I .

·:; JZ:.P.I::

PH~S I CIANS Lic e nsur e Exam inat i on _ l O: :) ll a . ill.

Sat ~ir day, Octo ber J O, 2021 00:0 0 a.m.
- --- - - --- - -- - ---- ---- ---- ...----- - -- ---- -· -
--------.....
:::~::::STRY ------ (sET
,
-~--/
I

...___:__..i

JN S RUC TION : . .,,. f,j r e:tch of . the follo wing

Sele c t
qu e ~tio ns. Mar k only
c or r espo ndin g to th e
STRf CTL Y NO ERASURES
I
MUL ji' IPLE CHOICE
the co ~r e ~tf ~~s= =~h ~t em b y shad ing
on e a nswe ~ • · the b?x_ .. ~~
le t t er o f your choi, c e on ~he -
answ er shee t p~o~ id~ u .
ALLOWE D.

\ 1\. Wh ich of the follo wing is NOT s1:-,c ret ed b'"f the ante rior p :i.t•.ii .t a:r~r
(}....\ Oxy tocin · C . ::? ~::.il .:\ c:tin
73. Beta - encl o r phin D . S :.Jma tc,tro pin

Fe t al hemo glob i n has hig he r ox yge n af fin i ty than adu lt

h e m□ glob ~~~
prim arily du e to redu ced a f fini ty to 2,3 -bis pho spho glyc erat
state men t is e. Thl ~
A. part l y true only
B. fals e

Whic h is NOT part of car bohy drat e

mo lecu les?
A. Oxyg e n . C . Eydi 6ge~
B. Carb o n , D',. Oc ta J. ate 1....,.._.,..

', 4) Met abol ic acid osis with out a n abno

r mal anio n gap is cha ract eriz ed by
A. hype =kal emic acid osi~ c. , hype r c ., ,r bon ic acid osis
B. hype rnat rem ic acid os is D _) :,v1Je r c~1lo remi c a _c idos is
(.:::::;" .( -
I

5 ·l ~{he n--k~ tosis is i nduc ed in c1t.h ,

letc:: f:, th.8 £cl.L owin g i~ expe ct~c:
to oc c_,_;1 ·,
,/E~ c:e: PV ----
---- =-- --~ .
~~_, ;r-ir npro vem ent of musc le- t o - l:2.t r at .10
B. impr o veme n t of endu ranc e /
/.
J§Y enha ncem ent of peak per fo r manc e · .x
1J. Incr ease in oxyg en uti li za tior:
"i-</
\ 6 · w11~·ch is. an ESSE N'I'IA L amin o
a.cic: t?
Ii
.A
B.
Vali ne
Glut amic acid
C . Se ri ne
D, A.s parti :::: acid
_,.,.7 ·! In pati ents with poly cyst i c ovar y synd rome
ben efic ial beca use of the redu c tion , · ,, keto geni c -~!; . nc.y ]:,,.;;
@ ~dre r:C? -cor ticot ropi c
B. insu lin ·
(i'
in the b.ornmfle

'tJ)·,:.,
pr::i geste r one
estr ogen
- - - - - - - - - --- -----·
-~. v . __ _
-....-..... ,,./ - ·--..
\ 8. 'fhe follo wing are . esse ntia l :i utr ·i ents
o:E t.:1e bod y~_ :!-)
A, esse ntia l fatt y acid s
C . es sen tial ~:.mino acid s
~ J enzy mes
D, IT,:', l1<d-r Et 1 s
\ 9. : The .i..nf larrn nator y resp onse i s
cha.1 :ac';: -2x i Zf'J::.. by t he follo wing -', 'EXC3
~~'t ·,
;.-.) l o c~l pain or body a c h es . / ~-·
(~, decr :ease d bloo d c.1.r cula t.1. o1,
c. swe lling of affe cted t iss u Rs
D. incr eas,~ d mucu s proc tuc tJ
.<.1n

Con tinu 0 J 6n Pag e

 I

PHY
_
)!C I ANS Lic. en sur e ,
~at ufc tay , Oc tob er 30,
Exa min atio n .
202 1 - 0B : 00 a. ~ - - 10: 0J a.rn . pag e 2
BIOCHEMI STRY
SE'I' A

\ 10. Whi ch of
the foll ow ing i s NOT d_.p

G;.I:\.)
Cel l ulo s e o l ~Q h.a~ ~ ?
- - - C . Gl\· cog en
Ma lt ose _c.l._. ·).
D. Chi tins •
\ u. 1-Jh:jJ:::.h vit i:l.mi n r eq uir es ~
1 - in the die t for its
(_Jt.) Bi 2 syn the sis?
.:a·. C
D. B6
C. B 1

\ 12 . Wh ~ ' is (TRUE I
,.,....----,
-;;ffi~ The ~ 1~ . iof Typ e 1 di ab e tes
n •1'.t~rTc i en cy ca n b me l l ' tus ( DM?
( -:-~;,,_ com e
bin atio n of .s,xo g e nou s _ins ulieff ect ive ly cor rec t~d !;:{~.t h . a
B. It usn a'll y dev elo ps-b y n and s u lf o ny lur ea ? . ;,-.,:. .
the seco nc. to thi r d dec aa x
C. It dev elo ps bec aus e the e of lif e ·
imm une sys ten atta cks 1;_he
ins uli n-s ecr etin g ,,-l:5eta)
D · The re is, a myocara?t."1i·r::'. cel ls of the pan cre as x
s par ing eff ect com pare d to
Typ e 2 DM
13. Hem e, whi c h is
a pre cur so r to hem ogl obi n,
bon e mar row and the is bio syn the siz ed in ~ot h
th~
(!:) live 1~
' B. spl een c . enc .oth eliu m
D . pan cre as
14. Blo od and uri nar y glu
cos e ar S ana lyz ed by usi ng
glu cos e_- ,--,_ _..,......_ _ _ , whi the enz yme
c h cat aly zes . the rea ctio
. pro duc ts ·tha t inc lud e hyd n of glu cos e to
r oge n per oxid e.
A. pol ym era se · ·
B. dis mu tase
cc) hyd rog ena se
· D. ox.: .das e
~ 15. Wh ich tra ce nut
rie nt is be liev ed to be im:
.me:l.:,.f1..QQ..lism alth oug h its exa olv ed in glu cos e and lip id
ct ·mec han i sms o f act .i on 'cf1T
kno wn yet ?
1
1
d7:l·o·s·a·g e-s- al:e ' NO'l '
i A. Cop per
· B. Mo lybd enu m @.1 Chr omi ur.,
D. Macg ane se
16. ' Wh ich of th e foll ow ing
fat - so lub le vita mir .s pla ys the MOST· sig
Irol e in cel l mem bran e pro tec tion ? r.if ica nt
: A. A
C. D
: Qj.K D. E
_.....-17. i in mon osa cc h ari des
, the nu mbe r ~o fcar ~-on s risu
\ ·¥.ilfl 10- 22 ally ran ges
: ~ - 8--1 2 3 -,
I
13- 17
\ 18. :seJ ._en ium is ess ent ial
1 t.o th e a cti vit y of whi ch
Cl\..,.) Glu tat h {on e · per oxi das enz yme ?
:! .,if. Ald ehy de oxi das e e c. Cyt och rom e C oxi das e
· D . _Sup clro xid e dis mu tase
\
\. 19. ;Wh ich of the foll
ow ing vit ami ns pl-:1.ys
~
'ic·~ age n syn the sis? the mos t sig nif ica nt rol e
in
Asc orb ic · aci d
'.
1
~- Ri'b of_ · 1 av in
'
C. Par _to thei :ic aci d
. D. Ni c:.ci n
\ 20. ,Gly cog en, com pos ed
of a bra nch ed c hair .: of glu
cos e res idu es, is

a\
A, a min or (sec ond ary ) f orm
an ene rgy res erv e for ani
-,/'.. sto red in int est ine s a nd
of car boi ydr ate
mal
bon
s
es
D. sol ubl e in wat er

Con tinu ed on ?ag e 3 TQDS Vex 2 . 1.. ')

 ~:iYSI CJ ANS Lice n s u re Examin at :_on
Sdtu rd ay , Octobe r 3 0 , 2021 08 : 00 a . m. - 10:0 0 a . m. Page 3
BIOC HdHSTRY

\ 2 l. I~-~ heir stor age form , fatty

ac i ds are bound t~
SJ:,,.} glyc erol C . adenine
i B. lipase D . gl_~_c_
c se<. -phosp hate
2 2. l'71~_+_c.h is ~~
of the c qmponen~ J ostrnrp. f
,~ /lPro tei-n" concen trati on 7:s lower'---iff-"c'o-:tc:istrum than in regula r
I
mi2..k .
\ B. In s wine, fat conce ntrati on of milk at 48 to 72
houf(
pos ~partum transfo rms to predom inantly low-de nsity
, lipopr ote in choles t e rol.
(tf) In humans , fat concen tration is lower in colostr um than in ><
milk. . ·
I
'
D. Fat concen tration is al~ost absent in colostr um than in
in most specie s.
milk ,X
I
23. S1 gar alc ohols or glycito ls are
us ~d wi~ely in the food indust ry as

l \A. preser vative s

iB. cons i s te ncy thinne r s
.k£) sweete ners
o. aroma enhanc ers
2'1. D~term ination of insulin -like growth factor
1 (IGF-1 ), also called
s9mato medin c, is the most sens itive teet to diagno se acrome galy
. It is
pl'far ily formed in the
~ J . Llver C . : :<:idney
.. :, Pitui tary gland
I I •.•

b1l .weight .
•

25. Tdace elemen ts consis t a round

(Q_"') Hypoth alamus

percen t of tte human body

I . (~..Jo) 4
li. 16
C . 36
D . 26

26. whkch hormon e r egul ates the secreti on of t riiodot hyroni

ne and thyrox ine?
~ - Thyrot ropin-r e leas ing hoimone
I B. Calcito nin .
,,-, ·~ hyr oid s timul at ing hormone
hyrogl obulin ✓- .
~

