The nasal cavities are divided into regions including the olfactory region and respiratory region. The olfactory region contains olfactory receptor cells that detect odors and supporting cells. The respiratory region contains structures like the nasal vestibule, nasal cavities, and paranasal sinuses lined with respiratory epithelium. The nasal cavities communicate with the external environment and nasopharynx. Various cell types maintain the nasal cavities and detect odors.
The nasal cavities are divided into regions including the olfactory region and respiratory region. The olfactory region contains olfactory receptor cells that detect odors and supporting cells. The respiratory region contains structures like the nasal vestibule, nasal cavities, and paranasal sinuses lined with respiratory epithelium. The nasal cavities communicate with the external environment and nasopharynx. Various cell types maintain the nasal cavities and detect odors.
The nasal cavities are divided into regions including the olfactory region and respiratory region. The olfactory region contains olfactory receptor cells that detect odors and supporting cells. The respiratory region contains structures like the nasal vestibule, nasal cavities, and paranasal sinuses lined with respiratory epithelium. The nasal cavities communicate with the external environment and nasopharynx. Various cell types maintain the nasal cavities and detect odors.
The nasal cavities are divided into regions including the olfactory region and respiratory region. The olfactory region contains olfactory receptor cells that detect odors and supporting cells. The respiratory region contains structures like the nasal vestibule, nasal cavities, and paranasal sinuses lined with respiratory epithelium. The nasal cavities communicate with the external environment and nasopharynx. Various cell types maintain the nasal cavities and detect odors.
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shelf-like, bony nasal cavities projections divide each nasal cavity into separate air conchae chambers / turbinates and play a dual role filtration of inspired air through the process conchae / turbinates of turbulent precipitation general name for cells that has short, conchae / turbinates blunt microvilli basal cells but has secretory granules; brush cells enteroendocrine stem cells from which cells of thethe APUD other cellsystem Small granule cells (Kulchitsky cells) types arisevascular network that includes has a rich, basal cells a complex set of capillary contains mucous loops glands whose secretion LAMINA PROPRIA supplements that of the goblet cells variable extent, the contiguous lateral and medial LAMINA PROPRIA nasal in color walls due to the pigment in the olfactory OLFACTORY REGION OF THE NASAL CAVITY epithelium and olfactory glands OLFACTORY REGION OF THE NASAL CAVITY Contiguous Contains, blood and lymphatic vessels,▪unmyelinated with the periosteum of th Lamina propria olfactory Apical domain nerves,hasmyelinated a dendriticnerves, processolfactory ▪that Lamina glands propria projects above the vesicle and extend radially in a plane parallel to vesicle epithelial surface as a knoblike structure olfactory called the epithelial surface; dura andnonmotile arachnoidor may have matters, limited▪ OLFACTORY surrounded mobility by pia mater, RECEPTOR CELLS enters formedthe by olfactory bulb of the brain ▪ OLFACTORY RECEPTOR CELLS the collections of axons from olfactory receptor cells olfactory nerve (cranial nerve I) Lifespan autonomic of nervous about 1 month system, they appear OLFACTORY to be the onlyRECEPTOR CELLS neurons readily replaced during postnatal OLFACTORY life RECEPTOR CELLS columnar cells that are similar to neuro S UPPORTING provide mechanical and metabolic support to the olfactory OR SUSTENTACULAR CELLS receptor cells SUPPORTING OR SUSTENTACULAR CELLS synthesize and secrete odorant-bindinSUPPORTING OR SUSTENTACULAR CELLS most Nucleinumerous occupy a more cells inapical the olfactory position inSUPPORTING the epithelium ORthan SUSTENTACULAR CELLS do those ofmicrovilli numerous the otheroncell types their SUPPORTING apical surface, OR SUSTENTACULAR CELLS and abundant mitochondria SUPPORTING OR SUSTENTACULAR CELLS Numerous SER and limited RER ▪ SUPPORTING OR SUSTENTACULAR CELLS Have Adhering junctions are found between▪these lipofuscin granules SUPPORTING cells andORtheSUSTENTACULAR CELLS olfactory receptor cells ▪ SUPPORTING OR SUSTENTACULAR CELLS No gap stem andfrom cells tightwhich junctions ▪ SUPPORTING new olfactory receptor cells andOR SUSTENTACULAR CELLS supporting cells differentiate basal cells small, ensheatherounded cellsportion the first locatedofclose to t basalreceptor the olfactory cells cell axon basal cells same cell type that occurs in the respi brush cells large, surface basal blunt microvilli at their is in synaptic apicalwith contact s brush nervecells fibers that penetrate the basal lamina brush Involved in transduction of general sensory stimulation of cells the mucosa vesicles near the apical cell membrane,brush and acells well-defined Golgi their proteinaceous secretions via ducts ontocells apparatus brush the olfactory surface serves as a trap and solvent serous secretion OLFACTORYfor GLANDS (BOWMAN’S GLANDS) odoriferous air-filled spacessubstances in the bones of the walls OLFACTORY of the nasalGLANDS (BOWMAN’S GLANDS) cavity PARANASAL SINUSES lined Ethmoid,by respiratory epithelium frontal, sphenoid, and maxillary PARANASAL (named SINUSES after the bonewith communicate where thethey arecavities nasal located) PARANASAL via narrow SINUSES openings onto the respiratory mucosaparanasal sinuses Mucosal surface has Mucus produced numerous in the goblet sinuses is swept paranasal into the sinuses nasal cavities connects the nasal and oral cavities to the larynxsinuses by coordinated ciliary movements paranasal and esophagus pharynx passageway for air and food pharynx acts as a resonating