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  • Febrile Seizure

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    Jaleah Gwyneth Fernandez Edullantes
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    This document discusses predisposing and precipitating factors for complex febrile seizures in pediatric patients and the treatment pathway for pediatric community acquired pneumonia. It notes that complex febrile seizures most commonly affect children between 6 months and 3 years old and can be caused by genetic or developmental defects. Pneumonia is usually caused by inhalation or aspiration of pathogens and causes systemic inflammation and lung damage. Both conditions are treated with medications, with febrile seizures treated using medications like midazolam and pneumonia treated initially using bronchodilators along with antibiotics.

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    FEBRILE SEIZURE

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    This document discusses predisposing and precipitating factors for complex febrile seizures in pediatric patients and the treatment pathway for pediatric community acquired pneumonia. It notes that complex febrile seizures most commonly affect children between 6 months and 3 years old and can be caused by genetic or developmental defects. Pneumonia is usually caused by inhalation or aspiration of pathogens and causes systemic inflammation and lung damage. Both conditions are treated with medications, with febrile seizures treated using medications like midazolam and pneumonia treated initially using bronchodilators along with antibiotics.

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    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    10 views1 page

    Febrile Seizure

    Uploaded by

    Jaleah Gwyneth Fernandez Edullantes
    This document discusses predisposing and precipitating factors for complex febrile seizures in pediatric patients and the treatment pathway for pediatric community acquired pneumonia. It notes that complex febrile seizures most commonly affect children between 6 months and 3 years old and can be caused by genetic or developmental defects. Pneumonia is usually caused by inhalation or aspiration of pathogens and causes systemic inflammation and lung damage. Both conditions are treated with medications, with febrile seizures treated using medications like midazolam and pneumonia treated initially using bronchodilators along with antibiotics.

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    © All Rights Reserved
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    of 1

    PREDISPOSING FACTORS PRECIPITATING FACTORS

     Age– 6 months old to 3 years old  Environment


     Genetic Developmental Defects  Lifestyle

    Complex Febrile Seizure Pediatric Community Acquired Pneumonia

    Exposure to Pathogen: Inhalation, hematogenous,


    direct , aspiration

    Systemic inflammatory response: Passes to the pharynx , larynx and trachea


    Cytokine Release (TNF, IL-1)
    Microorganisms enters the affects and lung
    parenchyma
    Hyper activate the NMDA Enters to through the
    Receptors present on blood-brain barrier
    neuron
    Damaging of tissue due to release of endotoxins
    Cyclooxygenase Microglia
    -2
    Glutamatergic Neurons releases Local Inflammatory Response:
    glutamate
    Releases pro inflammatory Neutrophils recruited to site of
    Formation of and Anti inflammatory infection by epithelial Cytokine
    Cytokines (IL-1B and IL- release
    Stimulation of glutamatergic Prostaglandin-
    1Ra)
    neurons E2 (PGE2)
    Capillary permeability + Vasodilation

    Cat-ions loads the neuron


    Accumulation of plasma Irritation of contiguous
    dysregulation of the exudate, cell-debris, serous structures and/or
    Increase DEPOLARIZATION of cell glutamatergic and fluid, bacteria and fibrin
    referred pain
    GABAergic circuits
    triggers Action Potential Fluid build up in spaces Irritation of airways and failure
    between alveoli of ciliary clearance to keep up
    Disruption of hypothalamic
    (INTERSTITIAL PATTERN) with fluid build up
    Increased Action Potential thermoregulation
    (Increased level of excitability
    and synchronization of activity)
    Fever ≥38⁰C Fluid build-up in alveoli Congestion

    (LOBAR PATTERN)
    Seizure Activity MEDICATIONS :
    Consolidation
    PARACETAMOL

    Gray Hepatization
    Focal Signs Prolonged > 15
    during seizure minutes Impaired Gas
    Resolution
    Exchange

    MEDICATIONS:
    MIDAZOLAM MEDICATIONS: Sputum

    1. SALBUTAMOL + IPRATROPIUM production


    2. NASATAPP
    3. PULMODUA
    Disease Process MEDICATIONS:
    Signs and Symptoms 1. PHENYLPROPANOLOMINE
    2. AMPICILIN + SULBACTAM
    Medications
    Predisposing and Precipitating
    Factors

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