I \ 27. Th ~ ·revers e proces s of gl yco lys is i s

(&) gluc oneoge nesis
f glyc o genoly sis
· • C. ga lactoly sis
D . glycoge nesis

I 2 8. th~ major macro~ inerals or mac r onutrie nts cornpos e about

pet cent of the human body by weight .
A. 96 · C . 7f,
(!) 86 D . . 66

II \
I
29. which is the LEAST involve d in .
A. Weight .as.u:i::.em
.--'\,-.,..~~- ,,c-T':° G- ratio en:t.s..1...
~ - Height cumfere nce
I
..30 . Th' fre~ f atty acids enter the blood attache
., • d to
Jt. .
eryth rocyte s O albumin
~ . globu lin 't?. glucaqo n
3 1. Wh~t is the signifi cance of t he ~ ~s.0c;;.i.a.±..i,Qn curve (ODC ) ?
A. It shows how the he~og l obi n· saturat ion ,;,:1th oxygen , is
relate d to the partial pressur e of c xyge n in the blood . X'
B . It ~1 7ar ly demons trates that hemoglc bin ha·s an increas
ed
affinit y fo ~ the oxygen molecu le and release s oxygen to tte ,.,,.
tissues rapid ly at lower partia l pressu res. . ~ .
C . It expla~n s t ha~ anemia , in t he abse~ce of other hemato logic
abnorm alit ies, i~ not a c ause o rris~ factor of more severe
cardiov aicu lar d i sea s es or a mar ke r of other pr ocesse s.

Continu ed on Page 4 TQDS Ver 2 . ·1 . 9

 ?H Y..:,ICI AHS L ie::= -. s :: r e Examir:c ~.:..::7 p age 3
• . .. jC : JO a.m .
Sat,-i:i:h , y , Oc t-::2e- - 30 , 2 0 21 - '."": -

BIOGiEMISTRY ---
SET A

• r re t,ound t o
21 . rn ·· -.:. he i r s t:.orE1o e form, r "'t.~y -~c J.;::.:> !de n ine '
(f.,.l g ~y ceroJ - ~ : gl~.J_c _c se- :. -phos ph ate
8. l.tp ase _,,,,---· ,
✓-~ t i; c ,( c.oJ astrnrn'?
22. lvJ~,4<_c.17 is (.Tl<,U_,El of the CQJ~po mrn ~ ,.-'-j_41..3cbro'st r um than i n r egu l a r
tJ:/ lP ro t.e'i-n c o nc e ntra t ion is O - .
, mi ~k . . f ' lk at 48 to 72 hou r p
, B. In swine, f at c o n ce ntr a t i o ~ ~ ~ J. ~tly l ow- density ~
po s ~ p artum t ransf oims t o ~rec o minan
l ipoprotein cho,les terol . , , , in colostrum than in '> (
([§:) In humans, fat concentration i s lov.er
i
10. mil k .
Fat concentration is al mo s t ab sent in . -colostrum tl1an in milk. )<.:
in mo s t species.
23 . sJ oa~ alc o h o ls or glycitols ar e u s~d wi~ely in the food industry as
I" . .
!A, prese~vat i ves -~ sweeteners
:B, consistency thinner s o . aroma enhancers
I. 24. D~termina tio n of insulin -l ike growt h factor 1 (IGF-1), also called
s 9ma to~edin c, ii the mos t se n sit i ve test to diagnose acromegaly. It is
p ~i~arily formed in the
dt9~
LJ.ver C. ~idney
~ } Pitu i ta ry gland Q;i) Hypothalamus
2 5. TJ ace elements consist around percent of tte human body
byl_ ._weight .
. (j\__.J 4 C . 36
'B . 16 D . . 26
26. Wh ~ ch hormone regulates th e secre t ion of triiodothyroni ne and thyroxine?
~- Thyrotropin-re leasin g hormo n e
B. Calcitonin .
,,.. ~. -~ Thyroid stimulating h o rmo n e
hyroglobulin ✓· .
-:;;;:,,,

~rh~ ·reverse process of gl yco l ys i s is

a;) gluconeogenes is · . C. galactolysis
f glycogenolysis D . glycogenesis

28, 1hi major macr6~inerals or macronutriente cornpose about

petcent of the human body by weight .
A. 96 · C. 7 ~
(!) 86 . D • . 66
I
\ 29. Wh.:\.ch is tlrn LEAST involved in . ~~~~:=-r? ~.......as.ur.eme.n:t.s.1..
1·
Weight
~- Height
ratio
cumference

.,,...30 • Th~ fre~ fatty acids enter the blood attached to

~- erythrocytes ..{) albumin
B. globulin
I
tr. gluca~on
i
31. Whqt is the significance of the oxygen ~~so.cia:t..i9n curve (ODC)?
]¼.. It shows how the hemoglobin·--s aturation with oxygen, i s •><•
related to the partial pressure of cxygen in the blood. '
B. It clearly demonstrates that hemoglcbin ha·s an increased
affinity for the oxygen molecule and releases oxy~en to t~e
tissues rapidly at lower partial ~reasuies. . ·. .
q. It explains that anemia, in the absence of other hematologic
~bnorma l i t ies, is not a c au s e or rie~ factor of more severe
car~ ioVa $CUlar diseas es o r a ma rke r of other processes.

