Professional Documents
Culture Documents
CH 14
CH 14
CH 14
True-False 1-3
Short-Answer 1
Essay
Essay
True-False 4
Short-Answer 2
Essay
Essay
Short-Answer 3,4
Essay
Essay 1
Disorders of Multiple Choice 36-47
Development
True-False 6-9
Short-Answer 5
Essay
Essay 2
Degenerative
Disorders Multiple Choice 48,50,52-58,61,68-73,75-78 49,512,63,64 59,60,62,74
True-False 10-15
Short-Answer 6
Essay
Essay 3,4
Disorders
Multiple 79,80,81,83 82,84
Caused by
Choice
Infectious
True-False 16
Diseases
Short-Answer 7,8
Essay
1) The seizure disorder suffered by Mrs R. in the chapter prologue was treated by
A) administration of tPa.
B) removal of a benign tumor from her brain.
C) administration of antiseizure medication.
D) removal of a malignant tumor from her brain.
E) electrical stimulation of her subthalamus.
Answer: B
Rationale: The seizure disorder suffered by Mrs R. in the chapter prologue was treated by removal of a
benign tumor from her brain.
Diff: 2 Page Ref: 363 Objective: Applied
LO: 14.1 APA 1.1
4) A ________ is a mass of cells without useful function that shows uncontrolled growth.
A) tumor
B) cyst
C) nodule
D) gland
E) polyp
Answer: A
Diff: 1 Page Ref: 363 Objective: Factual
LO: 14.1 APA 1.1
6) A key reason as to why malignant(악성) tumors are deadly is that such tumors
A) can compress liver and pancreatic cells.
B) can grow quickly.
C) are difficult to remove from gut
D) destroy other brain cells through apoptosis.
E) secrete toxic acids
Answer: B
Rationale: A key reason as to why malignant tumors are deadly is that such tumors can grow quickly.
Diff: 2 Page Ref: 363-364 Objective: Conceptual
LO: 14.1 APA 1.1
8) The process through which malignant brain tumors directly damage neurons is
A) the induction of hemorrhage.
B) excessive release of oxygen radicals.
C) compression and infiltration(압축과 침투).
D) the induction of seizure activity.
E) overstimulation of neuron activity.
Answer: C
Rationale: The process through which malignant brain tumors directly damage neurons is compression
and infiltration.
Diff: 2 Page Ref: 364 Objective: Factual
LO: 14.1 APA 1.1
11) Which of the following cells CANNOT give rise to a brain tumor?
A) meningeal cells
B) neurons
C) astrocytes
D) glial cells
E) ependymal cells
Answer: B
Diff: 1 Page Ref: 364 Objective: Factual
LO: 14.1 APA 1.1
12) A tumor of the ________ type was removed from the brain of Mrs. R.
A) malignant
B) glioma
C) angioma
D) blastocyte
E) meningioma
Answer: E
Rationale: A tumor of the meningioma type was removed from the brain of Mrs. R.
Diff: 1 Page Ref: 364 Objective: Applied
LO: 14.1 APA 1.1
17) The key distinction between ________ and ________ seizures relates to whether these involve most
of the brain.
A) simple; complex
B) complex; epileptic
C) generalized; other types of
D) partial; generalized
E) simple; partial
Answer: C
Rationale: The key distinction between generalized and other types of seizures relates to whether these
involve most of the brain.
Diff: 2 Page Ref: 365 Objective: Conceptual
LO: 14.1 APA 3.1
18) The initial phase of a grand mal seizure is termed the ________ and is denoted by ________.
A) clonic phase; relaxation of all muscles
B) tonic phase; rhythmic jerking movements of the body
C) aural phase; perception of music
D) tonic phase; forceful contraction of all muscles
E) aural phase; release of glycine within the spinal cord
Answer: D
Diff: 2 Page Ref: 365 Objective: Factual
LO: 14.1 APA 1.1
19) ________ is the most common of the seizure disorders noted in children.
