DRUG INDICATION DOSE

50-100mg/8h chewed at start of

ACARBOSE DM type II
each meal
ACETAZOLAMIDE Diuretic 250-500mg/12h PO
200mg/5 times a day or 400mg/3
ACYCLOVIR Herpes gladiatorum
times a day for 7-10d
ALBENDAZOLE Anthelmentic 400mg PO once

ALENDRONATE Osteoporosis 10mg/24h PO

ALPRAZOLAM Anxiety 0.25-0.5mg/8h PO

AMIKACIN Antibiotic 7.5mg/kg/12h IV
AMITRYPTYLINE Post-herpetic neuralgia 25-100mg/24h
IBS (Diarrhoea predominant; pain &
AMITRYPTYLINE 10-25mg PO nocte
bloating)
AMITRYPTYLINE Painful diabetic neuropathy 25-75mg HS

AMLODIPINE Angina pectoris 5-10mg/24h

10mg/kg/d, followed by 5mg/kg/d

AMODIAQUINE Malaria
for 2d

AMOXICILLIN Antibiotic 250-500mg/8h PO

250-500mg/6h PO
AMPICILLIN Antibiotic
500mg-1g/6h IM/IV

6 dose
regiment:4X(20+120mg)/12h for 3d
ARTEMETHER+LUMEFA with food
Falciparum Malaria
NTRIEN 4 dose
regiment:4x(20+120mg)/12h on 1st
day then /24h on 2nd & 3rd day.

100mg/kg/d PO in divided doses

ASPIRIN Rheumatic fever (max 8g/d) for 2d, then 70mg/kg/d
for 6wk
Prevention of severe flushes in Rx
ASPIRIN 300mg 1/2h pre-dose
with Nicotinic acid
ASPIRIN Analgesia 300-900mg/6h PO
ASPIRIN Antiplatelets 75-150mg/24h PO

ATENOLOL Hypertension 50mg/24h PO

ATENOLOL Angina pectoris 50-100mg/24h PO

ATENOLOL MI 5mg IV
ATOVAQUONE+PROGU 1tab/24h PO starting 1d before
Malaria prophylaxis
ANIL travel, till 7d after return
ATOVAQUONE+PROGU
Falciparum Malaria 4tab/24h for 3d with food
ANIL

2mg/10min IV till full atropinization

ATROPINE Organophosphates poisoning
(dry skin, pulse>70, dilated pupils)
ATROPINE Arrhythmia 0.6-1.2mg IV
AZITHROMYCIN Typhoid fever 500mg/24h PO for 7d
500mg/24h PO for 3d
AZITHROMYCIN Pneumonia (community acquired)
500mg/24h, then 250mg/24h for 3d

5-30mg/8h PO. Increase dose

BACLOFEN Muscle relaxant
gradually (max 100mg/d)
BECLOMETASONE Asthma 100mcg/12h inh
BENDROFLUMETHIAZID
Hypertension 2.5mg/24h PO
E
BENZYLPENICILLIN 0.6-1.2g IM stat then Penicillin V
Rheumatic fever
(PENICILLIN G) 250mg/6h PO
BENZYLPENICILLIN
Meningitis 2.4g/4-6h slowly IV
(PENICILLIN G)
BENZYLPENICILLIN
Antibiotic 300-600mg/6h IV
(PENICILLIN G)

BICARBONATE (HCO3-) (24 - restult) x wt in kg x 0.3 /2

BLOOD TRANSFUSION
10ml/kg body wt
(Paeds)

BROMAZEPAM 1.5-3mg/12h PO for 8-12wk

BUDESONIDE Asthma 100-250mcg/12h inh
BUSCOPAN 10-20mg/8h PO
CAPTOPRIL Hypertension 12.5-50mg/12h PO
CAPTOPRIL Hypertensive urgency/emergency 12.5-25mg PO

15-40mg/24h PO for 4wk, gradually

reduceing according to TFTs every
CARBIMAZOLE Hyperthyroidism
1-2mo. Maintain on 15mg/24hr for
12-18mo then withdraw.