Continued on P age 4 TQDS VE:r 2 . 1. 9

 I
PH YSIC I AN S Lic en s ur e Exami nati o~
Satur da ~ , Octo b e r 30 , 2021 - · 0 8 : 0 0 a .rn . - 18 : 00 a,m.
! Page 4
BI OC HEHk STRY
. . SET A
~ > It s how s that when a n~ mia . de v e~ op~ over a long period of
- : · time , th e oxyhem og lobi n d1 ss oc 1 a t10:~! curve i s shif ted to the
' left .
\ 3"2. Xa ~ thin~ i s conve rted to ur ic acid by xa ~t~i ne
6v ox id a.s e C . phosp: ,a,tase
B. nitrog enase D. carbo:: -.:ase
3 .:,-, . Wh ~ch is ~ ) an infl'!m mato ry re sponse assoc iated
with
pr ostag la n dins?
(;fiNumb ing of pain rece ptor s
a··. Attra ct i ng phago cytes ,.,/
C. Local v asodi lation
i). Attra cting neutro ph.i. l es .p'
\ 3 4. Wh~ch tra ce nutrie nt i s requir ed fo r the
functi oning of xanth ine
o~x
·· lase?
~.) Coppe r c . Chromium
-. Manga nese D. Molybd enum
I

_35. In : women , the glyca ted hemog lobin (

Ale) ref lec::s the weigh ted aver:tg e oJ:
bl{,od gluco se levels duri ng the life cycle .redblo
od cells, which i3
arQun d ~ - - - - - - - - .days. · ·
/4) 106 c. 90
e.
I
130 i!:i..7i 1 1s
~

SITUA Ti t NAL
l·
Situa tibn 1 Esse ntial ly all ·pro t eins that are known to fold kineti
twb-s tate manne r have the i r N- and C-term inal second cally in a
ary
stfuc tural eleme nts in co nt ac t , and the term.:: nal eleme
nts often
dofk as part of th e exp~r iment ally measu rable initia l foldin
st p. . g
To which termi nal do the follow ing refer. to: I. N-term
inal, II.
C- -t ermin al?
\L 36. If-k1-S
j the end of an amino
' a ci'd c1ain
l . ( protei.n or po 1 ypep t"d)
1 e
C,,_A.i II only . C. I, II
ij. Neith er I or II D. I only
\~ 37. It lcons ists of a free -COOH struc ture.
A. Neith e r I or II . c. I, II
B. I B J- II
38. Th~s is the termin us that conta ins t arget ing signa ls.
~ Neith er I or II c. I ., I I .
~: II I
-~
3 9. Th:ts termi nus conta ins reten tion siana ls £or orotei n sortin g.
I, II - - -···· - · C. I

(5)
,fr.· Neith er I 6r II D. II
w1Jc11 is the termi nal end ( s) of prote ins that can be modif~
-~, 4, 0. ,.,olt-tra ns lation e~
ally, most commo nly bv the ac.di tion of a. lip:.d ancl~or
~0 -
~hJt allow s the prote in to be i'nsert e-d J·.nto a membr ane witho ut having a
tr~nsm embr~ ne domai n?
A. Neith er I or II ~ I , II
~ II
~ I
Contin ue d on P~~e TQDS Ver 2.1 . 9
I 5
I
I
I
I
 i

PI-JYS I 'C IAN S Li ce n su re

Exa m :~ n at io n
Sa tu r l ay , Oc t ob er 30
, 2 0 21 08: 0 0 a.m . - 10 :)0 a . rn.
§_IO CH • MI ST RY Pag e ~i

Sit' ..ta .l~i on . 2 - Th e A SET

Co mp lem en t S y~ tcm (CS
1.1mnun :Lty . Th ere are ) µla ys an im poJ :ta nt
thr ee d1. f f ere nt typ es sup po r-ti
1II ! Al ter na tiv e, and of cs: I. Cl as sic al, ve
II I. Le cti n . Wh ich of ro le .i. n
~ cll ow ing mo st re lat the se typ es are the
e d to or a s so cia ted
wi~ h the fol low ing ?
\
1
l l . f-vh ic b✓ sta rts
wh en an t ibo dy bi n ds
A. No ne to -ba cte ria ?
I @ :c C. II
D. III
\ 4 2 .· ~~~~hsta rts "sp on tan eo us -_y
"?
-~ I
U II C. No ne
0. III
\
l3· rhich
4
J..\. I
sta rts w.i .th, bin din g
l: o ina
~ os e on ba cte ria ?
.
B. . III
I I
. . I, :I I & I II
\ 44 . hic h req uir es an tig en
-an t i bod y ·co mp lex es for
A. I II ac tiv ati on ?
C. I, II & III
B. II
I®
\_ 43 . Ph
\ ich cle av es C3 -co nv ert a·se
A. III and ac tiv ate s com pon

