Psoriasis -

Non
contagious
-

•
Chronic
.
Autoimmune Disease
inflammation
.

(
•
skin
microbes
Very Itchy
.

I
Enter the
o silver plaques
epidermis
Teens

⑥
Gama
0%430 Dendrite cell

€cL¥IY7z etnguef epidermal

the microbes .

pin keratinocytes * THE

proliferation * IL -
23 * I L -

17

*
Interferon -

Y Is chronic Inflammation
 • In Psoriasis
Is Immunologic Response
(
↳ Excessive
Inflammation
a
WIES : ↳ Doesn't SHUT OFF

•
Genetic component
↳ chronic skin
damage .

( Run in
families ) y
Environment
•

Tra a
Trigger BLOOD VESSELS DIAL ATES IN

DERMIS

Infection I
-

More Immune cells like

KERATINOCYTES DEFECTS ;

keratin
Neutrophils
l Produce
cotiects
more

*
Thicker
in uppermost
L Retain Nuclei layer ( stratum corneum)

Adhere
( Do not
11
Properly
 I
000
scaly Appearance
§%Ma8
*

SCALES PICKED OFF

( Localized spots )
og

Bleeding
symptoms
•

Gluttatesoriasis
-'
Most common small Red indeii
plaque psoriasis
-

,
•

-
- dual spots
↳ flattened Areas g Elevation limbs
-
on
Trente
dictated Blood
Inflamed e RED starts in child
-

Vessels hood
White silver scales y
-

- -

Sometimes
-

scalp & Tensor

Regions .

by
infection .
 Psoriasis Pustular Psoriasis
Inverse
.
•

Red skin
-

Red lesions
shiny
smooth
=

-
&

klhite elevation g Pas

-

within skin folds .

-
Tender
-
Hands & feet .

•
Erythrocytemic Psoriasis

- fine Red scales .

Psoriatic Arthritis
-

Extremely itchy
e
Painful
l
Inflammation in
Joints
Scales fall in sheet
gf
.
-

Diagnosis :

visual
By
•

Psoriasis
Biopsy confirms
•
Tissue .
 Treatments :
-
clear Plaques
(
• Moisturizers & Emollients -

minimize itchiness .

Tropical & systemic Immunosuppressive

Therapies .

Uv
Phototherapy
•

Tgnduce DNA
damage in
keratinocytes .

• NEW RESEARCH
=

management
( stress

Intervention
piety
(

L
Immuno therapies

Psychological Counselling helps

'

•
.

.
MY