1. One of the amino acid has two carboxyl groups, which one?

Glutamine / aspartic
acid
2. Which enzyme catalyzes the first reaction of the glycolysis? Hexokinase/
phosphofructokinase (PFK)
3. How many molecules of ATP are consumed in the glycolysis of one molecule of
glucose? two
4. Which is the final product of glycolysis? Pyruvate
5. Which is the final product of the oxidative phase of the pentose phosphate pathway?
ribulose 5-phosphate
6. Which of the following cofactors (or coenzymes) are not involved in the production
of acetyl CoA (activated acetate)? Ubiquinone
7. Which vitamin Is important for vision? Vitamin A
8. Which CoA-ester is used for chain elongation by the human fatty acid synthase?
Malonyl-CoA
9. Which is a corticosteroid hormone? Aldosterone
10. Which protein binds free fatty acid for transport in the blood stream? Albumin
11. Which posttranslational modification is connected to glucagon mediated inactivation
of acetyl-CoA carboxylase (ACC)? Phoshorylation
12. By which process miss-incorporated base can change into a permanent mutation?
Replication
13. Which of the following is not a function of reverse transcriptase?
14. Which of the following types of DNA polymerase does not take part in DNA repair?
DNA Polymerase III
15. The first RNA processing event is ? Capping
16. Amino acids can act as both acids and bases. TRUE
17. In glycine and threonine, the polar group is a hydroxyl (-OH) bounded to aliphatic
hydrocarbon group. TRUE
18. Sucrose, glucose, and maltose are the common disaccharides from dietary
components. FALSE
19. Glycogen is mobilizable store of glucose. TRUE
20. a-amylase is an enzyme secreted by the salivary glands and the pancreas. FALSE
21. in the gluconeogenesis, pyruvate and related three- and four- carbon compounds
are converted to glucose. TRUE
22. The pyruvate dehydrogenase complex consist of three distinct enzymes, namely
pyruvate dehydrogenase (E1), dihydrolipoyl transacetylase (E2), and dihydrolipoyl
dehydrogenase (E3). TRUE
23. Dephosphorylation, the removal of a phosphoryl group from a phosphate ester, is
catalyzed by phosphorylase. TRUE
24. Corticosteroid hormones are derived from cholesterol. TRUE
25. Mitrochondria are central to the initiation of apoptosis. TRUE
26. A kinase transfers a phosphoryl group from a.nucleoside triphosphate such as ATP to
an acceptor molecule. TRUE
27. The presence of one or more fatty acids with cis double bonds interferes with this
tight packing and results in less stable aggregates. TRUE
28. Glycerophospholipids, have two fatty acids attached in ester linkage to the first and
third carbons of glycerol, and a high polar or charged group is attached through a
phosphodiester linkage to the second carbon. TRUE
29. SDS-gel electrophoresis is commonly for separation of lipids. FALSE
30. Paracrine hormones are released into the extracellular space and diffuse to
neighboring target cells. TRUE
31. The polymerase used by the virus to copy its genome forms a covalent bond
between a 5’ phosphate and a 3’ hydroxyl. TRUE
32. Deoxyribonucleotides would be incorporated into the packaged viral genome. FALSE
33. The RNA polymerase can remove only the incorrect bases from the nascent RNA.
FALSE
34. The mutation occurs at a random basis within a genome. TRUE
35. Reverse transcription is an important phenomenon for eukaryotic cells. TRUE
36. Aromatic amino acids tryptophan and tyrosine/phenylalanine contain delocalized
phi electrons and absorb energy strongly near 280nm.
37. mRNA has a Poly A tail at the 3’-end.
38. Some proteins may consist of two or more polypeptide chains. The arrangement of
these polypeptide subunits its called the quaternary structure.
39. The sequences of peptide are read from the N- to the Carboxyl terminus of the
peptide.
40. Protein denaturation results in change in secondary and tertiary structure, not in
primary structure.
41. Lactate acid and Alcohol are the products of the fermentation of pyruvate.
42. Three molecules of NADH are generated in one citric acid cycle
43. The amino acid glutamine transport ammonia from skeletal muscle to the liver.
44. The amino acid aspartate is involved in the generation of arginiosuccinate in the
urea cycle
45. In humans and most other mammals, acetyl- CoA formed in the liver during
oxidation of fatty acids can either enter the citric acid cycle or undergo conversion to
the ‘ketone bodies,” NAPH, FADH2, and GTP for export to other tissues.
46. Melting points of fatty acids are strongly influenced by the length and degree of
unsaturation of the hydrocarbon chain.
47. Elongation of polypeptide chain occurs in three steps called the ribosomal cycle,
which involves initiation, elongation, and termination
48. Telomerase consist of three components, namely teomerase RNA component,
dyskerin, and telomerase reverse transcriptase.
49. List some of the possible combination of alpha helices and beta sheets in
supersecondary structures.
50. How the proton flow drives the ATP synthesis?
51. Explain the sequence of events during synthesis of a fatty acid by human fatty acid
synthase
52. Please describe the mechanism of RNA interference.