l
ent C3 com ple me nt.?
C. II
B. I .,-----------~
Si tua io::1 II & III
3 - . J.z hei me r' s di sea se .
~h at us ua l ly pre sen is a ch ron ic neµ rod ege
s J.. ner ati ve dii ;ea se
~ir ne. It is the c~ use n sJ.d iou sly bu t pro gre ssi ve ly wo rse ns ov er
\ 4 6.
1
l
hit ::h is the
A. Ta u pr ote ins
B. Pla qu ~s in bra in
G
o~ 60- 70 pe rce nt of aa
ass oc ia ted wj_):..q .A;:)?
(£ ) Tro p8 nin s •
dem ent ia ca ses .

I
ce l ls D. run yl~ ids .
1
4 7 ; Ai t I1 e or y J.· n AD i·
5 tl1 e lac k or red uce d sv nth esi
I
_ s of the neu rot ran srn itte
I j~
A. sy na pti n ~a ce t:{ lch ol in e
B. me lcl ton in b':_.... meth-:t lne 1.1 ron in
W~ ich syn dro me un ive
rsa lly ex hib its the ea rli es t sym pto ms
4~ ¥e ars of age ? of AD by
(_A.:. ! Do w n's C. Sjo g.:: -en
1 13. Ke rni g' s -~ Mc Cal lom
.
LI !l . w~ at ge ne tic -~ ele tio ~ ~u tat ·
rep or_ e d as an As ian ped i~r ee,
ion ~f AD?~~ t
a 1d kno wn :Eo r its fam
, A, Os aka mu tat lon ili al oc cu n:e nc e . .· . en
!B. Ta ko tsu bo mu tat ion c.< Har .a}: J.r 7 dem tia ..
@ Nag a} alu dem ent ia
\ wt ich pr ote in is hy po the
SO · n~ lll; Of ibr iJ. lat siz ed ·to· als o c~ use A~
ory tan gle s ins ide ~~ hea
~e ;l.l bo
bl
for mi ng
IA Mu die s
1
, B ..
•
Sig ma
c. T .
1
Pln
• •

.. j _ Tl1 e sk in is pa rti cu
S l. t..- u at- ·o 11 4 lar ly se ns iti ve to cha in boc iy tem po c;1t 1.1.c 1~
1
a1 d ass 1." '
lJ
fee o)a c ,
·
Jc
c,t in
thu s
pro vid ing us efu l thr ou
. , . gh t .h e 1,ro
t •
ma :Ln ta1 .n1 .no cl co nst an co re tem pec atu re.
- ·
nge s
ceS Ei of neg,:1 tiv
· "
e

. _; tem
,•5 1.
, pe rat ure
I1 skl . 11 t re the bod yis can
t,p er a u , ;
. , • con :7e c~ -on
.•·~ ;1 .r.e ic1 iat1 on
·
hig he r tha n tha t o,/: the sur r~u nd ing air
los e he at b y ~ - . -
. C. eva.pc-: rat 1on - - - - -
D. tra nsf t1s ion

\ 'l'QDS Ve}: 2 . l. 9
Co nU. nue :d on Pag e 6
 y ~,l C I:, N s L i C C r: .s l '. r '= E ~'. Cl mi r. a t i. =:7
. J ,·]

Sa t ur d a j , Octo ber 30 ,
2021 03 : JJ a. ~ . - 10 : 0 0 a . m. Page 6
BI OC:[·JE Ml STRY - SET A
52 . ~- air te mper a t ur e of the su r rou n din g s i E gr eater than that o f the sk
1 i n,
the body regu lat es temp e r a tu r e S)'---- .
A. radi a t ion c.__s, c o nduc t i on
D . confe ction o . ev apo ::ati on
1·
ou t ing inte n se exe~ cise, the mai n me chani sm for therm oregu latio n is

{\ : evap orat i on @ c onve ction

B. radia ti on
I
"'if. c ondu ct i on
54 . Hu~ idity af f e c ts therm o r eg ul a tio n by
hl),
limi t i ng conv ect~o n
B . conse rv ing body hea ~
1· limit ing swea t evapo ra t ion·
m. enhan c in g cond uctio n

