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Epidemiology
Epidemiology
1-Epidemiolgy:- is the study of health in populations to understand the causes and patterns
of health and illness
2-Host:- refers to the human who can get the disease
3-Environment:- refers to extrinsic factors that affect the agent and the opportunity for
exposure
4-Diagnosis:- Diagnosis, or identifying the health problem, is done by taking a patient’s
history, conducting an examination, and pursuing further specific investigation as needed.
6-Health:- a state of complete physical, mental, and social well-being and not merely the
absence of disease or infirmity
7-Good health:- is a high level of wellbeing
8-Bad health:- is a lower level of wellbeing
9-Disease:- is an abnormal condition that affects a person and causes a disorder of a
structure or function.
10-Agent:- an infectious microorganism or pathogen, such as a virus, bacterium, or parasite
11-Reservoir:- is the habitat in which it normally lives, grows, and multiplies. Reservoirs
include humans, animals, and the environment.
12-Human Reservoir:- Diseases that are transmitted from person to person without
intermediaries include the sexually transmitted diseases, measles, mumps, streptococcal
infection, and many respiratory pathogens
13-Carriers:- persons who are infectious but have subclinical disease
14-Animal Reservoirs:- Many of these diseases are transmitted from animal to animal, with
humans as incidental hosts
15-Zoonosis:- an infectious disease that is transmissible under natural conditions from
vertebrate animals to humans.
16-Asymptomatic Carriers:- are those who never experience symptoms despite being
infected.
17-Incubatory Carriers:- are those who can transmit the agent during the incubation period
before clinical illness begins
18-Convalescent Carriers:- are those who have recovered from their illness but remain
capable of transmitting the illness to others
19-Chronic Carriers:- are those who continue to harbor a pathogen such as hepatitis B
virus or Salmonella typhi, the causative agent of typhoid fever, for months or even years
after their initial infection.
20-Environmental Reservoir:- Plants, soil, and water are also reservoirs for some
infectious agents
21-Portal of Exit:- A portal of exit is the path by which a pathogen leaves its host.
22-Vehicles:- that may indirectly transmit an infectious agent include food, water, biologic
products (blood), and fomites (inanimate objects such as handkerchiefs, bedding, or surgical
scalpels)
23-Vectors:- are living organisms that can transmit infectious diseases between humans
and from animals to humans
24-Mechanical Transmission:- are files carrying Shigella on their appendages and fleas
carrying Yersinia pestis, the causative agent of plague, in their gut.
25-Biological Transmission:- the vector may support growth or changes in the agent.
26-Portal of Entry:- the manner in which a pathogen enters a susceptible host. The portal of
entry must provide access to tissues in which the pathogen can multiply or a toxin can act.
27-Specific Immunity:- protective antibodies that are directed against a specific agent.
Such antibodies may develop in response to infection, vaccination, or toxoid
28-Physical environment:- Safe water and clean air, healthy workplaces, and safe houses,
communities, and roads all contribute to good health.
29-Primary prevention:- Preventing the development of disease by reducing exposure to
disease-causes agents or by immunization denotes intervention before disease developed.
30-Secondary prevention:- Detecting disease at an early stage, such as by screening,
takes place during the preclinical phase of an illness, that is, after the disease has
developed, but before clinical signs and symptoms have appeared.
31-Tertiary Prevention:- Treating clinically ill individuals to prevent complications of the
illness, including death of the patient.
32-Rehabilitation:- Assisting the handicapped person who was not completely cured
improves their quality of life.
33-Health promotion:- is the process of empowering people to increase control over their
health and its determinants to improve their health.
34-Sporadic:- a disease that occurs infrequently and irregularly.
35-Endemic:- the constant presence and/or usual prevalence of a disease or infectious
agent in a population within a geographic area.
36-Epidemic:- an increase, often sudden, in the number of cases of a disease above what
is normally expected in that population in that area.
37-Outbreak:- carries the same definition of epidemic but is often used for a more limited
geographic area.
38-Pandemic:- an epidemic that has spread over several countries or continents, usually
affecting a large number of people
39-Emerging diseases:- a disease that occurs for the first time in a certain country.
