Abstract

One of the most frequently isolated foodborne pathogens is

Salmonella. Considering that it causes 155,000 fatalities
annually and 93.8 million cases of food-borne disease, it is a
significant global public health issue. More than 2500
Salmonella serotypes have been identified to far, and more than
half of these are associated with the most common Salmonella
infection in people, Salmonella enterica subsp. enterica. Invasive
serotypes of Salmonella infections can pose a life-threatening
threat, needing adequate and efficient antibiotic therapy. The
rise of Salmonella serotypes that are multi-drug resistant (MDR)
have a significant impact on the effectiveness of antibiotic
therapy, and an increase in the incidence of MDR strains may
raise the fatality rates associated with Salmonella infections.
According to epidemiological research, MDR Salmonella
serotypes are more virulent than susceptible strains, as
evidenced by the worsening and prolongation of symptoms in
patients who contract MDR strains. It has been suggested to take
preventative steps to stop the spread of the Salmonella illness.
Additional steps like limiting the indiscriminate use of
antibiotics in food animals are crucial, even though maintaining
excellent food hygiene and water sanitation remain the
cornerstones. This article examines the nomenclature,
pathogenesis, clinical symptoms, epidemiology, and antibiotic
resistance of Salmonella in addition to providing an overview of
Salmonella infection.
Conclusion
Around the world, salmonella infection is still a worrisome
public health issue. Salmonella strains can adapt to a variety of
habitats, including those with human, animal, and non-animal
hosts according to their genetic makeup. The difficulty of
getting rid of the bacteria rises as a result. Additionally, the
development of MDR Salmonella strains presents a significant
difficulty in treating infections brought on by these strains. The
restriction of indiscriminate antibiotic use in food animals is
unquestionably one of the most effective preventive approaches
available to curb the spread of the Salmonella infection.
There are two licenced vaccines available for the prevention of
enteric fever, but none are available for the protection against S.
paratyphi and NTS infection. The creation of vaccinations
against all strains of Salmonella could aid afflicted nations
greatly with further study.