CHEM 311 (211) First Major Exam 2 HOURS

Monday October 11, 2021

STUDENT NAME: ..................................................................................

STUDENT ID NUMBER: ........................................................................

Test Code (00)

(16 Questions)

Read the questions with clarity, and understand the questions before
answering

Instructor Section
Dr. Tarek Kandiel 1
Dr. Asem Alenaizan 2 and 3
Dr. M.A. Morsy 4

Generic equations and physical constants

R = 8.314 J mol-1 K-1 Sequential First-Order Reactions

kB = 1.381×10-23 J K-1

h = 6.626×10-34 J s

1st order reaction:

2nd order reaction:

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Arrhenius equation Parallel Reactions

Eyring equation

Thermodynamic parameters &

Arrhenius activation Energy

Reversible Reactions and Equilibrium

Michaelis–Menten rate law.

Lineweaver–Burk equation

Michaelis–Menten rate law (in

presence of inhibitor).

Langmuir isotherm equation.

Generalized Lindemann rate law

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1. The half-life time for the following elementary reaction: 2A  B is 90 s at 25 oC.
When will the concentration of A drop to 20 % of its initial concentration at the same
temperature?
A) 360 s
B) s
C) 0.044 s
D) 18 s
E) 180 s

2. Consider the following sequential first-order reaction: A  kA

 I kI
 P where the
rate of intermediate production is much faster than its rate of decay. Assuming that a
third of the reactant is converted to the product in 5 seconds, estimate the rate constant
for the intermediate decay (kI).
A) 0.081 s-1
B) 0.023 s-1
C) 0.151 s-1
D) 0.261 s-1
E) 0.001 s-1

3. Reactant A is converted to products B and C with rate constants given by: kB = 1.5 s-1
and kC = 0.5 s-1. Estimate the half-life period of the consumption of reactant A.
A) 0.347 s
B) 1.38 s
C) 0.462 s
D) 2.885 s
E) 3.690 s

4. Which of the following statement(s) make a reaction mechanism considered correct?

(I) The sum of the proposed elementary reaction should represents the overall reaction.
(II) The sum of the stoichiometric coefficients of reactants in the overall reaction is
equal the reaction order.
(III) The sum of orders in the rate equation derived based on a valid mechanism is the
reaction order.
A) I and III
B) I only
C) II only
D) II and III
E) I, II, and III

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5. The proposed mechanism of para-hydrogen conversion to ortho-hydrogen
( para  H 2 ( g )   ortho  H 2 ( g ) )
keff

is given by:

Express keff in terms of the rate constants of the individual steps.

A) k
keff  k2 ( 1 )1/ 2
k1
B) k
keff  k2 ( 1 )1/ 2
k1
C) keff  k1k2 / KC
D) 1
keff  k2 ( )1/ 2
KC
E) k
keff  KC ( 1 )1/ 2
k1

6. Cyclohexane interconverts between a “chair” and a “boat” structure. The activation

thermodynamic parameters for the interconversion from the chair to the boat form are
Δ # H o =31.38 kJ.mol-1 and Δ #So =16.74 J.K -1 . Calculate the rate constant for this
reaction at 325 K.
A)   108 s-1
B)   1013 s-1
C)   10-5 s-1
D)   10-7 s-1
E)   103 s-1

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7. The proposed mechanism of the reaction:
2 H 2 ( g )  2 NO( g )   N 2 ( g )  2 H 2O ( g )
K app

is given by:
H 2 ( g )  2 NO( g )  K1
 N 2O ( g )  H 2O ( g )

H 2 ( g )  N 2O( g ) 
K2
 N 2 ( g )  H 2O ( g )

Assuming the steady-state approximation, what would be the overall order of this
reaction?
A) 3
B) 2
C) 2.5
D) 1
E) 1.5

