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Anatomy and Physiology
Anatomy and Physiology
1 / 12
USMLE Step 1 Physiology and anatomy
Study online at https://quizlet.com/_1h752u
2 / 12
USMLE Step 1 Physiology and anatomy
Study online at https://quizlet.com/_1h752u
Apocrine glands are found around armpits & the nipples and the
groin regions of the body. They are initially odorless, but then bac-
difference between apocrine and eccrine and merocrine gland
teria on body makes it smelly. Eccrine is the same as merocrine
gland. They are all over the body and secrete sodium and chloride
Holocrine, involves death of the cell. The secretory cell is re-
leased and as it breaks apart, the contents of the cell become
the secretory product. Involved sebaceous glands [oils]. paracrine
glands produce chemical signals that are sent to neighboring cells
difference between holocrine and paracrine gland through a process of diffusion. Paracrine glands are sometimes
classified as a subset of exocrine glands. Exocrine glands are
glands which produce secretions destined for the surface of an or-
gan, as opposed to endocrine glands, which secrete compounds
into the bloodstream.
menotropin and HCG mimic what Follicle stimulating hormone and Lutenizing hormone
supraoptic nuclei produce ADH and paraventricular nuclei pro-
What produces ADH and Oxytocin
duces oxytocin
Glut 2 is liver and pancreatic cells. Glut 4 is adipocyte and mus-
cular cell. glut 1 and glut 3 is everywhere.
what are the four types of Glut receptors and their location
3 / 12
USMLE Step 1 Physiology and anatomy
Study online at https://quizlet.com/_1h752u
catalyzes iodine oxidation to have thyroglobulin iodination. Not
what is the role of thyroid peroxidase thyroglobulin synthesis. also remember thionamide blocks this
process
perchlorate prevents uptake of iodine to thryoid tissues. thion-
what does perchlorate, thionamides, and beta blockers do with
amide prevents thyroglobulin iodination. and beta blockers prevent
the thryoid hormone pathway
thryoid uptake in peripheral tissue.
increased FSH, though later LH is also increased. Don't think
it is decreased estrogen... since your peripheral tissue makes
what biochemical change marks menopause
estrogen. But this is confusing since how come FSH would not
remain inhibited then...
Secretin by S endocrine cells in the duodenum, which stimulates
what increases bicarbonate secretion in the GI tract
pancreatic exocrine secretion of bicarbonate.
primary amenorrhea, streak gonad, widely spaced nipples, ele-
what are some tale tell sign of turner syndrome
vated gonadotrophins [LH and FSH], but normal endometrium
when ions are elevated and decreased in pancreas secretion from increased HCO3- and decrease chloride. sort of like the chloride
secretin shift phenomena.
parietal cells in the body and fundus of the stomach. Gastrin is a
peptide hormone that stimulates secretion of gastric acid (HCl)
what secretes intrinsic factor, and what other factor is also re-
by the parietal cells of the stomach and aids in gastric motility.
leased from this organ.
It is released by G cells in the pyloric antrum of the stomach,
duodenum, and the pancreas.
cephalic [cholinergic and vagal mechanism], gastric [gastrin me-
what are the three phases of acid secretion from stomach
diated], and intestinal
ileum and colon release peptide YY, which binds to enterochro-
what causes the decrease in gastric acid production maffin like cells. This prevents gastrin stimulated histamine re-
lease
what is absorbed in the duodenum, what is absorbed in the duodenum is just lipid digestion. lipid absorption, which includes
jejunum fat soluble vitamins is at the jejunum
ileum absorbs bile and vitamin B12, colon is where fluid and
what is absorbed in the ileum, what is absorbed in the colon
electrolytes are reabsorbed
cholecystokinin, hormone responsible for gallbladder contraction.
what can cause subcostal pain after fatty meal
Made in duodenum and jejunum in response to fatty acids
in response to low PH, it inhibits growth hormones and thyroid
what does somatostatin do. what therapeutic purpose can it serve stimulating hormone, glucagon. As an octreotide, it can be used to
treat symptoms of cancer, like carcinoid syndrome or acromegaly.
it inhibits active transport. specifically, it inhibits the parietal cells
what kind of transport is inhibited by omeprazole
by blocking the H+/ K+ ATPase. Hence you can't make HCL
how many calories is yielded from one gram of protein, and one
4 cal for one gram of protein, and 9 cal for one gram of fat
gram of fat
endometrium has coiled gland filled with carbohydrate rich mu- secretory phase of menstrual cycle occurs from day 15 through
cus, edematous stroma, and torturous spinal arteries. Which time day 28. Progesterone level is still elevated, but the lutenizing
point is this hormone has come back down from its peak.
in the menstrual and early proliferative phase it is a thin, brightly
echogenic stripe comprising of the basal layer.
in the late proliferative phase it develops a trilaminar appearance:
outer echogenic basal layer, middle hypoechoic functional layer,
and an inner echogenic stripe at the central interface.
phases of endometrium and the appearance
in the secretory phase it is at its thickest and becomes uniformly
echogenic, as the functional layer becomes edematous and isoe-
choic to the basal layer.
The postmenopausal endometrium should be smooth and homo-
geneous.
supposedly it is at part 4. but it is voltage gated K+ channels, so
you'd think most would be open at the peak
4 / 12
USMLE Step 1 Physiology and anatomy
Study online at https://quizlet.com/_1h752u
Right gives rises to the posterior descending artery and Left gives
rise to left anterior descending [anterior interventricular branch],
and left circumflex
what are the two main coronary arteries, and what vessels do they
give rise to
8 / 12
USMLE Step 1 Physiology and anatomy
Study online at https://quizlet.com/_1h752u
what is the position of the heart. what gets hit at the right sternal
border. what gets hit at the left sternal border.
what are the parts of the duodenum first, second, third, which is close to the superior mesenteric artery
passage of a large gallstone through a cholecystenteric fistula.
It ultimately causes an obstruction at the ileocecal valve. So the
obstruction will be at the ileum. interesting.
9 / 12
USMLE Step 1 Physiology and anatomy
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cervical ligament contains the uterine artery and needs to be
ligated during radical hysterectomy
Spleen can be ruptured by the 9th, 10th, or 11th rib. kidney by the
where does the spleen lie, how about the kidney based on rib
12th rib.
caused by persistent processus vaginalis and failure of internal
what causes the indirect [lateral to inferior epigastric vessels],
inguinal ring to close; weakness of transversalis fascia; protrusion
direct, and femoral hernias
of femoral ring, inferior to the inguinal ligament
accumulation of fluids around a testicle, and is fairly common. It is
often caused by fluid secreted from a remnant piece of peritoneum
wrapped around the testicle, called the tunica vaginalis
The organ of corti, this is what gets damages from excessive loud
noise. There is stereocilia which is efferent [inner hair cell].
palate elevation involves which nerves CN IX, and X. Sort of like gag reflex
skin, superficial cervical fascia (including subcut fact and platys-
ma), investing and pretracheal layers of the deep cervical fascia,
and cricothryoid membrane
10 / 12
USMLE Step 1 Physiology and anatomy
Study online at https://quizlet.com/_1h752u
ternal branch [cricothryoid muscle] and internal branch [sensory
innervation above the vocal cords]
cerumen impaction, cholesteatoma, otosclerosis, tympani mem-
what are causes of conductive hearing loss
brane rupture
what are causes of sensorineural hearing loss [will have unaffect- meniere's disease, acoustic neuroma, ototoxic drugs (aminogly-
ed rinne test] cosides), presbycusis
helicotrema [at the tip] and oval window is where high frequency
where in the cochlea is the low and high frequency heard?
heard. The most stiff region.
what drains the ipsilateral side of the face and arm brachiocephalic vein
arises from the C1-3. It innervaes the sternohyoid, sternothryoid,
and omohyoid muscle of the anterior neck. Penetrating traum to
neck above the cricoid cartilage can injure this nerve
11 / 12
USMLE Step 1 Physiology and anatomy
Study online at https://quizlet.com/_1h752u
what regions of the buttock will hit the superior gluteal nerve, how
Superomedial; superomedial, inferomedial, inferolateral
about the sciatic nerve
prepatellar bursa
So I would say it is the right knee, and that the medial part really
is the medial part [the one where it seems like there is more curve
at the side]
what kind of fracture is common with elderly people with osteo- the femoral neck is most common, and the artery affected is
porosis who fall, and what artery is affected medial femoral circumflex
the deep brachial artery. does not show on the image, but it does
branch from the axillary artery
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