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“Where working hard is a habit”

IIT ASHRAM
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CLASS : 11 DATE: 19-01-22

CLASSROOM WORKSHEET

SYLLABUS : Chemical Co-ordination and Integration

Max. Marks : 180 Marking Scheme : + 4 for correct & (–1) for incorrect Time : 60 min.

INSTRUCTIONS : This Daily Practice Problem Sheet contains 45 MCQs. For each question only one option is correct.
Darken the correct circle/ bubble in the Response Grid provided on each page.

1. Which hormone possesses anti-insulin effect? (a) electrophoresis


(a) Cortisol (b) Calcitonin (b) electroencephalogram
(c) Oxytocin (d) Aldosterone (c) fractionation
2. Which of the following is both exocrine and endocrine gland ? (d) radioimmunoassay
(a) Liver (b) Pancreas 6. Testosterone is produced by
(c) Thyroid (d) Adrenal (a) sertoli cells (b) leydig’s cells
3. Chemically hormones are (c) oxyntic cells (d) pituitary gland
(a) biogenic amines only 7. Which one of the following pairs correctly matches a
(b) proteins, steroids and biogenic amines hormone with a disease resulting from its deficiency?
(c) proteins only (a) Luteinizing - Failure of ovulation
(d) steroids only (b) Insulin - Diabetes insipidus
4. The blood calcium level is lowered by the deficiency of (c) Thyroxine - Tetany
(a) parathormone (d) Parathyroid - Diabetes mellitus
(b) thyroxine 8. Which one of the following is not a second messenger in
(c) both calcitonin and parathormone hormone action ?
(d) calcitonin (a) Calcium (b) Sodium
5. The technique used for estimation of minute amounts of (c) cAMP (d) cGMP
hormones and drugs is called
RESPONSE
9. Which of the following statements regarding glucagon is (c) seminiferous tubules and provide nutrition to germ cells
false? (d) pancreas and secrete cholecystokinin
(a) It is secreted by -cells islets of Langerhans. 14. The phase of menstrual cycle in humans that lasts for 7-8
(b) It acts antagonistically to insulin. days, is
(c) It decreases blood sugar level. (a) follicular phase (b) ovulatory phase
(d) The gland responsible for its secretion is heterocrine (c) luteal phase (d) menstruation
gland.
10. Which one of the following statements is correct? 15. Blood glucose level in man is regulated by:
(a) Neurons regulate endocrine activity, but not vice versa. (a) insulin
(b) Endocrine glands regulate neural activity and nervous (b) adrenaline
system regulates endocrine glands. (c) glucagon and insulin
(c) Neither hormones control neural activity nor the (d) All of the above
neurons control endocrine activity. 16. Which of the following glands grows to the maximum size at
(d) Endocrine glands regulate neural activity but not vice puberty and then diminishes gradually?
versa. (a) Thymus (b) Pituitary
11. Match the source gland with respective hormone as well as (c) Thyroid (d) Adrenal
the function correctly. 17. Hypoglycemic hormone is
(a) Insulin (b) Glucagon
Source gland Hormone Function (c) Thyroxine (d) Calcitonin
(a) Anterior Oxytocin Contraction of 18. Which of the following diseases is caused by the under
pituitary uterus muscles secretion of cortisol?
(a) Anaemia
during child
(b) Addison’s disease
birth
(c) Hyperglycemia
(b) Posterior Vasopressin Stimulates (d) Mental illness or retardation
pituitary reabsorption 19. Glycogen is converted to glucose by
of water in the (a) Insulin
distal tubules (b) Glucagon
(c) Galactose
in the nephron
(d) Both glucagons and insulin
(c) Corpus Estrogen Supports 20. A decrease in the level of oestrogen and progesterone
luteum pregnancy causes
(d) Thyroid Thyroxine Regulates (a) Growth and dilation of myometrium
blood calcium (b) Growth of endometrium
level (c) Constriction of uterine blood vessels leading to
sloughing of endometrium or uterine epithelium
12. Which of the following is incorrect? (d) Release of ovum from the ovary.
(a) Iodine is needed for thyroxine formation. 21. Which of the following is a minerelocorticoid?
(b) Calcium regulates the excitibility of nerve fibres. (a) Calciferol (b) Progesterone
(c) Potassium plays an important role in the regulation of (c) Adrenalin (d) Aldosterone
acid base balance in cell. 22. Which hormone interacts with membrane bound receptor
(d) Phosphorus helps to maintain the osmotic pressure of and does not normally enter the target cell ?
the body fluids. (a) Follicle stimulating hormone
13. Sertoli cells are found in (b) Estrogen
(a) ovaries and secrete progesterone (c) Thyroxin
(b) adrenal cortex and secrete adrenaline (d) Cortisol
23. The 24 hour (diurnal) rhythm of our body such as the sleep- 32. Hormones generally cause a response in a cell by
wake cycle is regulated by the hormone (a) interacting directly with the cell’s DNA.
(a) Adrenaline (b) Melatonin (b) binding with a receptor and stimulating protein
(c) Calcitonin (d) Prolactin production.
