flupentixol

A Drug Study Presented to

Lendell Kelly B. Ytac, RN
Faculty, INAHS BSN-Program
Davao Oriental State University

_____________________________________________

In Partial Fulfillment
of the requirements for
NCM 117
Care of Clients with Maladaptive Patterns of Behavior
(Acute and Chronic)

By

Clint S. Ancog
Student Nurse, BSN-3A

March 18, 2022

 Name of Drug Dosage/ Mechanism of Indication Contraindication Side Effects/ Nursing
Frequency/ Action Adverse Effects Responsibilities
Time/ Route
Generic Name: Dosage: The mechanism -Circulatory SIDE ● Observe any
flupentixol of action of collapse, depressed EFFECTS: signs of side
Intramuscular -Flupentixol is
flupentixol is not level of effects and
indicated for ● Constipation
➣ Psychoses, completely consciousness due monitor the
maintenance
Brand Name: Schizophrenia understood. The to any cause (e.g., ● Drowsiness changes noted to
therapy of chronic
Fluanxol antipsychotic alcohol prevent
ADULT: schizophrenic ● Dry mouth
actions are intoxication, complications.
patients whose
For patients mainly thought opiates, ADVERSE
main ● Inform client
Drug Classification: stabilised on oral to arise from barbiturates), EFFECTS:
manifestations do that Flupentixol
Antipsychotic drugs treatment: As cis(Z)- coma; severe
not include -Cardiac can occasionally
flupentixol flupentixol, the depression
excitement, disorders: cause a dry mouth.
decanoate inj: In active requiring
agitation or Palpitation,
Chemical make-up patients who have stereoisomer, electroconvulsive ● Do not give
hyperactivity. tachycardia.
and effect: not received prior acting as an therapy or medicine empty
Flupentixol is an depot antagonist at -It is indicated for hospitalization, and - Eye disorders: stomach as patient
antipsychotic drug of antipsychotics: both dopamine the management states of excitement Abnormal vision, complains of
the thioxanthene Initially, 20 mg is D1 and D2 of depression in or overactivity, accommodation nausea and
group. It exists in given as a test receptors with adult patients who including mania disorder. vomiting.
two geometric dose. After at equal affinities. may, or may not, (for 0.5 or 1 mg tab
isomers, the trans(E) least 1 week also be showing used in depression). -Gastrointestinal
and according to signs of anxiety. Not recommended disorders:
pharmacologically patient response, Pharmacokineti for use in excitable Nausea,
-Flupentixol in vomiting,
active cis(Z) forms. may be followed cs: Flupentixol is or agitated patients.
combination with dyspepsia,
by 20-40 mg metabolized in
melitracen is diarrhea,
every 2-4 weeks the liver via
indicated to sialorrhea.
via deep IM inj. sulfoxidation,
manage
Other patients dealkylation, and -General
may be adequately glucuronidation symptoms of disorders and
maintained on 20- to form anxiety, administration
40 mg every 2-4 pharmacologicall depression, and site conditions:
weeks. Usual y inactive asthenia in adults. Fatigue, asthenia.
dose: Between 50 metabolites.
-Investigations:
mg every 4 weeks Flupentixol
Increased weight.
and 300 mg every decanoate, the
2 weeks. active ingredient -Metabolism and
in the nutrition
Max: 400 mg
intramuscular disorders:
weekly. Dose and
formulation, is Increased
dosing interval
hydrolyzed to appetite.
must be
flupentixol.
individualised and -Musculoskeletal
Fecal excretion
adjusted based on and connective
is more
individual tissue disorders:
predominant
symptoms and Myalgia.
than renal
response. Max inj
excretion. -Nervous system
volume
recommendations Pharmacodyna disorders:
may vary mics: Dizziness,
depending on the Flupentixol is an drowsiness,
concentration antipsychotic headache, hyper-
used (refer to agent with or hypokinesia,
detailed product anxiolytic and tremor.
guideline). mild sedative -Psychiatric
actions. It exerts disorders:
ELDERLY: As
weak Depression,
flupentixol
anticholinergic insomnia,
decanoate inj:
and adrenergic nervousness,
Initial dose may
effects. It agitation,
require to be
reduced to 1/4 or possesses disturbance in
1/2 of the usual antiemetic attention.
starting dose. actions. As
-Renal and
Flupentixol
ORAL urinary
works by
disorders:
➣ Depression antagonizing
Micturition
dopamine
ADULT: Cases disorder.
actions, it can
with or without cause -Reproductive
anxiety: As 0.5 or extrapyramidal
system and
1 mg flupentixol effects, mostly at breast disorders:
dihydrochloride doses greater Decreased libido.
tab: Initially, 1 mg than 10 mg.
daily as a single -Respiratory,
dose in the thoracic and
morning. After 1 mediastinal
week, dosage may disorders:
be increased to 2 Dyspnea.
mg daily given in
-Skin and
2 divided doses
subcutaneous
according to
tissue disorders:
patient response.
Hyperhidrosis,
Max: 3 mg daily.
pruritus.
Withdraw
treatment if no
effect has been
observed within 1
week of taking the
max dose.
ELDERLY: As
0.5 or 1 mg
flupentixol
dihydrochloride
tab: Initially, 0.5
mg daily as a
single dose in the
morning. After 1
week, dosage may
be increased to 1
mg once daily
according to
patient response.
Max: 1.5 mg daily
given in 2 divided
doses.
ORAL
➣ Psychoses,
Schizophrenia
ADULT: As 3 mg
flupentixol
dihydrochloride
tab: 3-9 mg bid,
adjusted
according to
patient response.
Max: 18 mg
daily.
ELDERLY: As 3
mg flupentixol
dihydrochloride
 tab: Initial dose
may require to be
reduced to 1/4 or
1/2 of the usual
starting dose.
➣ Special Patient
Group
Oral/IM:
For
Schizophrenia;
Psychoses:
Debilitated
patients: As 3 mg
flupentixol
dihydrochloride
tab/as flupentixol
decanoate inj:
Initial dose may
require to be
reduced to 1/4 or
1/2 of the usual
starting dose.

References:

Schull, P. (2013). McGraw-Hill Nurse’s Drug Handbook Seventh Edition. McGraw-Hill Companies, Inc.

Skidmore-Roth, L. (2021). Mosby’s 2021 Nursing Drug Reference, 3251 Riverport Lane St. Louis, Missouri 63043
Wishart DS, Knox C, Guo AC, Shrivastava S, Hassanali M, Stothard P, Chang Z, Woolsey J. Drugbank: a comprehensive resource for
in silico drug discovery and exploration. Nucleic Acids Res. 2006 Jan 1;34 (Database issue):D668-72. 16381955.