CEFACLOR Antibiotic 250mg/8h PO

CEFADROXIL Antibiotic 500mg-1g/12h PO
CEFALEXIN Antibiotic 500mg/8h PO
CEFAMANDOLE Antibiotic 500mg-2g/4-8h IM/IV
CEFEPIME Antibiotic 1-3g/12h IVI
CEFIXIME Antibiotic 200mg/12-24h PO
CEFOTAXIME Antibiotic 1-2g/12h IV/IM
CEFOTAXIME Gonorrhoea 500mg stat
2g stat deep IM with Probenecid 1g
CEFOXITIN Gonorrhoea
PO
CEFOXITIN Antibiotic 1-2g/6-8h IV/IM
CEFPIROME Antibiotic 1-2g/12h IV over 5min
250-500mg/6h PO
CEFRADINE Antibiotic 500mg-1g/12h PO
500mg-2g/6h IM/IV
CEFTAZIDIME UTI 500mg-1g/12h IV/IM
CEFTAZIDIME Antibiotic 1-2g/8h IV/IM
CEFTRIAXONE Antibiotic 1-4g/24h IM/IV
250-500mg/12h PO
CEFUROXIME Antibiotic
750mg-1.5g/8h IV/IM
5-10mg/24h PO
CETIRIZINE Antihistamine
5mg/12h PO
12.5mg/kg/6h PO/IV
CHLORAMPHENICOL Antibiotic 25mg/kg/6h may be used in
septicemia/meningitis
CHLOROQUINE Malaria prophylaxis 300mg/wk PO

600mg PO, 300mg 6h later, then

CHLOROQUINE Benign Malaria
300mg/24h for 2d

4mg/6h PO
CHLORPHENIRAMINE Antihistamine
10-20mg IM/IV
CIMETIDINE Antacid 400mg/6-12h PO
CIPROFLOXACIN Acute diarrhoea 500mg/12h PO for 5-7d
CIPROFLOXACIN Typhoid fever 500mg/12h PO for 7-14d

CIPROFLOXACIN Px of SBP 750mg/wk

250mg/12h PO for 3d
CIPROFLOXACIN UTI
For upper UTI, continue Rx for 14d

250-750mg/12h PO
CIPROFLOXACIN Antibiotic 200-400mg/12h IVI over >1/2 to
>1h
CITALOPRAM Depression 10-20mg/24h PO
CLARITHROMYCIN H. pylori (as Triple therapy) 500mg/12h PO for 1wk
CLARITHROMYCIN Antibiotic 250-500mg/12h PO for 7-14d
CLEMASTINE Antihistamine 1mg/12h PO
150-300mg/6h PO
CLINDAMYCIN Antibiotic 0.2-0.9g/8h/ IV/IM (by IVI only, if
>600mg)
CLOPIDOGREL Antiplatelets 75mg/24h PO
Topical 1% cream; continue for 14d
CLOTRIMAZOLE Ring worm
after healing

375-625mg/8h PO
CO-AMOXICLAV Antibiotic
1g/12h PO

CO-TRIMOXAZOLE
(SUFAMETHOXAZOLE
Antibiotic 960mg-1.44g/12h PO/IVI
400MG+
TRIMETHOPRIM 80MG)
CODEINE Diarrhoea 30mg/6h PO/IM
CODEINE PHOSPHATE Analgesia 30-60mg/4h PO/IM

CODEINE PHOSPHATE Diarrhoea 30mg/6h PO

CYCLIZINE Antiemesis 50mg/8h PO/IM/IV
DALTEPARIN DVT prophylaxis 2500-5000U/24h SC
DALTEPARIN Unstable angina 120U/kg/12h SC for 2-8d
DALTEPARIN DVT/PE Rx 200U/kg/d SC
DESLORATIDINE Antihistamine 5mg/24h PO
10-20mcg/12-24h intranasally
DESMOPRESSIN Diabetes insipidus (smallest dose that controls
polyuria)
50mg/8h PO
DICLOFENAC Analgesia 75mg/24h deep IM (for max 2d,
continue PO if necessary)
500mcg stat PO, repeated after 12h,
DIGOXIN AF then 125mcg(if elderly)-375mcg/d
PO
DIHYDROCODEINE 30mg/4-6h
Analgesia
TARTARATE 50mg/4-6h IM/SC
DOMPERIDONE Antiemesis 10-20mg/6h PO

