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DAFTAR SINGKATAN

IARC : International Agency for Research on Cancer


Pca : Prostate Cancer
TURP : Transurethral Resection of the Prostate
ADT : Androgen Deprivasi Therapy
RTOG : Radiation Therapy Oncology Group
NCCN : National Comprehensive Cancer Network
EAU : European Association of Urology
IAUI : Ikatan Ahli Urologi Indonesia
PLAU : Urokinase-type plasminogen activator
MMP3 : Matrix metalloproteinase-3 (stromelysin 1,
progelatinase)
MPO : Myeloperoxidase
SERPINE1 : Plasminogen activator inhibitor 1
IGFBP3 : Insulin-like growth factor-binding protein 3
CYP1B1 : Cytochrome p450 family 1 subfamily b polypeptide 1
COMT : Catechol O-methyltransferase
AKR1C3 : Aldo-keto reductase family 1 member C3
AKR1C2 : Aldo-keto reductase family 1 member C2
HSD17B1 : Estradiol 17-beta-dehydrogenase 1
FLT1 : Vascular endothelial growth factor receptor 1
SYK : Spleen associated tyrosine kinase
TLR4 : Toll-like receptor 4
IL1B : Interleukin-1 beta
MET : Hepatocyte growth factor receptor
NOS3 : Nitric-oxide synthase, endothelial

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PIK3CD : Phosphatidylinositol 4,5-bisphosphate 3-kinase
catalytic subunit delta isoform
IKBKB : Inhibitor of nuclear factor kappa-B kinase subunit
beta
CHUK : Inhibitor of nuclear factor kappa-B kinase subunit
alpha
CYP19A1 : Catalyzes the formation of aromatic C18 estrogens
from C19 androgens
CYP17A1 : Steroid 17-alpha-hydroxylase/17,20 lyase
KDR : Vascular endothelial growth factor receptor 2
MMP9 : Matrix metalloproteinase-9
TNF : Tumor necrosis factor
IL2 : Interleukin-2
PIK3R1 : Phosphoinositide-3-kinase regulatory subunit
alpha/beta/delta
PPARG : Peroxisome proliferator-activated receptor gamma
MAPK8 : Mitogen-activated protein kinase 8
JAK1 : Tyrosine-protein kinase JAK1
NTRK1 : High affinity nerve growth factor receptor
INSR : Insulin receptor
FGF2 : Fibroblast growth factor 2
VEGFA : Vascular endothelial growth factor A
AKT1 : RAC-alpha serine/threonine-protein kinase
PIK3CB : Phosphatidylinositol-4,5-bisphosphate 3-kinase
catalytic subunit alpha/beta/delta
MAPK14 : Mitogen-activated protein kinase 14
JUN : Transcription factor AP-1
IGF1R : Insulin-like growth factor 1 receptor
PRKCA : Protein kinase C alpha type
AKT3 : RAC-gamma serine/threonine-protein kinase

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FLT3 : Receptor-type tyrosine-protein kinase FLT3
ITGB1 : Integrin beta-1
JAK2 : Tyrosine-protein kinase JAK2
EGFR : Epidermal growth factor receptor
CASP3 : Caspase-3
AR : Androgen receptor
AKT2 : RAC-beta serine/threonine-protein kinase
PIK3CA : Phosphatidylinositol 4,5-bisphosphate 3-kinase
catalytic subunit alpha isoform
MAPK9 : Mitogen-activated protein kinase 9
FGF1 : Fibroblast growth factor 1
KIT : Mast/stem cell growth factor receptor Kit
PTK2 : Focal adhesion kinase 1
ERBB2 : Receptor tyrosine-protein kinase erbB-2
PIK3CG : Phosphatidylinositol 4,5-bisphosphate 3-kinase
catalytic subunit gamma isoform
BCL2L1 : Bcl-2-like protein 1
HSP90AA1 : Heat shock protein HSP 90-alpha
MAP2K1 : Dual specificity mitogen-activated protein kinase
kinase 1
HRAS : GTPase HRas
CCND1 : G1/S-specific cyclin-D1
MAPK1 : Mitogen-activated protein kinase 1
ABL1 : Tyrosine-protein kinase ABL1
MCL1 : Induced myeloid leukemia cell differentiation protein
Mcl-1
MAPK10 : Mitogen-activated protein kinase 10
PRKACA : cAMP-dependent protein kinase catalytic subunit
alpha
PAK1 : Serine/threonine-protein kinase PAK 1

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PARP1 : Poly [ADP-ribose] polymerase 1
GSK3B : Glycogen synthase kinase-3 beta
RAF1 : RAF proto-oncogene serine/threonine-protein kinase
HDAC1 : Histone deacetylase 1/2
HSPA8 : Heat shock cognate 71 kDa protein
CDC25A : M-phase inducer phosphatase 1
CDK2 : Cyclin-dependent kinase 2
CDK4 : Cyclin-dependent kinase 4
BRAF : B-raf proto-oncogene serine/threonine-protein
kinase
PRKDC : DNA-dependent protein kinase catalytic subunit
CDK6 : Cyclin-dependent kinase 6
CDC25C : M-phase inducer phosphatase 3
CCNB1 : G2/mitotic-specific cyclin-B1
CCNA2 : Cyclin-A2
CCNE2 : G1/S-specific cyclin-E2
CDK1 : Cyclin-dependent kinase 1
CCNE1 : G1/S-specific cyclin-E1
CHEK1 : Serine/threonine-protein kinase Chk1
CCNA1 : Cyclin-A1
PLK1 : Serine/threonine-protein kinase PLK1

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