40-Re- emerging diseases:- a disease that was eliminated in a certain country and then
reappears
41-Incidence rate:- the estimated rate of disease occurrence (newly diagnosed problems)
𝐍𝐮𝐦𝐛𝐞𝐫 𝐨𝐟 𝐧𝐞𝐰 𝐜𝐚𝐬𝐞𝐬 𝐧𝐨𝐭𝐢𝐟𝐢𝐞𝐝
for a given year and specific location = ×1,000
𝐌𝐢𝐝𝐲𝐞𝐚𝐫 𝐩𝐨𝐩𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐚𝐭 𝐫𝐢𝐬𝐤
42-Prevalence rate:- The estimated rate of all diseased cases (newly diagnosed and those
𝐍𝐮𝐦𝐛𝐞𝐫 𝐨𝐟 𝐚𝐥𝐥 𝐩𝐫𝐞𝐬𝐞𝐧𝐭 𝐜𝐚𝐬𝐞𝐬
under treatment) for a given year and specific location = ×1,000 .
𝐌𝐢𝐝𝐲𝐞𝐚𝐫𝐬 𝐩𝐨𝐩𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐚𝐭 𝐫𝐢𝐬𝐤
43-Morbidity Rate:- The rates that measure disease
44-Mortality Rate:- The rates that measure death
45-Diphtheria:-is an upper respiratory tract illness caused by Corynebacterium diphtheria
infection
46- Hepatitis:-infection of the liver with specific viruses such as hepatitis A , B , C virus.
47-Total Fertility Rate:- gives a figure for the average number of children that would be
born per woman if all women lived to the end of their childbearing years and bore children
according to a given fertility rate at each age—age-specific fertility rates.
48-Public Health Surveillance:- Public health surveillance is the ongoing, systematic
collection, analysis, interpretation, and dissemination of health data to help guide public
health decision making and action.
49-Evaluation:- is process of determining, as systematically and objectively as possible, the
relevance, effectiveness, efficiency, and impact of activities with respect to established goals
50-Effectiveness:- the ability of a program to produce the intended or expected results in
the field
51-Efficiency:- the ability of the program to produce the intended results with a minimum
expenditure of time and resources
52-Linkages:-
53-Attributable risk:- How much of the disease that occurs that can be attributed to a
certain exposure. The amount or proportion of disease incidence (or disease risk) that can
be attributed to a specific exposure
55-Demography:- is the science that deals with population characteristics or distribution.
“Demos” means people, while “graphy” means to write or describe.
56-A census:- is an accurate method for determining size & characteristics of a population.
57-The base width of population pyramid:- gives an idea about the proportion of young
individuals in a population.
58-The height of the pyramid:- that people live longer, while a short height means that the
average life in a population is short.
59-The top width of PP:- indicates the size of the population in the old age group.
60-The symmetry of the pyramid:- the left side of the pyramid is similar to the right side;
that is, the age distribution among males is similar to that of females
2)Give an short account on:-
1-The population pyramid characteristics?
A)The base width gives an idea about the proportion of young individuals in a population.
In Egypt the base is wide, which indicates a large proportion of children.
B)The top width indicates the size of the population in the old age group. In Egypt, the
width is narrow (tapering end of pyramid), which means that the proportion of the elderly in
the population is small. In other countries, the top is relatively wide, which means that the
elderly make up a large proportion of the population.
C)The height of the pyramid means that people live longer, while a short height means that
the average life in a population is short. The Egyptian pyramid is short.
D)The symmetry means that the left side of the pyramid is similar to the right side; that is,
the age distribution among males is similar to that of females. This case is present in Egypt.
E)The shape sides usually narrow smoothly as age advances because of continuous death.
However, the sides may have depressions because of an unusually high number of deaths,
2-Core epidemiologic functions?
1-Public Health Surveillance:-Public health surveillance is the ongoing, systematic
collection, analysis, interpretation, and dissemination of health data to help guide public
health decision making and action.
2-Field Investigation:-As noted above, surveillance provides information for action. One of
the first actions that results from a surveillance case report or report of a cluster is
investigation by the public health department.
3-Analytic Studies:-Surveillance and field investigations are usually sufficient to identify
causes, modes of transmission, and appropriate control and prevention measures. But
sometimes analytic studies employing more rigorous methods are needed. and analytic
studies evaluating the credibility of those hypotheses.