24. Steroid hormones transmit their information by (c) changing the polarity of the cell membrane and causing
(a) stimulating the receptors present on cell membrance a cascade of events within the cell.
(b) entering into the cell and modifying cellular contents (d) halting all other cellular activity except the required
(c) entering into the cell and modifying nuclear organization response
(d) the help of an intracellular second messenger 33. Hormones are produced at a particular centralized site and
25. Increase in bleeding time and delay in blood coagulation transported throughout the organism by means of
is due to the deficiency of which hormone? (a) a series of synapses
(a) Adrenaline (b) Noradrenaline (b) an integrated neural pathway system.
(c) Parathormone (d) Thyroxine (c) cellular communication
26. Estrogen and testosterone are steroid hormones, and (d) an internal transport system
most likely bind to 34. Injections of a hormone are sometimes given to strengthen
(a) membrane ion channels contractions of the uterus during childbirth. What hormone
might this be?
(b) enzyme-linked membrane reseptors
(a) adrenocorticotropic hormone (ACTH)
(c) G-protein coupled membrane receptors
(b) thyroxine
(d) cytoplasmic receptors
(c) oxytocin (d) insulin
27. The only unicellular exocrine glands in our body are
35. The graph below illustrates the changes in blood sugar
(a) Sweat glands
concentration after a healthy man has drunk a glucose
(b) Mucus secreting goblet cells
solution.
(c) Mammary glands
(d) Sebaceous glands
28. Steroid-based hormones are able to act inside the cell. This
is possible because
(a) there are no receptors for hormones on the cell surface.
(b) hormones must interact with the nucleus to have an
effect.
(c) proteins carry them into the cell.
(d) steroid-based hormones are hydrophobic molecules
that can pass through the cell membrane.
29. Every time you eat a cookie or candy bar, your blood sugar Which one of the following graphs would apply to a diabetic
increases. This triggers an increase in the hormone man in similar circumstances ?
(a) thyroxine. (b) epinephrine.
(c) glucagon. (d) insulin.
30. Target cells (a) (b)
(a) react specifically to a chemical messenger.
(b) have receptors for chemical messengers
(c) secrete hormones
(d) Both a and b
31. Researchers have found increased levels of hormones from
the _____ in the blood of students preparing for final exams.
These hormones are produced in response to stress. (c) (d)
(a) thyroid gland (b) pineal gland
(c) posterior pituitary (d) adrenal glands
36. A paracrine hormone is 41. Through negative feedback, a hormone may shut off the
(a) a local hormone that acts on the cell that releases it. secretion of an anterior pituitary hormone by :
(b) always acting on a wide variety of target tissues. (a) stimulating the release of a (hypothalamic) releasing
hormone
(c) a local hormone produced at one site but active at a
different site in the body. (b) inhibiting the release of a (hypothalamic) inhibiting
hormone
(d) none of the above
(c) inhibiting the release of a (hypothalamic) releasing
37. “Upregulation” of hormone receptors refers to hormone
(a) increase in hormone receptor numbers with low (d) all of the preceding.
hormone levels. 42. ANF is a peptide hormone and is secrected from
(b) increase in hormone receptor numbers with high (a) Gastrointestinal tract (b) Kidney
neurotransmitter levels (c) Post. Pituitary (d) None of these
(c) increase in hormone levels produced by increase in 43. Steroid hormones –
hormone receptor numbers (a) have only cell surface receptors
(d) decrease in hormone levels produced by decrease in (b) are lipophobic
hormone receptor numbers (c) act through altering the activity of proteins in the target
38. In an experiment, researchers removed the ____ of young cell
mice, and as a result, these mice were able to accept organ (d) are produced by only adrenal cortex.
transplants without rejection. 44. The hormones that initiate ejection of milk, stimulates milk
(a) pineal glands (b) thymus glands production and growth of ovarian follicles are respectively
(c) thyroid glands (d) parathyroid glands known as
(a) PRL, OT and LH (b) OT, PRL and FSH
39. Which of the following is a common second messenger
substance in hormone action ? (c) LH, PRL and FSH (d) PRH, OT and LH
45. A pregnant female deliver a baby who suffers from stunted
(a) Thyroid hormone (b) ADH
growth, mental retardation/low intelligence quotient and
(c) Cyclic AMP (d) Epinephrine abnormal skin. This is the result of :
40. Which of the following glands is considered the “master” (a) Low secretion of growth hormone
endocrine gland in vertebrates ? (b) Cancer of the thyroid gland
(a) Adrenal glands (b) Thyroid gland (c) Over secretion of pars distalis
(c) Hypothalamus (d) Pituitary gland (d) Deficiency of iodine in diet

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