Fourth Quarter, S.Y.

_________
Week No.: Date: Grade and
Section:
Topic: Mitosis: What Body Process Turns One Cell into Two
Learning Competency Code: The leaners should be able to compare mitosis and meiosis, and their
role in the cell-division cycle. (S8LT-IVd- 16)
21ST Century Learning Skills: Communication, Information Literacy, ICT Skill, Responsibility
Objective/s:
Given the necessary materials, the students should be able to:
1. name the parts of the cell that have important roles in cell division;
2. sequence the stages of the cell cycle; and
3. summarize the events in each of the four stages of mitosis.
Science Process Skills Included:
Observing, Comparing and Contrasting, Classifying, Formulating hypothesis
Learni Time
Materi
ng Activity Fram
als
Guide e
Identification: Identify the word being described by each of the following
statements.

1. It contains the genetic material. Clue: The answer has 7 letters.

2. It is the membrane that covers the cell. Clue: The answer has 12 letters.
3. It is the fluid that fills the cell. Clue: The answer has 9 letters.
4. It is the cylindrical structure composed of microtubules. Clue: The answer
5
Engag has 9 letters. PPT
minut
e slide
es

Answer:
1 Nucleus
2. Cell membrane
3. Cytoplasm
4. Centriole

What body process turns one cell into two?

Picture 5
Engag
of an minut
e Answer:
animal. es
Mitosis is the process that turns one cell into two.

Interactive: Stages of Mitosis

15
See what happens to a cell. Interact
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ive
es
Answer to the interactive will be updated soon.
Explor
e
Makebl
ock
Manipulative: Beautiful Mitosis 15
Neuron
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Creativ
Make a creative presentation of the stages of mitosis. es
e Lab
Kit

SUBJECT (TEACHER’S NAME): 1

 Unplugged Activity: Food

Create a demonstration. Cut an apple into half. Explain that the apple has seed,
skin and other parts. When you cut the apple into half, ask the students: After
15
cutting the apple into half, do they still have the same parts?
minut
es
You can now start discussing how mitosis occur.

Guide Questions:

Interactive: Stages of Mitosis

1. How many cells was/were there before mitosis happened?

- There is only one cell before mitosis happen.

2. Do/ Does the cell/s have a nucleus, genetic materials, and centrioles?
- Yes the cell have nucleus, genetic material and centrioles.

3. What happened to the cell after mitosis?

- The cell is then divided into two.

4. How many cell/s was/were there after undergoing mitosis?

- There are now two cells after mitosis.

5. Do/ Does the resulting have a nucleus, genetic material, and centrioles?
- Both of the cells have nucleus, genetic material, and centrioles.
30
Explai PPT
minut
n Slides
Stages of Mitosis es

You have just observed mitosis, or simply cell division. A cell becomes
two cells, then two cells become four, and so on. Mitosis is divided into
four stages: prophase, metaphase, anaphase, and telophase. In fact,
you’ve already seen how it happens in the previous video, but we will take
a look at each of the stages more closely.

PROPHASE: Centrioles move to the opposite poles of the cell.

METAPHASE: The chromosomes line up along the equator of the cell.
ANAPHASE: Chromosomes move away from each other.
TELOPHASE: The two groups of chromosomes reach the opposite ends
of the cell.

Cytokinesis
Keep in mind that mitosis itself is just the division of the nucleus, or the division of
the chromosomes in the nucleus. It is sometimes called nuclear division. How

SUBJECT (TEACHER’S NAME): 2

 about the cytoplasm? It divides too, doesn’t it? There is a name for its division.
It’s called cytokinesis or cytoplasmic division. After cytokinesis, the resulting
cells are called daughter cells.

So remember:
Mitosis Nuclear division
Cytokinesis Cytoplasmic division

Interphase
Mitosis is just one part of the cell cycle. The cell doesn’t really divide all the time.
It also needs time to rest and grow. Look at the image below. Observe that
generally, there are two phases, the non-dividing phase called the interphase,
and the dividing phase called mitosis.

The interphase begins with the G1 phase where the cell grows rapidly. It is
followed by the S phase where the DNA replicates or makes a copy of itself.
Why? Remember that after telophase, there’s only one set of chromosomes in
the newly-divided cell. To be able to do mitosis again, there must be two sets of
chromosomes in the nucleus, so the DNA has to replicate itself. After DNA
replication, the cell enters the G2 phase where growth and final preparations
before cell division occur.

Stem Cell Therapy

20
Elabor PPT
ate
Imagine a cell that can be “any cell.” It could become a muscle cell, a red Slides
minut
blood cell, a neuron, or any other. A cell that can differentiate into other es
types is called a stem cell. They are usually found either in an embryo or

SUBJECT (TEACHER’S NAME): 3

 in the bone marrow of adults. How important is it? For instance, if a stem
cell differentiates to a liver cell, that liver cell can then undergo mitosis and
grow in number. These cells become tissues, and these tissues become
an organ – a stem cell becomes a liver.

Stem cell therapy is used to repair tissues that are diseased or injured.
Scientists manipulate stem cells to differentiate into specific types of cells.
Think about it. If someone needs a liver, and there is no donor, stem cell
technology may be the solution.

I retrieved the picture here, but you may use others if you wish:
https://www.google.com/search?q=stem+cells&source=lnms&tbm=isch&s
a=X&ved=0ahUKEwiNsufGu-
PfAhVKMI8KHaAKAsMQ_AUIDigB&biw=1536&bih=754#imgrc=v3_0hQL22a-
RoM:

Math in Studying Cancer

Did you know that simply explained, cancer is uncontrolled mitosis? It

means the cell divides at a rate that does not follow the body’s control 15
Elabor PPT
ate
mechanism. In short, it is a cell division disorder. Slides
minut
Cancer scientists, also known as oncologists, investigate cancer by es
calculating the number of cells that result from mitosis in a particular
period of time.

SUBJECT (TEACHER’S NAME): 4

 Sharing words of encouragement is one of the best things you can give a
loved one, a friend, or even a stranger withcancer.

SUBJECT (TEACHER’S NAME): 5

 A. Write the term described by each of the following statements.

1. During this phase, the centrioles move to the opposite poles of the cell.
2. During this phase, the cytoplasm divides.
3. During this phase, the nuclear envelope reappears after the
chromosomes have moved toward each side of the cell.
4. During this phase, the chromosomes align along the equator of the cell.
5. During this phase, the cell grows and the DNA replicates itself.

B. Write True if the statement is True, if not write False.

1. Interphase is the first step in Mitosis.
2. When the cell split, it can produce 2 new cells.
3. During mitosis, some of chromosomes are missing.
4. During Anaphase, chromosomes move away from each other.
5. Centrioles move to the opposite poles of the cell during prophase.
10
Evalu PPT
Answer: minut
ate Slides
es
A.
1. Prophase
2. Cytoplasm
3. Telophase
4. Metaphase
5. Interphase
B.
1. False
2. True
3. False
4. True
5. True

Quick Teacher Self-Feedback:

___Debrief ___Re-Engage
___Re-Explore ___Have Students Clarify
___Build Knowledge More ___ Ready for Challenging Assessment
___Targeted 21st Century Skills ___ Developed Science Process Skills

Other Comments: __________________________________________

SUBJECT (TEACHER’S NAME): 6