph nodes
resulting in dissemination of the bacteria to the lungs and
Granulomas represent a pathological hallmark of TB. other organs.
They are comprised of impressive arrangement of
immune cells that serve to contain the invading
pathogen. However, granulomas can also undergo
changes, developing caseums and cavities that facilitate
bacterial spread and disease progression. 

Hx (abbreviation in medicine) - history

Supple - moving easily; flexible

Of the approved drugs, isoniazid (INH), rifampin (RIF),


ethambutol (EMB), and pyrazinamide (PZA) are
considered first-line anti-TB drugs and form the core of
standard treatment regimens
R- Ifampin Rifampin is in a class of medications
called antimycobacterials. It works by killing the
bacteria that cause infection. Antibiotics such as
rifampin will not work for colds, flu, or other viral
infections.

I- Soniazid Isoniazid is used to treat tuberculosis


(TB) or prevent its return (reactivation). It may
be given alone, or in combination with other
medicines, to treat TB or to prevent its return
(reactivation).

P- Pyrazinamide Pyrazinamide is used with other


medications to treat tuberculosis (TB). It is an
antibiotic and works by stopping the growth of
bacteria.

E- Thambutol Ethambutol is used to treat tuberculosis


(TB). It is used with other medicines for TB.

Shorter regimens help patients complete treatment


faster. 

TB is known to be transmitted by airborne infectious


aerosol in the 1–5 μm range which are small enough to
remain airborne and disperse on air
currents. …………………………………………………………
………………………………..primary tb
infection………………………………After an initial infection,
the bacteria that causes TB often becomes dormant in the
body. But if left untreated, it can become active and
infectious………………………………………………………
…………………………………………………………………..

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