All the following are the functions of amniotic fluid but except:

A. Protects the fetus from injury

B. Protects against infection
C. Provide the nutrient for fetus
D. Allows the baby to move & develop properly
E. Helps control the temperature of the fetus
ANSWER:C

For greater risk for birth defects, the amniocentesis is generally offered to women
between:
A. 11th and 14th weeks of pregnancy
B. 15th and 20th weeks of pregnancy
C. 18th and 22th weeks of pregnancy
D. 10th and 12th weeks of pregnancy
E. 20th and 22th weeks of pregnancy
ANSWER:B

For genetic disease, the amniocentesis is offered at :

A. 1st trimester
B. 2nd trimester
C. any trimester
D. 3rd trimester
E. 2nd and 3rd trimester
ANSWER:B

All the following are the indications of amniocentesis but except:

A. Genetic disease or metabolic disorder
B. Open neural tube defects
C. Maternal age over 35 years
D. Fetal Demise
E. Risk of a sex-linked genetic disease
ANSWER:D

For open neural tube defects, the amniocentesis is offered at :

A. 2nd trimester
B. 1st trimester
C. any trimester
D. 3rd trimester
E. 2nd and 3rd trimester
ANSWER:A

All the following are the indications of amniocentesis of 3rd trimester but except:
A. Fetal lung maturity
B. Fetal infection
C. Rh disease
D. Risk of a sex-linked genetic disease
E. Treatment for polyhydramnios
ANSWER:D

To detect digestive anomalies, the biochemical dosage is:

A. Phenylalanine ammonia-lyase (PAL)
B. Alpha feto-protein (AFP)
C. Beta microglobulin
D. Alpha microglobulin
E. Human chorionic gonadotrophin
ANSWER:A

To detect the anomalies of nervous system, the biochemical dosage is:

A. Phenylalanine ammonia-lyase (PAL)
B. Alpha feto-protein (AFP)
C. Beta microglobulin
D. Alpha microglobulin
E. Human chorionic gonadotrophin
ANSWER:B

To detect the anomalies of urinary system, the biochemical dosage is:

A. Phenylalanine ammonia-lyase (PAL)
B. Alpha feto-protein (AFP)
C. Beta microglobulin
D. Alpha microglobulin
E. Human chorionic gonadotrophin
ANSWER:C

Which type of virus can find in amniotic fluid by amniocentesis?

A. Enterovirus
B. RSV virus
C. Adenovirus
D. Dengue virus
E. Rubella
ANSWER:E

Which type of parasite can find in amniotic fluid by amniocentesis?

A. Trichomonas vaginalis
B. Giardia
C. Entamoeba histolytica
D. Toxoplasmosis
E. Plasmodium
ANSWER:D

Risk of miscarriage for amniocentesis is:

A. 0.5-1%
B. 1-2%
C. 2-3%
D. 2.5-3%
E. 3.5-4%
ANSWER:B

Common germ caused infectious complication is:

A. Clostridium
B. Staphylococcus
C. Streptococcus
D. Gonococcus
E. Chlamydia
ANSWER:A

All the following are the complications of amniocentesis but except:

A. Failure of collection
B. Cramping
C. Bleeding
D. Fetal trauma
E. SARS-CoV-2 infection
ANSWER:E

All the following are the indications of amniocentesis of 2nd trimester but except:
A. Down syndrome
B. Spina bifida
C. Rh disease
D. Risk of a sex-linked genetic disease
E. Cystic fibrosis
ANSWER:C

All the following are the complications of amniocentesis but except:

A. Rh isoimmunization
B. HIV transmission
C. Infectious complications
D. Slowing of the baby's heart rate
E. Leaking of amniotic fluid
ANSWER:D

Chorionic villus sampling (CVS) is usually done between:

A. 8th and 10th weeks of pregnancy
B. 10th and 12th weeks of pregnancy
C. 14th and 18th weeks of pregnancy
D. 14th and 16th weeks of pregnancy
E. 2nd trimester
ANSWER:B

Chorionic villus sampling (CVS) does not provide information on neural tube
defects, maternal alpha-fetoprotein test will offered at:
A. between 16 to 18 weeks
B. between 14 to 16 weeks
C. between 18 to 20 weeks
D. between 22 to 24 weeks
E. between 26 to 28 weeks
ANSWER:A

All the following are the indications of chorionic villus sampling (CVS) but
except:
A. Maternal age over 35 years by the pregnancy due date
B. Metabolic disorder
C. Open neural tube defects
D. Sex-linked genetic disease
E. Abnormal cell-free DNA test
ANSWER:C

All the following are the contraindications of chorionic villus sampling (CVS) but
except:
A. Active STD infection
B. Carrying twins
C. Having uterine fibroids
D. Having anterverted uterus
E. Having tilted uterus
ANSWER:D

All the following are the elements of necessary 1st ultrasound before Chorionic
villus sampling (CVS) but except:
A. Embryonic vitality
B. Number of placenta
C. Number of fetus
D. Position of the uterus
E. Location of placenta
ANSWER:B

Chorionic villus sampling (CVS) transabdominal is performed at:

A. 10 weeks to term
B. 8 weeks to term
C. 12 weeks to term
D. 11 weeks to term
E. 13 weeks to term
ANSWER:A

Chorionic villus sampling (CVS) transcervical is performed at:

A. 10 weeks to term
B. 12 weeks to term
C. 10 weeks to 12 weeks
D. 12 weeks to 14 weeks
E. 13 weeks to 14 weeks
ANSWER:C

All the following are the characteristics of chorionic villus sampling (CVS)
transabdominal but except:
A. Placenta in lower 1/3rd
B. Placenta in upper 2/3rd
C. Difficult specially if placenta is posterior
D. Discomfort is greater
E. Fetal loss rate identical to amniocentesis
ANSWER:A

The incidence of limb reduction defects higher if CVS is performed at :

A. <6 weeks of pregnancy
B. <8 weeks of pregnancy
C. <9 weeks of pregnancy
D. <10 weeks of pregnancy
E. <11 weeks of pregnancy
ANSWER:C

Which one is the false positive of chorionic villus sampling (CVS) finding ?
A. Maternal cell contamination
B. Neural tube defects
C. Rh incompatibility
D. Congenital defects
E. Determining paternity
ANSWER:A

All the following are the complications of chorionic villus sampling (CVS) but
except:
A. Miscarriage
B. Infection
C. Bleeding
D. Rh isoimmunization
E. Limb reduction defects
ANSWER:D

The sufficient quantity of chorionic villus sampling (CVS) is :

A. 5 to 10mg of tissue
B. 2 to 3mg of tissue
C. 7 to 10mg of tissue
D. 8 to 10mg of tissue
E. 9 to 10mg of tissue
ANSWER:A

The chorionic villus sampling (CVS) of metabolic diseases is at :

A. 9 to 10 weeks of gestation
B. 11 to 12 weeks of gestation
C. 12 to 14 weeks of gestation
D. 14 to 18 weeks of gestation
E. 14 to 16 weeks of gestation
ANSWER:B

The cordocentesis should offered at:

A. After 18 weeks of gestation
B. After 16 weeks of gestation
C. After 14 weeks of gestation
D. After 15 weeks of gestation
E. After 17 weeks of gestation
ANSWER:A

Which antenatal diagnosis is higher risk of complications to the baby including

death than other procedures do?
A. Chorionic villus sampling (CVS)
B. Cordocentesis
C. Amniocentesis
D. Maternal biochemical test
E. Fetal ultrasound
ANSWER:B

All the following are the indications of fetal blood sampling but except:
A. Determine blood type
B. Diagnose possible fetal infections
C. Identify possible fetal anemia
D. Fetal lung maturity
E. Identify possible low platelet count
ANSWER:D

The risk of maternal blood collection of fetal blood sampling is:

A. 5%
B. 10 %
C. 3%
D. 1%
E. 2%
ANSWER:A

All the following are the complications of fetal blood sampling but except:
A. Passing maternal infection
B. Fetal-maternal bleeding
C. Limb reduction defects
D. Fetal bleeding
E. Slowing of the baby's heart rate
ANSWER:C

The PAPP-A test and Free β-hCG should offered at:

A. 8–10 weeks
B. 10–12 weeks
C. 11–14 weeks
D. 14–16 weeks
E. 16–18 weeks
ANSWER:C

Which one is not biochemical test at second trimester?

A. alpha-fetoprotein (aFP)
B. unconjugated estriol
C. inhibin A
D. inhibin B
E. hCG
ANSWER:D
All the following are the indications of alpha-fetoprotein test but except:
A. Fetal lung maturity
B. Down syndrome
C. Twins or multiple births
D. Miscalculation of due date
E. Neural tube defect
ANSWER:A

American Pregnancy Association says that all pregnant women should be offered an
AFP test sometime between:
A. 10th and 14th week
B. 15th and 20th week
C. 16th and 22th week
D. 16th and 20th week
E. 18th and 22th week
ANSWER:B

Which one is not exact related to maternal serum biochemistry for quadruple test of
Trisomy 21 ?
A. Free Beta hCG increased
B. AFP increased
C. unconjugated estriol (uE3) decreased
D. Inhibin A increased
E. AFP decreased
ANSWER:B

Twin-to-Twin Transfusion Syndrome (TTTS) is usually complication of :

A. monoamniotic monochorial twin pregnancy
B. biamniotic bichorial twin pregnancy
C. biamniotic monochorial twin pregnancy
D. monoamniotic bichorial twin pregnancy
E. biamniotic bichorial twin pregnancy (fused)
ANSWER:C

Twin-to-Twin Transfusion Syndrome (TTTS) is the result of:

A. Presence of unbalanced anastomoses in the placenta typically arterial-capillary
connections
B. Presence of unbalanced anastomoses in the placenta typically arterio-arterial
connections
C. Presence of unbalanced anastomoses in the placenta typically venous-venous
connections
D. Presence of unbalanced anastomoses in the placenta typically arterio-venous
connections
E. Presence of unbalanced anastomoses in the placenta typically capillary beds
connections
ANSWER:D

Twin-to-Twin Transfusion Syndrome (TTTS) is diagnosed based obstetric ultrasound

from:
A. 18 weeks of gestation
B. 16 weeks of gestation
C. 14 weeks of gestation
D. 12 weeks of gestation
E. 20 weeks of gestation
ANSWER:B

All the following are the characteristic of donor twin but except:
A. smaller
B. oligohydramnios
C. absent bladder
D. anemia
E. cardiomegaly
ANSWER:E

All the following are the characteristic of recipient twin but except:
A. Polycythemia
B. Hydrops fetalis
C. absent bladder
D. cardiomegaly
E. polyhydramnios
ANSWER:C

Which one is the standard treatment of Twin-to-Twin Transfusion Syndrome (TTTS) if

fetal age < 28 weeks?
A. Yag laser photocoagulation
B. Serial amniocentesis
C. One fetal lysis
D. Preterm delivery
E. C-section
ANSWER:A