75mg PO nocte (elderly: 50mg),

DOSULEPIN Anxiety, depression, insomnia
increase to 2-3tab if necessary
DOXYCYCLINE Acute diarrhoea 100mg/12h
DOXYCYCLINE Acne Vulgaris/Rosacea 100mg/12h
DOXYCYCLINE Pneumonia (community acquired) 100mg/12h PO

DOXYCYCLINE Malaria prophylaxis 100mg/24h PO

200mg PO on 1st day then
DOXYCYCLINE Antibiotic
100mg/24h
40-80mg/8h PO
DROTAVERINE Antispasmodic
20-40mg/8h IM/SC
ENOXAPARIN Unstable angina 1mg/kg/12h SC for 2-8d
ENOXAPARIN DVT prophylaxis 20-40mg/24h SC

ENOXAPARIN DVT/PE Rx 1.5mg/kg/24h SC until warfarinized

ERYTHROMYCIN Tetanus prophylaxis after injury 500mg/6h for 7d

250-500mg/6h PO for 7-14d

ERYTHROMYCIN Antibiotic
6.25-12.5mg/kg/6h IVI
ERYTHROPOIETIN Anemia of renal failure 50-150U/kg twice weekly
ESOMEPRAZOLE Antacid 20-40mg/24h PO
ETHAMBUTOL Tuberculosis 15-20mg/kg
20mg/12h HS
FAMOTIDINE
20-40mg/24h HS

FERROUS SULPHATE Iron-deficiency anaemia 325mg/12h PO (=60mg Fe)

120-180mg/24h PO
FEXOFENADINE Antihistamine
60mg/12h PO
250-500mg/6h PO/IM; take 1/2h
FLUCLOXACILLIN
Antibiotic before food
(CLOXACILLIN)
0.5-2g/6h IV
50mcg every 2nd day to 0.15mg
FLUDROCORTISONE Addison's disease
daily. Adjust on clinical grounds

4mgl/kg for 1st 10kg, 2ml/kg for 2nd

FLUID Maintenance
10kg, 1ml/kg for the rest

200mcg IV, then 100mcg/min if req,

FLUMAZENIL Benzodiazepine overdose
upto 1mg max
FLUOXETINE Depression 20-80mg/24h PO
FLUTICASONE Asthma 50-200mcg/12h inh
FRESH FROZEN
10-15ml/kg body wt
PLASMA (FFP)
FUROSEMIDE Hypertensive urgency/emergency 10-80mg IV

FUROSEMIDE Diuretic 40mg/24h PO

500mg/8h PO
FUSIDIC ACID Antibiotic
500mg/8h IV over 6h
GABAPENTIIN Painful diabetic neuropathy 300-600mg/8h
300mg/24h PO, increase slowly to
GABAPENTIIN Post-herpetic neuralgia
300mg/12h

200mg/24h PO for 3d
GATIFLOXACIN UTI
For upper UTI, continue Rx for 14d

0.7-1.7mg/kg/8h IV
Typical once daily dose: 160mg/d
GENTAMYCIN Antibiotic
Single stat dose for simple
infections: 5mg/kg

GLIBENCLAMIDE DM type II 2.5-15mg/24h PO at breakfast

GLICLAZIDE DM type II 40-160mg/d PO as a single dose

GLIMEPIRIDE DM type II 1-4mg/d, max 8mg/d
0.5-1mg SC/IV/IM (+- a repeat
GLUCAGON Hypoglycemia
after 20min)
25-50g VI via a large vein with a
GLUCOSE Hypoglycemia 0.9% saline flush to prevent
phlebitis
GRISEOFULVIN Ring worm 0.5-1g/24h
HALOPERIDOL Rheumatic fever (Chorea) 0.5mg/8h PO
2-5mg IM/IV initially, then every 4-
HALOPERIDOL Tranquilizer
8h till response, max 18mg in total

