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DOSAGE/ INDICATIONS/

NAME OF DRUG FREQ/ CLASSIFICATION MECHANISM OF CONTRA- SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
ROUTE/ ACTION INDICATIONS EFFECTS
SUPPLIED
GENERIC NAME Induction of Synthetic Misoprostol Indication GI GI BEFORE:
Misoprostol labor prostaglandin E1 binds to smooth Misoprostol is Nausea Diarrhea - Review the patient’s chart and doctor’s order
25 mcg/q3- analogue muscle cells in used off-label for Abdominal before administering the drug.  
6hr/intravagin the uterine lining a variety of Immune System pain - Assessing the patient’s general condition
BRAND NAME al/ to increase the indications in the Fever Vomiting and including observations. 
Cytotec, Arthrotec, suppository strength and practice of Chills - Explain to the patient the importance,
Mifegymiso frequency of obstetrics and CNS
dosage, and administration route of
Postpartum contractions as gynecology, GU Headache
Hemorrhage well as degrade including Miscarriage Misoprostol. 
600 collagen and medication Menstrual - Verify whether the patient is allergic to the
mcg/within 1 reduce cervical abortion, medical disorders contents of the drug. 
min of tone. management of - Check the medication visually for particles or
delivery/PO/t miscarriage, discoloration and discard properly if
ablet Misoprostol is a induction of labor, present. 
synthetic cervical ripening DURING:
Incomplete prostaglandin before surgical - Inform patient that misoprostol will cause
Abortion E1 analog that procedures, and spontaneous abortion. Women of childbearing
600 stimulates the treatment of age must be informed of this effect through
mcg/within 1 prostaglandin postpartum verbal and written information and must use
min of E1 receptors on hemorrhage. Due contraception throughout drug treatment. If
delivery/BUC parietal cells in to its wide- pregnancy is suspected, the woman should stop
/tablet the stomach to ranging taking misoprostol and notify her health care
reduce gastric applications in professional immediately.
acid secretion. reproductive AFTER:
Mucus and health, - Monitor improvements in GI symptoms (gastritis,
bicarbonate misoprostol is on heartburn, and so forth) to help document
secretion are the World Health whether drug therapy is successful in preventing
also increased Organization gastric damage or duodenal ulcers.
along with Model List of - In cases of NSAID-induced gastritis, implement
thickening of the Essential appropriate manual therapy techniques, physical
mucosal bilayer Medicines. This agents, and therapeutic exercises to reduce
so the mucosa article briefly musculoskeletal pain and decrease the need for
can generate reviews the aspirin and other NSAIDs.
new cells varied uses of - Advise patient to avoid alcohol and foods that
misoprostol in may cause an increase in GI irritation.
References: obstetrics and - If used with mifepristone to terminate pregnancy,
(n.d). gynecology. . inform patient that vaginal bleeding and uterine
misoprostol. cramping will probably occur. Bleeding or
Retrieved from Contraindication spotting occurs for an average of 9–16 days, but
Medscape may continue for more than 30 days. Instruct
https://reference Contraindicated patient to report any severe or unusual
.medscape.com/ in pregnant cramping, bleeding, or pelvic pain that extends
drug/cytotec- women to reduce beyond the expected time periods.
misoprostol- peptic ulcer risk - Instruct patient to report bothersome side
341995#91 from NSAIDs effects, including severe or prolonged headache,
menstrual irregularities, or GI problems (nausea,
Hypersensitivity diarrhea, vomiting, constipation, heartburn,
to misoprostol, flatulence, abdominal pain).
prostaglandins, - Document findings and refer to the physician. 
or prostaglandin
analogues

Use with caution


in women >35
years or heavy
smokers (these
patients were not
included in
clinical trials)

DOSAGE/ INDICATIONS/
NAME OF DRUG FREQ/ CLASSIFICATION MECHANISM OF CONTRA- SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
ROUTE/ ACTION INDICATIONS EFFECTS
SUPPLIED
GENERIC NAME

BRAND NAME

DOSAGE/ INDICATIONS/
NAME OF DRUG FREQ/ CLASSIFICATION MECHANISM OF CONTRA- SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
ROUTE/ ACTION INDICATIONS EFFECTS
SUPPLIED
GENERIC NAME

BRAND NAME

DOSAGE/ INDICATIONS/
NAME OF DRUG FREQ/ CLASSIFICATION MECHANISM OF CONTRA- SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
ROUTE/ ACTION INDICATIONS EFFECTS
SUPPLIED
GENERIC NAME

BRAND NAME

DOSAGE/ INDICATIONS/
NAME OF DRUG FREQ/ CLASSIFICATION MECHANISM OF CONTRA- SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
ROUTE/ ACTION INDICATIONS EFFECTS
SUPPLIED
GENERIC NAME

BRAND NAME

.
DOSAGE/ INDICATIONS/
NAME OF DRUG FREQ/ CLASSIFICATION MECHANISM OF CONTRA- SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
ROUTE/ ACTION INDICATIONS EFFECTS
SUPPLIED
GENERIC NAME

BRAND NAME

.
DOSAGE/ INDICATIONS/
NAME OF DRUG FREQ/ CLASSIFICATION MECHANISM OF CONTRA- SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
ROUTE/ ACTION INDICATIONS EFFECTS
SUPPLIED
GENERIC NAME

BRAND NAME

.
DOSAGE/ INDICATIONS/
NAME OF DRUG FREQ/ CLASSIFICATION MECHANISM OF CONTRA- SIDE EFFECTS ADVERSE NURSING RESPONSIBILITIES
ROUTE/ ACTION INDICATIONS EFFECTS
SUPPLIED
GENERIC NAME

BRAND NAME

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