A) Petit mal disorder
B) Coma disorder
C) Simple partial seizure disorder
D) Absence
E) Status epilepticus
Answer: D
Diff: 1 Page Ref: 366 Objective: Factual
LO: 14.1 APA 1.1
20) ________ is a condition in which a patient shows a series of seizures, but does not regain
consciousness.
A) Petit mal disorder
B) Coma disorder
C) Simple partial seizure disorder
22) An alcoholic who abruptly stops drinking may experience a seizure because
A) of a sudden release from the inhibiting effects of alcohol.
B) this abrupt withdrawal excites GABA receptors.
C) alcohol withdrawal induces hyposensitivity of glutamate receptors.
D) withdrawal leads to brain damage.
E) long-term alcohol abuse causes brain damage.
Answer: A
Diff: 1 Page Ref: 366 Objective: Factual
LO: 14.1 APA 3.1
29) A key treatment for stroke involving weak and malformed blood vessels involves
A) medication to lower blood pressure.
B) administration of antibiotics.
C) administration of demoteplase.
D) brain surgery to seal off(봉인하다) the faulty vessels.
E) medication that speeds up the formation of blood clots.
Answer: D
Rationale: A key treatment for stroke involving weak and malformed blood vessels involves brain
surgery to seal off the faulty vessels.
Diff: 2 Page Ref: 367 Objective: Applied
LO: 14.1 APA 1.1
33) Which of the following represents a therapy for non-hemorrhagic ischemic stroke?
A) drugs that activate GABA receptors
B) drugs that block glutamate receptors
C) drugs that block inflammatory reactions
D) tPa
E) the anticoagulant desmoteplase
Answer: E
Diff: 2 Page Ref: 368 Objective: Factual
LO: 14.1 APA 1.1
34) The impact of ________ within the internal carotid artery is serious because this artery ________.
A) tPa; supplies blood to the gut
B) neurofibrillary tangles; supplies blood to the heart
C) atherosclerotic plaque; supplies blood to the brain
D) tPa; absorbs CSF from the brain
E) atherosclerotic plaque; supplies blood to the gut
Answer: C
Rationale: The impact of atherosclerotic plaque within the internal carotid artery is serious because this
supplies blood to the brain.
Diff: 1 Page Ref: 369 Objective: Conceptual
LO: 14.1 APA 1.1
37) A mother who contracts rubella during her pregnancy may deliver a child that suffers from
A) phenylketonuria.
B) fetal alcohol syndrome.
C) Moebius syndrome.
D) mental retardation.
E) Tay-Sachs syndrome.
Answer: D
Diff: 1 Page Ref: 371 Objective: Factual
LO: 14.1 APA 1.1
48) The brain damage noted in a human who has contracted BSE ("Mad Cow Disease") is caused by a
A) type of protein known as a prion.
B) virus.
C) bacterium.
D) deficiency in blood levels of calcium.
E) kuru virus.
Answer: A
Diff: 1 Page Ref: 373 Objective: Factual
LO: 14.2 APA 1.1
58) Which of the following represents a current therapy for Parkinson's disease?
A) stereotaxically guided destruction of the internal division of the globus pallidus
B) administration of an immune factor against β-amyloid
C) administration of amphetamine or cocaine
D) stereotaxically guided destruction of the internal division of the primary motor cortex
E) administration of haloperidol
Answer: A
Diff: 1 Page Ref: 377 Objective: Factual
LO: 14.4 APA 3.1
60) Administration of ________ may prevent the further development of Parkinson's disease. .
A) L-DOPA
B) deprenyl
C) MPTP
D) L-DOPA
E) hydrogen peroxide
Answer: B
Rationale: Administration of deprenyl may prevent the further development of Parkinson's disease.
Diff: 1 Page Ref: 377 Objective: Applied
62) ________ is a recent treatment 전기자극 for Parkinson's disease that allows patients to suppress their
motor symptoms..
A) Electrical stimulation of the primary motor region
B) Intracranial administration of the drug haloperidol
C) Administration of reserpine into the spinal cord
D) Deep electrical stimulation of the subthalamic region
E) Infusion of GABA into the locus coeruleus
Answer: D
Rationale: Deep electrical stimulation of the subthalamic region is a recent treatment for Parkinson's
disease that allows patients to suppress their motor symptoms.