HEPARIN
DVT prophylaxis 5000U/12h SC
UNFRACTIONATED
HYDROCHLOROTHIAZI
Diuretic 12.5mg/24h PO
DE
20mg in morning, 10mg at bed time
HYDROCORTISONE Addison's disease
PO
 1mg/2d (alt days) IM for 2wk (or, if
HYDROXYCOBALAMIN CNS signs, until improvement stops;
Pernicious anaemia
(B12) then 1mg/2mo (every 2mo) IM for
life
IBUPROFEN Analgesia 400mg/6h PO
IMIPENEM Antibiotic 250-500mg/6h IVI
IMIPRAMINE Depression 75mg/24h PO
IMIPRAMINE Chronic pain syndrome 50mg nocte
Urinary incontinence (Detrusor
IMIPRAMINE 50mg PO at night
instability)
IPRATROPIUM
Asthma 20-80mcg/6h inh
BROMIDE
ISONIAZID (INH) Tuberculosis 5mg/kg, max 300mg
ISOSORBIDE
Angina prophylaxis 10-30mg/12h PO
MONONITRATE
ISOTRETINOIN Acne Vulgaris/Rosacea 0.5-1mg/kg/d
ITOPRIDE Antiemesis 50mg/8h PO 30min before meal
ITRACONAZOLE Ring worm 100-200mg/24h PO for 7d
IVERMECTIN Resistant scabies/lice 200mcg/kg PO
15-30ml/8h, adjust the dose
LACTULOSE Hepatic encephalopathy gradually until the bowels are
moving twice daily
LANSOPRAZOLE Antacid 15-30mg/24h PO for 4-8wk
LEVAMISOLE Anthelmentic 150mg PO single dose
LEVOCETIRIZINE Antihistamine 5mg/24h PO
LEVOFLOXACIN Acute diarrhoea 500mg/24h PO for 5-7d
LEVOFLOXACIN RTI 500mg/24h PO

250mg/24h PO for 3d
LEVOFLOXACIN UTI
For upper UTI, continue Rx for 14d

600mg/12h PO/IV for 10-14d (max

LINEZOLID Antibiotic
duration: 28d)
LISINOPRIL Hypertension 2.5-20mg/24h PO
4mg stat then 2mg after each loose
LOPERAMIDE Diarrhoea
stool
LORATIDINE Antihistamine 10mg/24h PO
LOSARTAN Hypertension 50-100mg/24h PO
LOSARTAN Heart failure 25mg/24h PO
MEBENDAZOLE Ascaris, hookworms 100mg/12h PO for 3d
100mg PO stat; repeat at 2wk if
MEBENDAZOLE Enterobius vermicularis
>2y
MEBEVERINE Antispasmodic 135/8h PO AC
MEFLOQUINE Malaria prophylaxis 250mg/wk PO
MEROPENEM Antibiotic 0.5-1g/8h IVI
500mg-1g/8h PO pc (to reduce GI
METFORMIN DM type II
upset)
METHYLPHENIDATE Narcolepsy 5-20mg/8h PO
METOCLOPRAMIDE Antiemesis 10mg/8h PO/IM/IV
Initially 5mg/d in the morning, then
METOLAZONE HTN
5mg on alt day
METOLAZONE Edema 5-10mg/d, max 80mg/d
500mg/12h PO for 7d
METRONIDAZOLE Giardiasis
2g/24h PO for 3d
METRONIDAZOLE Acne Rosacea 0.75%/12h or 1%/24h

400mg/8h IV for 10d; repeat at 2wk

METRONIDAZOLE Amoebic liver abscess
as needed
 400mg/8h PO
METRONIDAZOLE Antibiotic
500mg/8h IVI for <=7d

800mg/8h PO for 5d, then

METRONIDAZOLE Amoebic dysentry Diloxanide furoate 500mg/8h PO for
10d to destroy gut cysts
25-100mg/8h at the start of each
MIGLITOL DM type II
meal
MINOCYCLIN Acne Vulgaris/Rosacea 50-100mg/12h
MINOCYCLIN Antibiotic 100mg/12h PO
MONTELUKAST NA Asthma 10mg PO nocte
MORPHINE Analgesia 5-10mg/4h PO/IM/SC
MOXIFLOXACIN Pneumonia 400mg OD for 10d

