KOAL A TM

Automated detection of osteoarthritis signs

on standing knee radiographs

INTENDED USE
IB Lab KOALA is a fully-automated image processing so ware intended to aid medical professionals in
detecting signs of knee osteoarthritis (OA) based on standard joint parameters and OARSI criteria of standing
radiographs of the knee. The measurements include:

Minimum joint space width

Sclerosis signs according to OARSI criteria
Joint space narrowing according to OARSI criteria
Osteophytes based according to criteria
Osteoarthritis grades based on Kellgren & Lawrence

YOUR BENEFITS
Fully automated AI-based measurements
Consistent and reproducible results
Works with computed (CR) or directly digital (DX) images
PACS agnostic and integrated seamlessly into existing workflows
Results are displayed in your DICOM Viewer
No extra hardware required

RESULTS
“Exact diagnosis and reproducible follow-up
92% 93% 23% exams of osteoarthritis is the basis for a
PRECISION ACCURACY INCREASE preventive and successful osteoarthritis
Detecting Physicians agreement therapy. Software-based methods can assist
Detecting joint
osteoarthritis space narrowing rate to gold-standard* the physician in the therapy management
and adjustment process.”
* Measured by scoring orthopaedic surgeons with and without KOALA
assistance against a large longitudinal study based on US data [1]
S.N. MD, Professor of Orthopedics, KOALA user

SUPPORTING YOUR MEDICAL PRACTICE

Clinical Relevance Flexible Integration Easy access

Combining standardization,
automation and digitalization
for reproducible results, and
potentially better agreement
levels and patient outcome
Our tools can be integrated
seamlessly into your existing IT
platform, and adapted to your
workflows to support your
practice
Results are calculated within
seconds, stored in your PACS
available in your DICOM viewer
as printable PDF reports for the
referring pyhsicians

[1] Nehrer S, Ljuhar R, Steindl P, et al. Automated Knee Osteoarthritis Assessment Increases Physicians’ Agreement Rate and Accuracy: Data from the
Osteoarthritis Initiative [published online ahead of print, 2019 Nov 24]. Cartilage. 2019;1947603519888793. doi:10.1177/1947603519888793

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com
ZERO CLICKS, ZERO WORKFLOW CHANGES
Images are automatically forwarded from your PACS to the IB Lab AI platform, and annotations are attached
to the original study as a DICOM overlay and detailed printable reports. The results can be stored in your PACS
and viewed in any DICOM viewer.

X-RAY PACS KOALA TM DICOM Viewer

On premise or HIPAA - Compliant Cloud

DICOM overlay and report added to patient record On screen and printable report

Your
logo
here

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com
PANDA TM

Automated estimation of paediatric bone IN THE U.S.

age and growth potential for children AVAILABLE FOR
RESEARCH ONLY

INTENDED USE
IB Lab PANDA is a radiological image processing so ware intended to aid medical professionals in the
estimation of paediatric bone age and growth potential from hand radiographs of children aged between 36
months and 172 months (girls) or 192 months (boys).

Paediatric bone age according to Greulich & Pyle

Delayed / advanced bone age patient status
Height estimation according to Bayley & Pinnau
Prospective height calculation according to
Bayley & Pinnau
Growth potential achieved

YOUR BENEFITS
Fully automated AI-based measurements
Consistent and reproducible results
Works with computed (CR) or directly digital (DX) images
PACS agnostic and integrated seamlessly into existing workflows
Results are displayed in your DICOM Viewer
No extra hardware required

RESULTS “PANDA reduces the time spent per case

and increases the consistency of readings.
± 4.4 6.2 ± 2.5 The immediate reports fit perfectly in the
workflow and allow me to offer better
MONTHS SECONDS CENTIMETER
services to my referring physicians.”
Bone age mean Average Std. deviation for
absolute deviation* analysis time estimated height** N.W. MD, Professor of Diagnostic Radiology,
* Results from a validation study based on the dataset from [1] PANDA user
** Based on Bayley-Pinneau [2]

