Professional Documents
Culture Documents
Review Sheet-Introduction Final
Review Sheet-Introduction Final
E. Blood Glucose
a. OGTT: Oral Glucose Tolerance Test
a. Measure fasting plasma
glucose and 2 hours after 75g
of glucose
b. Most sensitive, easy to
perform
b. HBA1C
a. Reflects average blood
glucose of prior 9-12 weeks
b. Can be measured anytime, no
need for fasting
c. Can be altered by other
conditions: CKD, sickle cell
trait etc
c. C Peptide:
a. helps differentiates between
Type 1 & Type 2
b. Increased: indicates insulin
resistance and
hyperinsulinemia→ T2DM
c. Decreased: Indicates an
absolute insulin deficiency→
T1DM
F. Basic Metabolic Panel ● D-Dimer - fibrin degradation
● The 4 Electrolytes: product, valuable in diagnosis of
➢ Sodium, Potassium, Bicarbonate, DVT
Chloride
➢ Derangements seen in
hypovolemia/ dehydration, kidney
disease, congestive heart failure,
alkalosis, acidosis
● Calcium - to monitor CKD and
parathyroid disease
● Glucose - to monitor blood sugar
● Blood urea nitrogen (BUN) -
elevated in kidney disorders or
congestive heart failure
● Creatinine - also elevated in kidney
H. Other important tests:
disorders. High levels of creatinine
in the blood and low levels in the ● Liver Function Tests:
urine indicates a kidney disease or ➢ AST (SGOT), ALT (SGPT), ALP,
decreased renal function. In Albumin and total protein,
general, high levels of creatinine in Bilirubin, GGT, LD, AST/ALT
blood and low levels in urine ratio
indicate kidney disease or another ➢ Derangements indicate liver
condition that affects kidney diseases, cholestasis, hepatitis, etc
function. These include: ➢ Isolated rise of ALP indicates non-
Autoimmune diseases, Bacterial hepatobiliary pathology like bone
infection of the kidneys, Blocked metastases or primary bone tumors,
urinary tract, Heart failure, bone fractures, or vitamin D
Complications of diabetes deficiency
➢ Monitor the effects of certain
hepatotoxic medications.
● Renal Function Tests - BUN,
creatinine, eGFR
● Thyroid function Test - T3, T4,
TSH
G. Coagulation Studies:
● PT, PTT
○ Prothrombin, Thromboplastin -
Proteins synthesised by the liver
○ Diagnosis of liver disease,
thrombophilia, hemophilia I. Microbiology:
○ Pre-operative tests ● Blood culture and sensitivity
● INR - Helps in monitoring the dose - To detect the presence of
of anticoagulants pathogens in the blood
- Direct treatment to be more
microbe-specific
- Check the sensitivity of microbes
to a certain antimicrobial
● Throat swab, Nasal or
Nasopharyngeal Swab
- To detect the presence of
pathogens at the respective location
● Sputum smear – mainly used in the
context of TB
J. Immunology:
● Immunoglobulins
- Allergies -
- Autoimmune diseases like lupus,
celiac disease, JIA
- Infections: e.g. IgG and IgM for
Measles
Imaging:
X-Ray:
Advantages Disadvantages
Cheap and widely available Does not provide resolution for complex illness.
Very short time to acquire results (<5 mins) It does not provide 3D information.
Non-invasive and painless Bones can block significant diagnostic data as it
Portable, so can be used to image people who cannot absorbs the radiation.
move They do not interact very strongly with lighter
Favored modality for: Bone Fracture, Pneumothorax, elements.
Pneumonia, Bowel Obstruction, etc. Due to its radiation, it mutates cells which causes
ionisation. This often leads to cancer.
CT Scan:
Advantages Disadvantages
Higher contrast resolution. Hence it can distinguish Expensive for routine clinical use.
tissues having differences of less than 1% in their Exposure to much higher dose of ionizing radiation
physical densities. than X-ray so chance of cancer in the future.
More affordable and quicker than MRII. Not portable, so work needed to bring patient to the
Motion artifacts are of less concern in CT scan than radiology wing in the hospital.
MRI. More time consuming than X-Rays.
Favored modality for: Brain Hemorrhage,
Contusions, cancer (All organs)
Ultrasound:
Advantages Disadvantages
Absolutely no Ionizing radiation, safe to use in An Ultrasound technician needs to have a lot more
pregnant women. training to master US.
Portable, able to be used anywhere and on less Bone blocks US waves. As such imaging of the spine
mobile patients is increasingly difficult with increasing age.
Widely accessible Artefacts are common. If a structure can only be seen
Good resolution. in one plane it is likely to be an artefact.
Favored modality for: Pregnant women, Baby, Increased depth means a lower frequency is required
Cannulation, Ascites, etc. for optimal imaging. As a consequence, there is a
lower resolution.
MRI Scan:
Advantages Disadvantages
No ionizing radiation, safe to use on all individuals Very expensive for the general population
Provides better soft tissue contrast for tendons, Long time to obtain results, thus very slow
cartilage, heart and brain. Motion artifacts can distort image, thus patient needs
Provides information about blood circulations so to lay still
useful in the diagnosis of blood vessel related Patient can become claustrophobic due to tiny space.
disorders. Loud banging noises make for an unpleasant session.
Favored modality for: Brain cancers, Cartilage and Not good for emergencies
tendon disorders, Heart valve dysfunction.
General Warning Signs § ≤ 3: require immediate
resuscitation
A. Neonatology
a. Signs
§ Fast
breathing
§ Persistent
cyanosis of the
skin
§ Grunting,
wheezing,
whistling while
breathing
§ Flaring of
nostrils or
retraction of ribs during breathing
§ Yellowing of the sclera or the skin
that worsens over time (see below)
§ Crying or irritability that cannot be
calmed
§ Excessive sleepiness
§ Fever
§ No bowel movement in the first 48
hours
§ No urine in the first 24 hours B. General Surgery
a. Shock is the most common
emergency that is encountered.
§ Fluid Resuscitation is the aim of
the game here and understand
the cause of the shock and
rectify it.
b. Use the Glasgow coma scale to
check patient mental status prior to
encounter and operation
b. APGAR Scoring