.5 5 . Tl11<f\ p h ys1.o
·. l '
ogica 1 contr ol. of the . bo d y's c::ire t.emp
·
eratu re, servi ng as th e
9.€11:t-X ' s therm ostat , is pri ma r .i l y l o cated in th.e
~ thala mus c. h ippoc ampu s
~ - medu l la ob l o ngata D. h ypoth 3lamu s
't ua t. ion
.S 1·: · 1 5 - A l z h e i' mer's disea
' s e (AD) i s a prog ressi.ve neuro dege nerat ive
di ~ ease, grad ua ll y worse n ing o vr'"r ti me. '!'houg
h its
pa ~h ophy sio l o gy i s · not t ha t i h or o ughl y unde
rstoo d yet, sever ~l
metj h anism s are con s i de r ed , amon g whi ch are:
I. Chol inerg ic
h y ~oth esis , and II. Amylo id h yp o thesi s. Indic
ate which of these
hy~o these s t he follo wi ng a r~ relat ed to or assoc
iated with.
Th ~ olde st hyp o thes is (es ) O'.l whi c h mo st c~rre ~tly avail able drugs for AD
a;/~ based ?
~_81~ II C . Both
B]. Neith e r
;
I (Sr
5 7 . Res}, ced neu rotra nsmi t ter s ynt he sj_ s?

c_p
f-;f__, TI
I
C, Both
D , Neith er
58. Ex~~ acell ula r depo sits~
Q.\ I, I I c. Neith e~
. ~ Both D. I
,~59. sup~ ort for this hypo thesi s is the locat
ion of gene for precu rsor
pro·l: ein?
.A f Neith er E)so th
B II J!12 I
1
-··60. Linlt ed with Down syndro m,3 (Tris omy 21)?
.C~ Both C. I
13 ,I Neith er D. II
I
Situa tioi1 6 - InfJ.a mm,:t tion is one of t:he first
respo nses of the immune E-Y5t em
to ~ nfec tion or irrit atio n.
61. w1~-..d h i ~ ) a b o u t inflam matio n'?
✓- • \ It faci litat es sprea d of infec t i on
y•,
It is tr .~gge re db Y ceJ.· ..·1ll.1 ar in
' Jury
' /
--:5)\ 1
rt is stimu lated . by c::~:;,m :u;:al fac1:- ors
-~- rt prom otes heali ng or d a maged tissue
' 1· 11i'·t1.' ..... d
✓
,,,,,,----
G2 . Inflia mrn~t ion :Ls · '·"'t
' "' J:, \:
J
:>11 ,1
.;, J
rJ f 1· ·11 ""' ·f ollow 1··,1g cells _,~;XCE PT)
- '°' ~
'
I

- - ~ h i s t iocy t. es C. ma st ce:.l s ./
/8J D. dend -::-it.:.c calls "'
--- c, c i n eu.-- ce.lls

9
Con ti nupd on Pa ge 7
 - - •- -- u \_\ .!_ c:; J.:,J .i'. ,L~ J tl__.!.. - ;. . I ' - • '~ '"-" • •
S cd:nJj d a y, Oc:t.o ber. 3G, 2 02i :-- 08: CG m.
1.. • • - :;.J; QQ a . m . Page ,
I
B IOC H_~MIS TRY
SE'l' A
----
\ 63. \ 1:·ou.n _ l.n th e hepa tic~ ~ ~"i.!ls, which -cell s initi ate the proce ss o t
; inflam ma tio n? -- --
A. Sinu soid al ..@) Kupf fe r
13. Cowp er D": Inte rstit ial
~ ,.1 . Cells th at ini tiate inflam ma tion ha ve surfa ce or
calle d intra cellu lar ~ecep tor s
1-••)~ rece ptors .
~{#/). patte rn reco gniti on C. forei gn body
(_~) patho gen pa.tte rn _ D . ce : lular spike
65. Whic h of the follo wing
,,,-- · i n :Elam matio n7
i 0·~~~~ chem ical f acto:i ; produ ced durin g
A. leuko tr ienes ~ c. antih is~am ine 7
~ (!) s~ro tonin D. brad ykin in
• I '
SJ.tucjtion 7 - The oxyg en-he mogl obin di ssoc iatio n curve
, also cr.1.lle c.
:the oxyh emog lobin disso ciati on curve
1
oxyge n disso
curv e (OD C), is an impo r tant tool for unde rstan ding ciati on
c,r
1
carr ies and relea ses oxyg en. how our blood

\_ 66. !The ODC relat es the oxyge n satu

ratio n witt the of
1oxy_9_en.
! ~p blood solu bilit y c. part ial press ure
• (!) util i~at i on · ratio D. che:n iosmo sis
67. Whic h facto r is ~ i n v o l ve d in the
ODC?
. ~, Diss oluti on rate of oxyge n .,.,,...,,.
(~...; Rate at whic h hemog lob in relea ses oxyge n
t Hemo glob i n affi nity ·for oxyge n
. (5 Rate at whic h hemo globi n acqu ires oxyge n
I

~ 68. rrhe ODC is BEST d9s cr ibed a s a @: · . plot.

