DRUG STUDY

Name of the Drug Mechanism of Action Indications Side Effects Nursing Responsibilities
(by system)

Generic name: As does penicillin, the - Uncomplicated Urinary CNS: Dizziness, headache, seizure Before:
CEFIXIME beta-lactam antibiotic Tract Infections. (less than 2%) - Assess underlying condition before therapy
- Advise patient to avoid alcohol and foods that
cefixime inhibits bacterial -Otitis Media. may cause an increase in GI irritation
Brand name: CV: edema.
Suprax cell wall synthesis by -Pharyngitis and Tonsillitis. - Perform a physical examination to establish
disrupting peptidoglycan -Acute Exacerbations of baseline data before beginning therapy to
RESPI: DOB
determine the effectiveness of the therapy and to
Classification: synthesis, resulting in a Chronic Bronchitis. evaluate for the occurrence of any adverse effects
antibiotic, cephalophorin reduction in bacterial cell -Uncomplicated Gonorrhea GI: indigestion, stomach pain; associated with drug therapy.
wall stability and (cervical/urethral) nausea, vomiting
Dosage: During:
bacterial cell lysis. DERMATOLOGIC:
Oral suspension- 100mg / Contraindications - Watch for seizures; notify physician immediately
200mg per 5ml Erythema multiforme, facial edema, if patient develops or increases seizure activity.
-diarrhea from an infection pruritus, skin rash, Stevens- Johnson - Monitor signs of pseudomembranous colitis,
Frequency: with Clostridium difficile Syndrome. including diarrhea, abdominal pain, fever, pus or
one half tablet every 12 hours. bacteria mucus in stools, and other severe or prolonged GI
Genitourinary: problems (nausea, vomiting, heartburn). Notify
-chronic kidney diseases
Acute renal failure, candidiasis, physician or nursing staff immediately of these
Route: Oral
genital pruritus, transient signs.
elevations in BUN or creatinine,
Timing:
vaginitis (less than 2%). After:
Take cefixime before or after
- Instruct patient to notify physician immediately
food. Swallow the tablets
of signs of superinfection, including black, furry
whole with a drink of water. If
overgrowth on tongue, vaginal itching or
you are taking more than one discharge, loose or foul-smelling stools.
dose a day, space your doses - Instruct patient and family/caregivers to report
out evenly throughout the day. other troublesome side effects such as severe or
prolonged skin problems (rash, hives) or GI
problems (nausea, vomiting, diarrhea, cramps).

Reference/Source: https://fadavispt.mhmedical.com/content.aspx?bookid=1873&sectionid=139004577

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