0.4-2mg/2min IV untill breathing

NALOXONE Opiate overdose
adequate, max 10mg

NATEGLINIDE DM type II 60-120mg/8h 15min ac

NICORANDIL Angina pectoris 10-30mg/12h PO
NIFEDIPINE Chillblains (Perniosis) 20-60mg/24h PO
60mg/4h PO for 3wk
NIMODIPINE Subarachnoid hemorrhage
1mg/h IVI
NITROFURANTOIN UTI 50mg/6h PO with food

NITROGLYCERINE Hypertensive urgency/emergency 0.25-0.5mcg/kg/min

NIZATIDINE 150mg/12h PO
NORFLOXACIN Px of SBP 400mg/d

400mg/12h PO for 3d
NORFLOXACIN UTI
For upper UTI, continue Rx for 14d

NORFLOXACIN Acute diarrhoea 400mg/12h PO for 5-7d

OCTREOTIDE Variceal bleeding 50mcg IV, then 50mcg/hr inf

OFLOXACIN Acute diarrhoea 400mg/12h PO for 5-7d

OMEPRAZOLE Antacid 20-40mg/24h PO
8mg/8h PO
ONDANSETRON Antiemesis
4mg IM/IV
ORPHENADRINE 100mg/12h PO
OXYTETRACYCLINE Antibiotic 250-500mg/6h PO
PANTOPRAZOLE Antacid 20-40mg/24h PO
PARACETAMOL Analgesia 500mg-1g/4-6h PO
PAROXETINE Depression 20mg/24h PO

Child: 250mg/12h PO for 10d

PENICILLIN V Pharyngotonsillitis
Adult: 500mg/8-12h PO for 10d

PETHIDINE Analgesia 50-100mg/4h PO/IM/SC

PHENIRAMINE Antihistamine 12.5-25mg/12h PO

PHENOXYMETHYLPENIC 250-500mg/6h PO; take 1/2h before

Antibiotic
ILLIN (PENICILLIN V) food

PHENOXYMETHYLPENIC Rheumatic fever secondary

250mg/12 PO
ILLIN (PENICILLIN V) prophylaxis

PICOSULPHATE NA Laxative 10mg PO nocte

PIOGLITAZONE DM type II 15-45mg/24h
PIPEMIDIC ACID UTI 400mg PO BD for 7-10d
PIPERAZINE Enterobius vermicularis 0.3ml/kg/24h for 7d

PIROXICAM 40mg/24h PO for 2d then 20mg/24h

PIZOTIFEN Migraine prophylaxis 0.5mg/8h PO

POTASSIUM (K+) Hypokalemia (4.5 - result) x wt in kg x 0.4

1-2g IV slow diluted in at least 10ml

PRALIDOXIME Organophosphates poisoning
water, then 250-500mg/hr inf
50mg/24h PO for 5d +/- 10mg/day
PREDNISOLONE Bell's palsy
for 5 more days
15mg/24h for 14-21d after
PRIMAQUINE P ovale/vivax Malaria
Chloroquine
50mg/24 PO. Increase to 50mg/12h
PROCATEROL Asthma
if necessary
PROCATEROL Asthma 50mg/12-24h PO
5-10mg/8h PO
PROCHLORPERAZINE Antiemesis
12.5mg/6h IM
PROGUANIL Malaria prophylaxis 200mg/24h PO
PROPRANOLOL Prevention of variceal bleeding 80-160mg/d
PROPRANOLOL Hyperthyroidism 40mg/6h PO
40mg/24h, increase to 40mg/8h if
PROPRANOLOL Anxiety
necessary
PROPRANOLOL Benign Essential tremor (BET) 40-80mg/8-12h PO
PROPRANOLOL HTN 160-320mg/d
PYRAZINAMIDE Tuberculosis 20-25mg/kg, max 2g
PYRIDOXINE Sideroblastic anemia 10mg/24h PO
600mg/8h PO for 5-7d, together
with/followed by
Fansidar 3tab single dose,
QUININE Falciparum Malaria Tetracycline 250mg/6h for 7d,
Doxycycline 100mg/12-24h for 7d,
or
Clindamycin 300mg/6h for 7d
20mg/kg IV over 4h then 10mg/kg
QUININE Malaria
IV over 8-12h
RANITIDINE Antacid 150mg/12h PO
REPAGLINIDE DM type II 0.5-4mg/8h 15min ac
RIFAMPICIN Tuberculosis 10mg/kg, max 600mg