1
A. line ar · C: c1;1r 1i~in ear
1
B. jagge d • D. sigm oid

\ 69. iin the stand ard ODC, a leftw ard shi~ t indic ates 01,yge n
iaf finit y.
· J.\. lowe r @ higl1 er
B. varia ble JS. minim al_l y satur ated
', 70. bn the othe r hand , a right ward shif t i~ tha ODC indic
ates
· ·1 oxyg~ n affin ity.
A. varia ~bl e ) lowe r
B. maxi mally satur ated ~ highe r
Situ alion 8 - ~orp hyrin s are a gro~p of he~e
rocyt ic rnacr ocycl e organ ic
fomp m.md s, which . serve s as a co_f actor of '!:he prote
.i.n hemo globi n·
~orp hyiin s are comp osed of pyrro le aubu nits.
i A ·. 8 --c-. -4 ·
D. ·2
I (!} G
I ,
..,..... 7 2. Its subu nits are inter conn ect.e d at their alpha -car b 01,• atom. s via
I . bridg es.
_A___m_e__,..t,...h-:i-n_e_ _
~ . lysin e
B. se.rin e ~ 0 ala:.·_ in.e
[ ie po.rp hy~ in
· r i1g struc ture is domin ar.:.tl y
l
A. acyc lical /.::~ asynr netric
I
1
H . nonl inea r ' ro aron atic
\.' r-2-:r 2 . 1 .. 9
Cont inued on Page 8
 PHYS .llC IANS L ic e nsu re Exami nation
Sa t u~"d ay, Oc t ob er 3 0 , 2 0 L
~l 08 : C0 a.m . - 10 :00 a.m. Pag e 8

BI OC BEMISTRY SET A

74. ,HemE ,1re por phyrin s con t ai ning

A. iro n c . phc,s phc.te
.
~
\b' g 1 o J::>U l i n D. tyr os1.r:e
7 5. :Th e commi tted step for porph yrin biosy nthe:s is is
the forma tion
'4·
lo :E

~)
6-pyr uvi c acid
6-ami nolev ulinic acid · ·
~ O-glu tarnat e-1-se miald ehyde
I D. 6-g lu tamic acid
situ ~t ion 9 - Oncog enesis (OG) is the proce ss throug
h which health y cells
becom e t r ansfor med into cance r cells .

/ i •
.
76. !The foll owing chang es anc1 . p roc esses are involv ed in OG ~ -----
1 ?() epimu tat ions C. genet ic rr:utat ion
~ oncog ene activ ation D. cellu lar hyper trophy
\ 77 . Progra mmab le cell death , which may also be assoc iated
with OG is termed
A. acyto sis c. ka~yo cytic .death
® apor,1to sis D, apa-:h y
78. &~ch vi ru ~ ~s oncog enic ?
1
V.
Oncov. 1.r 1. n ae . c: . Can:::er virus 201.9
· B. Viruc ~ncer ae D. Hepa titis A-· ~

\ 7 9. ~enet ic t rans locati on occ u rs when two separ ate·

chrom osoina
becom e abncrm ally fused, often at a chara cteris tic locati l region s
~opul ar examp le of this is the on, and a
A. Chrom osomes X and Y CB. Philad elphia chrom osome
B. Chrom osomes 5 and 15 D. Calif ornia chromo some
\ 80. f\b,m[e ge netic transl ocatio n i s stron gl ~' a s sociat ~d with
; Ct) chro nic rnyelo genou s leul<:emia what diE:ea se '?
1
chron ic lyrnph ocytic leukem ia
~:

C. Down 's syndro me ;<

D. Imbec i lity disord ers
Situa t i on 10 - A thermo dynam ic proce ss i s define d as the
ene rget ic ev,lut ion of
~ therm odyna mic system proce eding from ~n initia
l siate · to a · -
f j_nal state . Sever al commo nly studie d ·:herno dynam ic proce sses
includ e: I. Isoch ronic , II.
of these pr~-s --a--. re the f oIsentr o p ic 1 II:. Stead y-stat e. Which
l lowing relate d t o or assoc iated
ti th?
,O·l. tt.can be descr ibed by proce ss quant ities?
1(,_i") 11 · C. III
I B. I · D. I, :I & III
,..... 82.
I . .
' 1I t .A.invo~
None
ves all param eters (temp eratur e, press ure, volum e, etc.)?
. C. II
: B. III · _@ I ·
~t ' s also calle d isorne t_ric / isovw "etr ic ?
: A. II . h I
1
, B. None D. III .
\ I

84 .
~1>B~5c~~
. r
~s at a const ant en tro p y .
C.
D.
II
I, II & III
I

'
Contin u e d on fage 9
 FHYSI ~IANS Licen sur e Examin a t ion
Satur ~ ay, Oc t o ber 30, 202 1 0 8 :0 0 a .m. - 10:00 a.m. Page 9
I
I

.BI OC HEM ISTRY

. ! SET A

85, 1
• ,ccurs witho ut a change in the intern al energy
L01 c . None
l B. II (§§Fi rr
I
Situa~ ion l]°, - Gene e.>cpre s~io ~, is the. proces s of produc in.9
· pro.t ein as an en cl
rocluc~ thr ough genetJ.c inform ation. Hmvev er ,· there are also
.on-pr otein coding genes produ cing functi onal RNAs instea d of
trotei n. ·
I

