Radiotherapy

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Radiotherapy one of major

cancer treatment modality


Haydar Hamza Alabedi

3ed lecture
Radiotherapy for CNS tumors
Gliomas AlmostalwaysrequireradiotherapythatisAdjuvanttosurgery
sinceGliomasareaggressivetumors
HGG, GBM High GradeGlioma Glioblastoma
some types of LGG
Ependymoma Radioresistant surgery str
tereotactic
radiotherapy STR, WHO III , Posterior fossa WHO II
Primitive cell tumors
rade 485
rvivalrate
Medulloblastoma, PNET, pinoblastoma
children CNS lymphoma Chemosradiotherapy
rgerytradio
therapy Metastatic disease, relapsed glioma
WBRT or SRS
Benin brain tumors
Acoustic neuroma
Craniopharyngioma
pressingthe
nerve
Trigeminal neuralgia Couldbe causedby atumoriom
Terminal pain
Aswholebrainirradiation
s performedformore
severecasesbeinga
moreaggressiveapproach
tcouldcausemore
cognitivedysfunction
comparedwithSRS
Craniospinal
radiation
to prevent
ceding
851
arrival
rate MB
Medulloblastoma
Hippocampus sparing preservingcognitivefunction
Radiotherapy for Head and Neck cancers
Nasopharyngeal cancer radicalRadiotherapy In RadiotherapyoftheHAN
Oropharngeal cancer weshouldsparetheparotid
Radiotherapy
Hp g
gland to reducetheintidence
Oral cancer alsoinCacervix radiosensitive of Xerostomiathatgreatly
reducesqualityoflifeimparin
Laryngeal cancer TotalLaryngectomy swallowing
Butnowthereis
Parotid cancer a rolefor radiotherapy
NPC
Critical
organs
0
Ca larynx 3D
Vs IMRT
Intensity
modulated
Radiotherapy

SparingtheISAinpatients
Wi IschemicHeartdisease
Lung cancer
morethan
Adenocarcinoma
of thelung
Small cell lung cancer Radiotherapy see is sensitive
to radiotherapy
CCRT for limited stage disease But its anaggressivedisease

Non small cell lung cancer


CCRT for stage III spreadto mediastinal LN chemoradiotherapy
SBRT for I & II
Mesothelioma as adjuvant treatment
LADarteryisthemostsensitive toinjury

Advanced
lung cancer
due to Highmobility
GIT I Allexceptthe small intestinea colon T
Esophageal cancer
radical CCRT
Neoadjuvant
adjuvant
Gastric cancer Adjuvanttherapy to LN
Adjuvant
Pancreatic cancer
Radical
adjuvant
Rectal cancer , neo adjuvant CCRT
most rectal cancersare Adenocarcinomas
I
Anal cancer, Radical treatment WhileAnalcancersare 901 squamous all
carcinomas
hostly
squamouscellcarcinoma
respondingwellto radiation
Rectal cancer
Hematology WBCisthemostradiosensitivecell

Lymphomas Radiotherapy aftersuccessfulchemo


HL
stage I, II and bulky disease
NHL, low grade lymphoma and DLBCL

Multiple myeloma Forpaincontrolonly


Plasmacytoma Singlelesion not systemic radical radiotherapy
Leukemia
CNS involvement
7
testicular involvement Radiotherapy
g
Permanentinfertility
Gyneoncology
Ca Cx Sensitive to radiation
Adjuvant CCRT
Radical RT
EBRT and brachytherapy

Endometrial cancer Surgery s radioadjuvanttherapy


adjuvant RT
EBRT or Brachytherapy or both
Geneto urinary cancer
Bladder cancer
radical CCRT insteadofcystectomy veryimp forquality
of Life
adjuvant to pelvic LN in case ofcystectomy
Prostate cancer
radical RT main
modality
Adjuvant
Testicular cancer
Adjuvant RT or chemotherapy
Sara aortic
LN

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