chamber for spee pharynx posterior connect the to the nasal and oral cavitiespharynx nasopharynx to each middle nodules ear at the junction auditoryand between the superior (Eustachian) tubes posterior passageway for air between the oropharynx and tonsil walls of the pharynx pharyngeal trachea elastic cartilage (epiglottis and the vocal larynx processes of the arytenoid cartilages) larynx serves as the organ for producing sou larynx two folds lateral of mucosa boundaries ofthat project into the opening vocal of the foldsthe rima larynx, glottidis vocal folds Skeletal muscle; contained within eachvocalis muscle Insert on cartilages of the larynx extrinsic laryngeal muscles originate in extralaryngeal structure extrinsic laryngeal muscles move the larynx during deglutition ( extrinsic laryngeal muscles Elongated recess above the vocal co ventricle Pair do notof mucosal have thefolds immediately intrinsic muscular abov ▪ ventricular investment folds of the true(false cords) vocal cords = do Inflammation andnot modulate swelling in phonation of the larynx▪ ventricular folds (false cords) caused by viruses and other microbial agents ▪ Acute hoarseness or, in more severe cases, the total loss of voice, laryngitis coughing, caused by and difficulty prolonged with swallowing exposure ▪ Acute and of irritating breathing laryngitis agents such as tobacco short, smoke,airdust, flexible, tubeand/or about polluted 2.5 cm inair Chronic diameter laryngitis and about conduit10for cmairlong trachea inspired and its wall assists in conditioning air trachea extends from the larynx to about the mtrachea divides lumen staysinto the open two main (primary) because brtrachea of the of the arrangement series ofpseudostratified ciliated, cartilaginous rings epithelium and trachea an elastic, fiber-rich lamina propria mucosa composed of a slightly denser connective tissue than the lamina propria SUBMUCOSA composed of C-shaped hyaline cartilagCARTILAGINOUS LAYER unique preventfeature collapseofofthe thetrachea tracheal lumenCARTILAGINOUS particularly LAYER during expiration composed of connective tissue that binds CARTILAGINOUS the trachea LAYER to adjacent structures most numerous and extend through the full thickness adventitia of the hair-like short, epithelium profiles projecting fromCILIATED the apicalCELLS surface below the cilia is a dark line formed by the aggregated CILIATED CELLS ciliary serves basal as an bodies important protective mechanism CILIATEDfor CELLS removing small inhaled similar particlesto in appearance from the lungs intestinal “mucociliary goblet cells and are escalator thus often referred to by the same interspersed among the ciliated cells and also extend name mucous cells through the full thickness number increases of the epithelium during chronic mucous irritation cells of the air passages Respiratory representatives of the general classcells mucous of enteroendocrine usually occur singly cells of the in the gut and trachea andgut SMALL arederivatives GRANULE CELLS (KULCHITSKY CELLS) sparsely dispersed microscope among without thespecial other cell types SMALL techniques such as GRANULE silver CELLS (KULCHITSKY CELLS) staining, which reacts with the granules SMALL GRANULE CELLS (KULCHITSKY CELLS) the secretion reserve is catecholamine cell population that maintains SMALL individualGRANULE cell CELLS (KULCHITSKY CELLS) replacement prominent because their nuclei form abasal in the epithelium row in cells close proximity to the basal lamina Diffuse lymphatic tissue and lymphatic nodules basal cells characteristically Contains the larger extend into this distributing layersubmucosa vessels and lymphatics C-shaped; sometimes anastomose w/ adjacent submucosa cartilages arrangement provides flexibility to theCARTILAGINOUS tracheal pipe LAYER and also maintains lies peripheral patency to the cartilage of the ringslumenCARTILAGINOUS and trachealis LAYER muscle Binds trachea to adjacent structures in the neck and adventitia mediastinum supply the tracheal wall and larger lymphatics adventitia that drain the wall bronchopulmonary segments; left lungadventitia has _ and the right lung has segmental _ bronchus 8, 10 and the lung parenchyma discontinuous cartilage plates it supplies that becomebronchopulmonary smaller as segment bronchial diameter diminishes with that of adjacent structures (pulmonary artery and Cartilage layer lung smallerparenchyma) units of structure that Adventitia make up the pulmonary lobules Pulmonary acini smallest functional unit of pulmonary consists of a single respiratory bronchiole respiratory and the bronchiolar alveoli unit that it supplies nonciliated cells with rounded or dome-shaped respiratory bronchiolar unit apical surface projection preventing luminal adhesion should the Clara wallcells of the airway collapse on itself during first part of the bronchial tree that allows gasexpiration Clara cells exchange Respiratory bronchioles involved Have a narrow diameter and are lined Respiratory in both air conduction and g by cuboidal bronchioles site of gas exchange; actual sites of gasRespiratory epithelium exchange bronchioles between increases the the air and the surface area blood availabale for alveoli lung exchange alveoli terminal surrounded air spaces of the of by a network respiratory capillariesalveoli bringing blood closer to the elongated inhaled airways thatairhave insidealmost the alveolus noalveoli walls, only alveoli, as their peripheral boundary Alveolar ducts spaces surrounded by clusters of alveoAlveolar sacs surrounding May occur atalveoli open into of the termination these the spAlveolar ducts but may sacs occur anywhere along the length of the Alveolar ducts sacs surrounds thin and separates connective tissue layer thethat alveoli f alveolar contains bloodseptum or septal wall capillaries alveolar septum or septal wall decreases the alveolar surface tension and actively participates in the clearance of foreignsurfactant materials