Scribd Logo
Upload

Welcome to Scribd!

  • Pka Chart

    Uploaded by

    Himansu Bisoi
    32 views1 page
    This document provides an approximate pKa chart of common functional groups, listing their pKa values. Key pKa values include carbonyl groups at -7, alcohols or ethers from -2 to -3, carboxylic acids at 4-5, ammonium ions at 9-10, phenols at 10, thiols at 10, alcohols at 16-18, water at 15.7, amides at 18, alpha protons of ketones/aldehydes at 20, alpha protons of esters at 25, terminal alkynes and amines at 25 and 38-40 respectively. Aromatic and benzylic groups have higher pKa values of 43 and 41,

    Original Description:

    Original Title

    pka-chart

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    This document provides an approximate pKa chart of common functional groups, listing their pKa values. Key pKa values include carbonyl groups at -7, alcohols or ethers from -2 to -3, carboxylic acids at 4-5, ammonium ions at 9-10, phenols at 10, thiols at 10, alcohols at 16-18, water at 15.7, amides at 18, alpha protons of ketones/aldehydes at 20, alpha protons of esters at 25, terminal alkynes and amines at 25 and 38-40 respectively. Aromatic and benzylic groups have higher pKa values of 43 and 41,

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    32 views1 page

    Pka Chart

    Uploaded by

    Himansu Bisoi
    This document provides an approximate pKa chart of common functional groups, listing their pKa values. Key pKa values include carbonyl groups at -7, alcohols or ethers from -2 to -3, carboxylic acids at 4-5, ammonium ions at 9-10, phenols at 10, thiols at 10, alcohols at 16-18, water at 15.7, amides at 18, alpha protons of ketones/aldehydes at 20, alpha protons of esters at 25, terminal alkynes and amines at 25 and 38-40 respectively. Aromatic and benzylic groups have higher pKa values of 43 and 41,

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    of 1

    Approximate 

    pKa chart of the functional groups:  values to know 
     
    1.  Protonated carbonyl  pKa = ‐7                                                   Other important pKa’s 
    2. Protonated alcohol or ether   pKa = ‐2 to ‐3        H2 = 35  
    3. Carboxylic acid   pKa = 4‐5 
    4. Ammonium ion   pKa = 9‐10 
    5. Phenol  pKa = 10 
    6. Thiol  pKa = 10 
    7. Alcohol   pKa = 16‐18 
    8. Water  pKa = 15.7 
    9. Amide   pKa = 18 
    10. Alpha proton of ketone/aldehyde  pKa = 20 
    11.   Alpha proton of ester   pKa = 25 
    12. Terminal alkyne    pKa = 25 
    13. Amine   pKa = 38‐40 
    14.  Aromatic:  Aryl 43, benzylic 41 
    15. Alkene:  vinyl 45‐50; allylic 43 
    16. Alkane  pKa = above 50 
     
    Examples: 
    -7
    -2 to -3 -2 to -3
    OH O
    H
    O OH2 4-5

    OH

    H2
    OH SH 10
    N
    10
    9-10
    16-18
    OH
    O O

    18 20
    NH2 CH3

    H
    O 25 38-40
    H H N
    25
    O
    43
    41 45-50 above 50
    H
    H (vinyl)
    H (aryl) H
    (allylic)
    (benzylic)
    H
    43  
     

    You might also like