RIFAMPICIN(UK)/
Antibiotic 450-600mg/24h PO before breakfast
RIFAMPIN(US)

ROSIGLITAZONE DM type II 4-8mg/24h

ROXITRHROMYCIN Antibiotic 150mg/12h PO

SALBUTAMOL Asthma 100-200mcg/6h inh

50-100mcg/12h inh
SALMETEROL Asthma
2-4mg/8h PO
10mg/24h PO; Increase to 15mg if
SIBUTRAMINE Obesity
wt loss < 2k after 4wk
SILYMARIN Liver disease 10ml/12h for 4-6wk, then 10ml/24h

SIMVASTATIN Hyperlipidemia 10-40mg PO at night

300mg/24h PO, then 200mg/24h or
SPARFLOXACIN Antibiotic
100mg/12h
SPIRONOLACTONE Diuretic 25mg/24h PO
STREMPTOMYCIN Tuberculosis 15mg/kg, max 1g/dose
SUCRALFATE 1g/6h PO
Rheumatic fever secondary
SULFADIAZINE 1g/d PO (0.5g if <30kg)
prophylaxis
SUMATRIPTAN Migraine 50mg PO
TAMSULOSIN BPH 0.4mg/24h
TEMAZEPAM Hypnosis 10-20mg PO at night
TERBINAFINE Ring worm 250mg/24h PO for 4wk
 2mg/6h IV until bleeding stops,
TERLIPRESSIN Variceal bleeding
then 1mg/6h for a further 24h

250-500mg/6h PO before food

TETRACYCLINE Antibiotic
500mg-1g/12h IVI

TETRACYCLINE Acne Vulgaris/Rosacea 250-500mg/12h

THALIDOMIDE Myelofibrosis 100mg/48h (on alternate days)

100mcg/24h PO. Review at 12wk

and adjust dose by clinical state and
TSH
If elderly: start with 25mcg/24h and
THYROXINE Hypothyroidism
increase every 4wk
If IHD: give Propranolol 40mg/6h
PO and start with 25mcg/24h of
Thyroxine

TIBOLONE Symptoms of estrogen deficiency 2.5mg/24h PO

TINIDAZOLE Giardiasis 2g PO once

TINZAPARIN DVT prophylaxis 3500-4500U/24h SC
TINZAPARIN DVT/PE Rx 175U/kg/24h SC until warfarinized

TIZANIDINE 2-4mg/8h PO
TOBRAMYCIN Antibiotic 200mg/12 PO
TOLBUTAMIDE DM type II 0.5-1.5g/d in 2-3 doses
TOLTERODINE Urge incontinence 2mg/12h PO
Urinary incontinence (Detrusor
TOLTERODINE 1-2mg/12h PO
instability)
TRAMADOL Analgesia 50-100mg/4-6h PO/IM/SC
250-750mg/8h PO
TRANEXAMIC ACID
500mg-1g/8h IV

200mg/12h PO for 3d
TRIMETHOPRIM UTI
For upper UTI, continue Rx for 14d

TRIMETHOPRIM-
Px of SBP 160/800mg/d
SULPHAMETHOXAZOLE

TRIMETHOPRIM-
Acute diarrhoea 160/800mg/12h
SULPHAMETHOXAZOLE

TRIMETHOPRIM-
1 tab/12h PO for 3d
SULPHAMETHOXAZOLE UTI
For upper UTI, continue Rx for 14d
(160MG+400MG)
TULOBUTEROL Asthma 1mg/12h PO
125mg/6h PO
VANCOMYCIN Antibiotic 500mg/6h IVI over 1h
1g/12h IVI over 100min
Vitamin K deficiency / Warfarin 10-20mg/24h PO
VITAMIN K
overdosage 10mg IV/IM/SC
ZAFIRLUKAST Asthma 20mg/12h PO
ZOLMITRIPTAN Migraine 2.5mg PO
 COMMENTS

1/2h before breakfast with plain

water only. Supplemental Ca & Vit D
if dietary intake is inadequate.

The antidepressant dose is 75-

150mg.

2.5mg/6h in small & fragile geriartic

patients and those with hepatic
insufficiency

Amoxcillin is better absorbed PO

than Ampicillin. For IV therapy, use
Ampicillin.

Higher doses provide little additional

benefit

250-500mcg/12h inh???
200-800mcg/12h inh ???

No dose change in renal failure

4th generation cephalosporin

Avoid IM if dose >1g

Avoid in pregnancy & lactation

If P ovale/vivax then Primaquine

15mg/24h for 14-21d after
Chloroquine. Test for G6PD first.

Alt: Azithromycin 500mg PO for 7d

For prophylaxis, use once daily &

re-evaluate the need for continued
therapy after 6-12mo.
If intractable, try Itraconazole,
Terbinafine or Griseofulvin

To minimize potential
gastrointestinal intolerance and to
optimize absorption of drug,
administer at the start of a meal.

CI: G6PD deficiency

Used in Penicillin allergy

Continue for 3-6mo after restoration
of normal hematologic values to
replenish stores

1ml=100mcg
May precipitate fits

For prophylaxis, use once daily &

re-evaluate the need for continued
therapy after 6-12mo.

Spectrum-wide but poor against

Streps & anaerobes, so use with a
Penicillin and/or Metronidazole

Avoid prolonged use, with

furosemide, in pregnancy and
Myasthenia
Long-acting

Medium acting
Avoid in pregnancy & lactation

On empty stomach

For prophylaxis, use once daily &

re-evaluate the need for continued
therapy after 6-12mo.

May cause reversible Pancytopenia

if Rx >2wks

If aged <2y, try Piperazine

AC - Ante Cibum
Avoid in pregnancy

Alt: Tinidazole

Aspirate if no improvement within

72h of starting Metronidazole.
Give Diloxanide post-metronidazole.
Drug of choice against anaerobes,
Entamoeba, Giardia.
Use PO in Pseudomembranous
collitis

Spectrum >Tetracycline

1amp=0.4mg
SE: symptoms of opiate withdrawal
(diaarhea, cramps), give Lomotil
2/6h PO

Start within 3d

Inj Isoket 1mg in 100ml Pladex 3-

6drops/min

For prophylaxis, use once daily &

re-evaluate the need for continued
therapy after 6-12mo.

1amp=50mcg
Octreotide is the synthetic form of
Somatostatin

Penicillin V is less active than

Penicilln G. It is used as prophylaxis
or to complete an IV course.

Carditis - for 10y or until 25y old

No carditis - for 5y or until 18y old
Alt: sulfadiazine 1g/d (0.5g if
<30kg)
If presentation is within 6d of onset

Test for G6PD first

Alt: Aretemether+Lumefantrine OR
Atovaquone+Proguanil

Mycobacteria
Prophylaxis in meningitis contacts

Frequency may be increased to 6

times if needed.
Relesease the vasoconstrictor
Vasopressin, in amounts sufficient
to reduce portal hypertension
without producing systemic effects

Avoid if <12yr old, in pregnancy

Absorption decreases with iron,
milk, antacids

t1/2 of Thyroxin is 7d

Alt: Metronidazole

Short-acting
Alt: Oxtbutynin

For prophylaxis, use once daily &

re-evaluate the need for continued
therapy after 6-12mo.

For prophylaxis, use once daily &

re-evaluate the need for continued
therapy after 6-12mo.

PO in Pseudomembranous collitis if
Metronidazole is contraindicated