SUPPORTING YOUR MEDICAL PRACTICE

Clinical Relevance Flexible Integration Easy access

Combining standardization,
automation and digitalization
for reproducible results, and
potentially better agreement
levels and patient outcome
Our tools can be integrated Results are calculated within
seamlessly into your existing IT seconds, stored in your PACS
platform, and adapted to your available in your DICOM viewer
workflows to support your as printable PDF reports for the
practice referring pyhsicians

[1] Halabi, Safwan S et al. “The RSNA Pediatric Bone Age Machine Learning Challenge.” Radiology vol. 290,2 (2019): 498-503. doi:10.1148/radiol.2018180736
[2] Bayley, N., & Pinneau, S. R. (1952). Tables for predicting adult height from skeletal age: revised for use with the Greulich-Pyle hand standards. The Journal of
Pediatrics, 40(4), 423–441. doi:10.1016/s0022-3476(52)80205-7

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com
ZERO CLICKS, ZERO WORKFLOW CHANGES
Images are automatically forwarded from your PACS to the IB Lab AI platform, and annotations are attached
to the original study as a DICOM overlay and detailed printable reports. The results can be stored in your PACS
and viewed in any DICOM viewer.

X-RAY PACS PANDA TM DICOM Viewer

On premise or HIPAA - Compliant Cloud

DICOM overlay and report added to patient record On screen and printable report

Your
logo
here

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com
L AM A TM

Fully automated complete leg annotation NOT FOR SALE /

AVAILABLE FOR
so ware powered by Artificial Intelligence
RESEARCH ONLY

INTENDED USE
IB Lab LAMA is a radiological fully-automated image processing so ware for computed (CR) and digital
(DX) images intended to aid medical professionals in the measurement of preoperative leg geometry to aid
detection of presence or absence of deformities based on stitched standing AP radiographs of the leg of
adult humans.

Anatomical and mechanical angles according to Paley

Anatomic mechanical angle (AMA)
Mikulicz-Line
Length of tibia, femur and leg

YOUR BENEFITS

Fully automated AI-based measurements

Consistent and reproducible results
Works with computed (CR) or directly digital (DX) images
PACS agnostic and integrated seamlessly into existing
workflows
Results are displayed in your DICOM Viewer
No extra hardware required

RESULTS

<60 100%
SECONDS REPRODUCIBLE

To measure and Measurements

report findings on the image

SUPPORTING YOUR MEDICAL PRACTICE

Clinical Relevance Flexible Integration Easy access

Combining standardization,
automation and digitalization
for reproducible results, and
potentially better agreement
levels and patient outcome
Our tools can be integrated
seamlessly into your existing IT
platform, and adapted to your
workflows to support your
practice
Results are calculated within
seconds, stored in your PACS
available in your DICOM viewer
as printable PDF reports for the
referring pyhsicians

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com
ZERO CLICKS, ZERO WORKFLOW CHANGES
Images are automatically forwarded from your PACS to the IB Lab AI platform, and annotations are attached
to the original study as a DICOM overlay and detailed printable reports. The results can be stored in your PACS
and viewed in any DICOM viewer.

X-RAY PACS LAMA TM DICOM Viewer

On premise or HIPAA - Compliant Cloud

DICOM overlay and report added to patient record On screen and printable report

So ware Supported adult Full Leg Measurement

ImageBiopsy Lab LAMA Full Leg Measurement Patient

Your
logo
here

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com
HI PPO TM

Automated pre-operative measurement NOT FOR SALE /

AVAILABLE FOR
of hip and pelvic morphology
RESEARCH ONLY

INTENDED USE
IB Lab HIPPO is a fully-automated image processing so ware intended to aid medical professionals by providing
an overview and measurements of the hip and pelvic morphology of a patient. This parameters are the basis for
the preoperative diagnosis of common hip pathologies.

