leuvocorin

Drug Name Mechanism of action Indication Contraindication Side Effects Nursing consideration
Generic In the body, used to treat Not indicated in Common side During:
Name: artemether is malaria, a the scenario effects:  Advise patient to
Leucovorin metabolized into the blood  headach take the drug with
active metabolite infection e meal/milk for better
Class: metabolite caused by  feeling absorption
Antidote dihydroartemisinin. Plasmodium dizzy  Caution patient not
The drug works parasites.  loss of to take it with juice
Dose: against the appetite (grapefruit)
80 erythrocytic stages of  feeling  Advise patient not
mg/m2/20 h P. falciparum by tired to take the drug less
inhibiting nucleic acid  chills or more than
Route: and protein  fever instructed by the
IV synthesis. physician
Artemether is  Advise patient not
administered in to skip doses
combination with  Monitor vital signs
lumefantrine for  Monitor adequate
improved efficacy food consumption
 Assess patient for
improvement in
signs and symptoms
of malaria (fever,
chills, muscle pains,
headache)
periodically during
therapy.

After:
 Inform patient to
report side effects
 Advise patient to
report healthcare
provider if
symptoms/condition
did not improve.
 Monitor heart
rhythm.
 Monitor vital signs
 Inform patient to
take another dose of
the drug if
experienced
vomiting after 1 hr
of drug
 administration

References:

 rxwiki. (2012, September 7). Artemether & Lumefantrine. rxwiki. Retrieved December 12,
2021, from https://www.rxwiki.com/artemether-lumefantrine#side-effects.
 Farlex. (n.d.). Artemether-Lumefantrine. The Free Dictionary. Retrieved December 12, 2021,
from https://medical-dictionary.thefreedictionary.com/artemether-lumefantrine.
 Coartem: Uses, dosage, side effects, warnings. Drugs.com. (n.d.). Retrieved December 12, 2021,
from https://www.drugs.com/coartem.html.
 What is mastectomy? Breastcancer.org. (2020, October 29). Retrieved December 12, 2021, from
https://www.breastcancer.org/treatment/surgery/mastectomy/what_is.
 BRUNNER & SUDDARTH’S., (2018). Medical Surgical Nursing. Singapore: Elsevier.