4-Evaluation:-is the process of determining, as systematically & objectively as possible, the
relevance, effectiveness, efficiency, & impact of activities with respect to established goals.
a)Effectiveness:- refers to the ability of a program to produce the intended or expected
results in the field; effectiveness differs from efficacy, which is the ability to produce results
under ideal conditions. b)Efficiency:- refers to the ability of the program to produce the
intended results with a minimum expenditure of time and resources.
5-Linkages:-field epidemiology is often said to be a “team sport.” During an investigation, an
epidemiologist usually participates as either a member or the leader of a multidisciplinary
team. Other team members may be laboratories, sanitarians, infection control personnel,
nurses or other clinical staff, and, increasingly, computer information specialists. To promote
current and future collaboration, the epidemiologists need to maintain relationships with staff
of other agencies and institutions.
6-Policy Development:-The definition of epidemiology ends with the following phrase:
“…and the application of this study to the control of health problems.” Epidemiologists who
understand a problem and the population in which it occurs are often in a uniquely qualified
position to recommend appropriate interventions.
3-The Health Promotion activities?
1-Policies and interventions to address tobacco, alcohol, physical activity, and diet
2-Dietary and nutritional intervention to appropriately tackle malnutrition, defned as a
condition that arises from eating a diet in which certain nutrients are lacking or in the wrong
proportions or intake is too high
3-Policies and health services interventions to address mental health and substance abuse
4-Strategies to promote sexual and reproductive health, including through health education
and increased access to sexual and reproductive health and family planning services
5-Strategies to tackle domestic violence, including public awareness campaigns; treatment
and protection of victims; and linkage with law enforcement and social services
4-Secondary prevention activities?
1-Population-based screening programs for early detection of diseases
2-Provision of maternal and child health programs, including screening and prevention
of congenital malformations
3-Provision of medicines to control risk factors, such as hypertension
5-Natural history of a disease or health problem?
A)No disease
B)Preclinical phase (biological onset of disease = pathological phase)
C)Clinical phase
1-Symptoms (individual feeling) 2-Signs (physician diagnoses)
3-Treatment (physician recommends treatment, such as drugs, surgery, or other therapies)
D)Outcome phase
1-Complete recovery (cure) 2-Death
2-Recovery, but with remaining pathology or handicap.
-Three factors determine the disease/health problem process (epidemiological determinants)
and make up the epidemiological triad:
1-Host 2-Causative agent 3-Environmental factors
6-Types of prevention?
A)Primary prevention:-Preventing development of disease by reducing exposure to
disease-causing agents or by immunization denotes intervention before disease developed.
B)Secondary prevention:- Detecting disease at an early stage, such as by screening, takes
place during the preclinical phase of an illness, that is, after the disease has developed, but
before clinical signs and symptoms have appeared.
C)Tertiary prevention:- Treating clinically ill individuals to prevent complications of the
illness, including death of the patient.
D)Rehabilitation:- Assisting the handicapped person who was not completely cured
improves their quality of life
7-The measurements of mortality rate?
1-The crude death rate for a given year and specific location is calculated as follows:
𝑵𝒖𝒎𝒃𝒆𝒓 𝒐𝒇 𝒂𝒍𝒍 𝒅𝒆𝒂𝒕𝒉𝒔
Crude death rate= ×1,000
𝑴𝒊𝒅𝒚𝒆𝒂𝒓 𝒑𝒐𝒑𝒖𝒍𝒂𝒕𝒊𝒐𝒏 𝒂𝒕 𝒓𝒊𝒔𝒌
2- A cause-specific death rate is important to show the disease’s behavior, time, place, &
𝑵𝒖𝒎𝒃𝒆𝒓 𝒐𝒇 𝒄𝒂𝒖𝒔𝒆−𝒔𝒑𝒆𝒄𝒊𝒇𝒊𝒄 𝒅𝒆𝒂𝒕𝒉𝒔
the people at risk Cause-specific death rate= ×1000
𝑴𝒊𝒅𝒚𝒆𝒂𝒓 𝒑𝒐𝒑𝒖𝒍𝒂𝒕𝒊𝒐𝒏 𝒂𝒕 𝒓𝒊𝒔𝒌
3- Age-specific death rates are useful to draw the attention to certain age groups:
𝑵𝒖𝒎𝒃𝒆𝒓 𝒐𝒇 𝒅𝒆𝒂𝒕𝒉𝒔 𝒓𝒆𝒄𝒐𝒓𝒅𝒆𝒅 𝒇𝒐𝒓 𝒊𝒏𝒅𝒊𝒗𝒊𝒅𝒖𝒂𝒍𝒔 𝒊𝒏 𝒂 𝒄𝒆𝒓𝒕𝒂𝒊𝒏 𝒂𝒈𝒆 𝒈𝒓𝒐𝒖𝒑
Age-specific death rate= ×1000
𝑴𝒊𝒅𝒚𝒆𝒂𝒓 𝒑𝒐𝒑𝒖𝒍𝒂𝒕𝒊𝒐𝒏 𝒐𝒇 𝒕𝒉𝒆 𝒔𝒂𝒎𝒆 𝒂𝒈𝒆 𝒂𝒕 𝒓𝒊𝒔𝒌
4- The most useable health care indicator infant mortality rate in a given year in a specific
𝑵𝒖𝒎𝒃𝒆𝒓 𝒐𝒇 𝒅𝒆𝒂𝒕𝒉𝒔 𝒓𝒆𝒄𝒐𝒓𝒅𝒆𝒅 𝒇𝒐𝒓 𝒄𝒉𝒊𝒍𝒅𝒓𝒆𝒏 𝒊𝒏 𝒕𝒉𝒆 𝒇𝒊𝒓𝒔𝒕 𝒚𝒆𝒂𝒓 𝒐𝒇 𝒍𝒊𝒇𝒆
location: infant mortality = 𝑵𝒖𝒎𝒃𝒆𝒓 𝒐𝒇 𝒓𝒆𝒈𝒊𝒔𝒕𝒆𝒓𝒆𝒅 𝒍𝒊𝒗𝒆 𝒃𝒊𝒓𝒕𝒉𝒔
×1000
5)Secondary (2)Person who show no symptoms or have undiagnosed infections may be able to
Prevention transmit infection to others.
6)Host (5) Involves identifying people in whom a disease process has already begun but
the clinical signs and symptoms of the illness have not yet developed.
7)Outbreak (6)Refers to the human who can get the disease.
8)surveillance (8)Is ongoing systematic, collection, analysis, interpretation and dissemination of
health data to help guide public health decision making and action
1)Public health (7)The estimated rate of disease occurrence \(newly diagnosed problems) for a given
surveillance year and specific location
2)Environmental (6)Refers to the constant presence and/or usual prevalence of a disease or infectious
factors include agent in a population within a geographic area.
3)Convalescent (1)Is the ongoing, systematic collection, analysis, interpretation, & dissemination of
Carriers health data to help guide public health decision making & action.
4)Primary (3)Are those who have recovered from their illness but remain capable of transmitting
Prevention the illness to others
5)Confirmed (2)Physical factors such as geology, Biological factors such as insects, and
Case Socioeconomic factors, such as crowding
6)Endemic (4)Preventing the development of disease by reducing exposure to disease-causing
agents or by immunization denotes intervention before disease has developed.
7)the incidence (5)In addition to evidence pointing to a suspected or probable case, a laboratory
rate finding that provides the evidence of infection
1)Attributable Risk (3)Is dependent on studying the person, place, and time.
2)Environment (4)Are those who never experience symptoms despite being infected.
3)The distribution (7) Refers to a disease that was eliminated in a certain country and then
of any disease reappears.
4)healthy Carriers (1)How much of the disease that occurs can be attributed to a certain exposure
5)The determinants (2)Refers to extrinsic factors that affect the agent and the opportunity for
of health exposure.
6)A census (5)Include: The social and economic environment, the physical environment and
an individual person’s characteristics and behaviors
7)Re-Emerging (6)Is an accurate method for determining size & characteristics of a population.
شكرا بجد لكل إلي تعب معانا وساعدنا ورمضان كريم وكل سنة وانتوا طيبين
وبالنجاح إن شاء هللا