\ 86. ~he produ ction of a RNA · copy from a DNA strand is

9alled - - - - - - - - - , - - - -
. A. transd uction
, B. transl ation
' r-a ~rans ~ri~ti on
~ - inscri ption
\ ~ 87.
1 hich type of activa tor i s respo~ sible for the proces s above, which
9ne ribon ucleo tide at a time to an expand ing RNA strand ? · ~dds
I A. Oxida se c. Polym erase
( ~ Ribon ucleas e D. Hydro xylase
\ 88. · xampl es of non-p rotein -codin g genes are the follow ing, ~
.
A. messe nger RNA c. transf er RNA
/B. micro RNA D. riboso mal RNA
8 9 . In which of the follow ing condi tions do non-co dipg RNAs
si nifica nt role? pl~y a M::•ST
. ·
,~ Dlabe tes mellit us C. · second ary hypert ension
I
B. E·ssen ti al hypert ens ion D. Dyslip idemia
\ 90. ~~9J:ll_ atj O)L ~ e exp ressio1 ; is signif :.cant ly respon sible for the
·· f ~owi ng c;_,Ex_g~
[A) morph ogenes is . ·-.
~l
static evolut i onary status
. versa tility and adap~ ability / .
I D. cellu lar differ entiat ion
Si tuat ~on 12 - Amino acids (AA_y) can be protei nogen ic or
non-pr oteino genic and
tt,_ey carry out many impo.r ~ant biolog ical fu::icti ons in the body.

\ 91. wkich AA is · mainly an EXCITATORY neuro transm itter?

A. Adren o-carn itine
1

ta) Glutam ate ( glutam ic acid)

1 c. Hydro xypro line
, D. Gamm a-amin obutyr ic· acid
!

wl1.i.ch AA is an INHIBI TORY neuro transr nitt~r ?

[J:\) Gamm a-amin obutyr 1.c acid · .
· s. Bydro ½ypro line
: c. Glutam ate (gluta mic a6ici)
. D. Glycin e
·
93. which is a biosyn e t·1c precu rsor ~o-
th
crJo_-p·n,
~
,-r1' ns 1·11 red blood cells?
J'19
L
Glycin e .
·;1'3 , Hydro xypro line . ,
c. Glut~m ~t~ (gluta ~ic a~id),
D . Gamma -a;n1no butyr1 .c acid

\•/ 1:l i ch i!:I an impo~ tant compo nent of coi:i•nect:i ve. tissue collag en?
' A . Hydr oxy p rolin e , .
(If:-. Glutam a t ~ ( gll~tam ic a<;=id)
'"·c. Gamrn a- ann nobuty r ic ac .1. d .
o . Gly c i ne
 PHYS~ CIANS Li ce nsure Exam inatio n
Satu~ day, Page 10
Octo ber JO, 202 1 08 : 0 0 a .m. - lO :OO a.m.
I

~ -~~~c; l"JEMI ST F. V SET A

9 '5. !Whi.c:h AA is used in l ipi d tra n s p or U--

" A. Ly sine (9; Carn~ tine
\.. 1
E S-2r ine
-'.
· D. Prol ine
Sit uJ tion 13 __ Muscle s nee d enei:q y for cont racti
on. They may de,ri ve .i.t from: I.
·iGJ.y colys .is, or II. Kr eb ' s cycJ3 · . .
:whic h of the two sourc es d o t h e follow 1.ng pert~ in to?
9 6 . '. It/Th ey .is / are a seque nce of ten reac tions catal yzed by enzym
es leacli11g
i to form ation of pyru vic acid w;~th rele:i .se of free en~r gy.
A_ I
·
.
,,,...--1 IJ
I •
,- c. Neit her of these
~'..I I D. II
en. i High -ener .9y 1
mole cu les aden osine triph osph ate (ATP) and reduc
1nico ntina mide aden ine dinu cleo tide (NA~H) are ed
,reac tion ( s) .
forme d afte r this/ thes e
A.. I c. Neit her cf these
B. II (E; I, II
98. It/Th ey has/h ave a Prep arato ry (or Inves
tmen t) Phas e, wher ein ATP is
consu med and a Pay Off Phas e, wher ein ATP is
A. Neit her of these
prod uced .
C, II
!Q£~ I D. I, II
\
99. I!It I They prov .1' d'e ( s) prec u /rsors of certa in
amino acids tha.t are u::1~d in
jnume rou~ reac tions in the body .
! A. Neith e1: of these Q II
i B. I I II D. I
10 0. \The reac tions of this/ thes e energ y
sou= ce(s) are carri ed out by eigh t
\enzy mes that comp letel y oxid ize a ceta te a two carbo n mole cule) ,
. A. I C. II
I B. Neit her of thes a I, II
I