8. Consider the following mechanism for the thermal decomposition of R2:

R2 k1
 2R
R  R2 
k2
 PB  R
R 
k3
 PA  R
2R  k4
 PA  PB
where R2, PA, PB are stable hydrocarbons and R and R' are radical intermediates. Which
of the following is the correct rate expression for the thermal decomposition reaction of
R2?.
A) d [ R2 ] k
 k1[ R2 ]  k2 ( 1 )1/ 2 [ R2 ]3/ 2
dt k4
B) d [ R2 ] k
 k1[ R2 ]  k2 ( 1 )1/ 2 [ R2 ]3/ 2
dt 2k 4
C) d [ R2 ] k
 k2 ( 1 )1/ 2 [ R2 ]3/ 2
dt k4
D) d [ R2 ] k
 k1[ R2 ]  k2 ( 1 )1/ 2 [ R2 ]
dt k4
E) d [ R2 ] k
 k1  k2 ( 1 )1/ 2 [ R2 ]3/ 2
dt k4

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 9. The adsorption of gas is described by the Langmuir isotherm with K=0.777 kPa-1 at 25
0
C. Calculate the pressure at which the fractional surface coverage is 0.20.
A) 0.32 kPa
B) 0.21 kPa
C) 0.12 kPa
D) 0.50 kPa
E) 0.20 kPa

10. For the Lindemann mechanism of unimolecular reaction: A  fragments

which of the following statements are correct:
(I) Reactants acquire activation energy through bimolecular collision.
(II) The rate of reactants decomposition demonstrates first order behavior at high
reactant concentrations.
(III) The rate of reactants decomposition demonstrates second order behavior at high
reactant concentrations.
A) I and II
B) I only
C) II only
D) III only
E) I and III

11. Which one of the following graphs shows the rate of H2O2 decomposition with respect
to time (assume the reaction is a simple elementary step)?
2 H2O2(l) → 2H2O(l) + O2(g)

Graph (I) Graph(II) Graph(III)

A) Graph(II)
B) Graph(I)
C) Graph(III)
D) Graphs (I) and (II)
E) None of the given graphs represents the process

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12. The given graph represents a first order reaction.

Which of the following mechanisms describes this reaction assuming k1 = 0.1 s-1 and k2
= 0.2 s-1?

(I)

(II)

(III)
A) Mechanism I only
B) Mechanism II only
C) Mechanism III only
D) Mechanisms I and II
E) None of the mechanisms represents the process in the graph

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13. The reaction: CO2  H 2O  HCO3  H  is catalyzed by the carbonic anhydrase
enzyme in the lungs. It follows the Michaelis-Menten mechanism and the plot of initial
rate versus CO2 concentration is given below:

What would be the approximate Km value of this reaction?

A) 2.5 mM
B) 5.0 mM
C) 10.0 mM
D) 12.5 mM
E) 7.5 mM

14. The below figure shows the Arrhenius linear plot for the acid-catalyzed cane sugar
inversion in aqueous solution within the temperature range from 20 to 40 0C.

What would be the standard enthalpy of activation for this inversion process at 25 oC?
A) 49.4 kJ /mol
B) 51.8 kJ /mol
C) 54.3 kJ /mol
D) 45.0 kJ /mol
E) 60.0 kJ /mol

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15. In the reaction:

the diffusion of reactants limits the rate of product formation.

At constant temperature, the rate of product formation will .................................with
increasing the viscosity of the reaction medium
A) linearly decrease
B) exponentially increase
C) linearly increase
D) exponentially decrease
E) remain constant

16. A Kinase-enzyme plays a central role in Alzheimer’s disease and a compound known as
Ro 31-8220 is a competitive inhibitor of kinase-enzyme. The following plot shows the
data for the initial rate of activity of Kinase-enzyme in the presence (200  M) and
absence of Ro 31-8220 inhibitor.

Which one of the following answers represents the values of Km, Rmax, and KI,
respectively?
A) 5.0  M, 5  10-8  M/s, and 50.0  M
B) 5.0  M, 5  10-8  M/s, and 4.0  M
C) 5.0  M, 2.5  10-8  M/s, and 0.25  M
D) 2.5  M, 5  10-8  M/s, and 0.25  M
E) 2.5  M, 5  10-8  M/s, and 4.0  M

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