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Patho 828801 MCQS
Patho 828801 MCQS
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!! JAY AMBE !!
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MULTIPLE CHOICE QUESTIONS
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Pharm. D. 2nd Year
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Subject Name: Pathophysiology
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PREPARED BY
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DR. NAITIK D. TRIVEDI,
M. PHARM, PH. D
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PHARM. D 2ND YEAR PATHOPHYSIOLOGY - MCQ
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No. QUESTION
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1. