Unit 6: Lymphatic & Immune System

 Identify the structure and function of lymphatic organs (USLO 6.1).

Functions of the lymphatic system:

Lymph Vessels

Lymph Ducts:
Right Lymphatic Duct

Thoracic Duct

Lymph Nodes

Thymus

Bone Marrow

Spleen

Tonsils

MALT
Peyer’s Patch

Appendix
 Identify the mechanisms of the innate (non-specific) defenses (USLO 6.2).

Physical Barriers

Phagocytes & Macrophages

Immune Surveillance

NK Cells

Interferons

Complement

Inflammation
 Fever

 Identify the mechanisms of the adaptive (specific) defenses: Cell Mediated Immunity
(USLO 6.3).

Cells:
Cytotoxic T cells

Helper T cells

Regulatory T cells

Antigen Presentation
Class 1 MHC

Class 2 MHC

Antigen presenting cells (APCs)

Antigen Recognition:
 CD8 cells

CD4 cells

Co-stimulation

Activation of CD8 cells.

Activation of CD4 cells.

 Identify the mechanisms of the adaptive (specific) defenses: Humoral Immunity (USLO
6.4).
B cells

B cell steps
Sensitization

Activation

Differentiation
Antibody classes, structure, and functions:
Structure:
light chain

heavy chain

variable and constant regions

Classes of Antibodies (Immunoglobulins)

IgG

IgM

IgA

IgE

IgD

Antibody Functions

Primary vs secondary immune response

 Differentiate natural and artificial immunity (USLO 6.5).

Natural:
Natural Active Immunity

Natural Passive Immunity

Artificial:
Artificial Active Immunity

Artificial Passive Immunity

 Describe the homeostatic imbalances of the immune system (USLO 6.6).

Autoimmune disorders

Allergies

Lymphomas

Lymphadenopathy

Mononucleosis

HIV/Aids