Presence/absence of Dysplasia and Femoral-Acetabular

Impingement (FAI) based on the Lateral Center-Edge Angle
(LCE), according to the Ogata method
Presence/absence of Coxa Vara / Valga based on the Corpus-
Collum Diaphysen (CCD) angle
Measurement of height differences and orthograde angle of
the femoral heads for evaluation of pelvic obliquity
Quality assessment of AP pelvic radiographs. Automated
correction of measurements caused by sub-optimal patient
positioning

PLANNED FEATURES

Sharp angle Tönnis angle Kellgren & Lawrence (KL) Hip joint space
Osteoarthritis width (JSW)

YOUR BENEFITS
Fully automated AI-based measurements
Consistent and reproducible results
Works with computed (CR) or directly digital (DX)
images
Results are displayed in your DICOM Viewer
No extra hardware required
PACS agnostic and integrated seamlessly into
existing workflows

SUPPORTING YOUR MEDICAL PRACTICE

Clinical Relevance Flexible Integration Easy access

Combining standardization,
automation and digitalization
for reproducible results, and
potentially better agreement
levels and patient outcome
Our tools can be integrated
seamlessly into your existing IT
platform, and adapted to your
workflows to support your
practice
Results are calculated within
seconds, stored in your PACS
available in your DICOM viewer
as printable PDF reports for the
referring pyhsicians

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com
ZERO CLICKS, ZERO WORKFLOW CHANGES
Images are automatically forwarded from your PACS to the IB Lab AI platform, and annotations are attached
to the original study as a DICOM overlay and detailed printable reports. The results can be stored in your PACS
and viewed in any DICOM viewer.

X-RAY PACS HIPPO TM DICOM Viewer

On premise or HIPAA - Compliant Cloud

DICOM overlay and report added to patient record On screen and printable report

Your
logo
here

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com
I ma g e B io ps y Lab
Beyond Diagnostics

ImageBiopsy Lab is developing a novel, AI-supported modular MSK so ware platform for standardized,
objective and automated analysis of medical images. Our tools can perform time-consuming and low-cognitive
routine tasks, to support your expertise and giving you more time for what matters most, your patients.

POWERED BY DEEP LEARNING

Our Machine Learning (ML) models are created based on image annotations done by medical professionals.
We can use this information to create constantly learning algorithms that automatically measure anatomical
distances, angles and volumes, and detect anomalies and lesions for you to review.

AI MODEL DEVELOPMENT AI MODEL IN PRODUCTION

CURATED MODEL TRAINING MODEL DEPLOYMENT AND

MEDICAL DATA AND TUNING VALIDATION MONITORING

Data selection Network architecture Performance evaluation Use in clinical practice

Data management Training framework Clinical validation Annotation of new data
Annotation pipelines Technology development Risk management Continuous monitoring

FROM IDEAS TO REGULATORY COMPLIANCE

We are customer-driven and follow a user-centered methodology in order to create solutions defined by
your needs. The excellence of our products is achieved by having a strong focus on Quality Management
and following the best practices for Machine Learning and So ware Development.

PROBLEM DATA SOLUTION PRODUCT CERTIFICATION

IDENTIFICATION GATHERING PROTOTYPE DEVELOPMENT AND RELEASE

Customer feedback Scientific Collaborations Reusable models FDA / CE

Literature research Commercial data sources Modular architecture Good practices
Focus groups Annotation pipelines Easy deployment Performance monitoring

A GROWING PLATFORM
IB Lab Zoo is a constantly evolving platform of AI-powered MSK radiology tools. Our products include:

Knee Ostheoarthritis (KOALATM) Hip deformities and positioning (HIPPO TM) - Research only
Pediatric bone age (PANDATM) Full leg angles and measurements (LAMATM) - Research only

© 2020 IB Lab GmbH www.imagebiopsylab.com +43 1 9051206 mail@imagebiopsy.com

sales@imagebiopsy.com