Diff: 2 Page Ref: 377 Objective: Applied
LO: 14.4 APA 2.1
75) Which of the following is NOT true of amyotrophic lateral sclerosis (ALS)?
A) Most ALS cases are sporadic.
B) ALS is a degenerative disease.
C) The cause of death in ALS is failure of respiration.
D) Spinal cord and cranial motor neurons are destroyed in ALS.
E) ALS is caused by damage to Beta-amyloid in nerve cells. B는 알츠하이머다. 그렇게 외우자.
Answer: E
79) The most common infectious diseases likely to produce neurological damage are ________ and
________.
A) AIDS; polio
B) poliomyelitis; AIDS
C) multiple sclerosis; Alzheimer's disease
D) encephalitis; meningitis
E) rabies; herpes simplex
Answer: D
Diff: 2 Page Ref: 385 Objective: Factual
LO: 14.6 APA 1.1
82) Having a stiff and painful neck is one of the most important symptoms of meningitis because this is
associated with
A) release of excitotoxins by astrocytes.
B) excessive pressure on the carotid artery.
C) painful stretching of inflamed meninges.
D) damage to the motor neurons in the brain and spinal cord.
E) damage to myelin.
Answer: C
Rationale: Having a stiff and painful neck is one of the most important symptoms of meningitis because
this is associated with painful stretching of inflamed meninges.
Diff: 2 Page Ref: 386 Objective: Applied
LO: 14.6 APA 3.1
11) The standard treatment for Parkinson's disease is transplantation of fetal dopamine cells into caudate.
Answer: FALSE 파킨슨 치료는 L-DOPA
Diff: 1 Page Ref: 377
3) Explain the differences between hemorrhagic and obstructive cerebrovascular accidents. What are
common causes of each?
Answer: Hemorrhagic strokes are caused by bleeding within the brain related to a malformed blood vessel
or a high blood pressure. Obstructive cerebrovascular accidents are caused by thrombi or emboli.
Diff: 2 Page Ref: 367-368
4) Explain what causes neuronal death when the blood supply to a region of the brain is interrupted.
Answer: Interruption of blood flow depletes the region’s oxygen and glucose. This leads to release of
glutamate, and cells overstimulated by glutamate die.
Diff: 1 Page Ref: 368
14.4 Essay
2) Describe the symptoms and causes of phenylketonuria and Tay-Sachs disease. How are these
diseases related to one another?
Answer: Each of these diseases is an example of an inherited metabolic disorder. Phenylketonuria is an
inherited lack of an enzyme that results in the buildup in blood of a toxic metabolite of phenylalanine
(resulting in severe mental retardation). During a critical period of postnatal brain development, the PKU
child is placed on a low phenylalanine diet. Tay-Sachs disease is a disease in which the lysosomes are
unable to destroy certain cellular waste products, which accumulate to toxic levels.
Diff: 3 Page Ref: 372-373
3) Describe the etiology and symptoms of Huntington's disease and of Parkinson's disease. How do both
these diseases of the basal ganglia differ from one another?
Answer: Huntington's disease is caused by degeneration of the caudate nucleus and the putamen. It
causes uncontrolled movements. Parkinson's disease is associated with neurodegeneration of the
nigrostrial dopamine system and causes muscle rigidity.
Diff: 2 Page Ref: 378-379
4) Describe the neuroanatomical changes that accompany Down syndrome and Alzheimer's disease. In
what way are these diseases similar to each other? How do they differ from one another?
Answer: Down syndrome is a congenital disorder involving profound mental retardation. The disorder is
induced by the presence of an additional twenty-first chromosome. After age 30, a Down's person will
experience brain atrophy and degeneration (a similarity to that of Alzheimer's disease). Alzheimer's
disease (AD) involves dementia, which first appears as a memory difficulty. AD is associated with severe
degeneration of brain structures such as the hippocampus and neurocortex. Both disorders are
characterized by abnormal intracellular abnormalities.
Diff: 2 Page Ref: 373,379-381