PATHOPHYSIOLOGY

(IDEAL)

smoking, emotional stress Reduction in blood flow Reduction in mucosal resitance

PEPTIC ULCER DISEASE

Reduce generation power of
epithelial cell

Increased action of acid-pepsin

Reduced mitotic activity

H.pylori infaction & NSAIDs

Steroid therapy
 PATHOPHYSIOLOGY
(ACTUAL)

Signs and symptoms

 Body weakness
 Dizziness
 Vomiting

Factors:  BURNING STOMACH

PAIN
 Age  BLOATING OR
 Gender BELCHING
 Lifestyle (smoking)
 Stress
PEPTIC ULCER DISEASE
 High, multiple use of
aspirin & NSAIDs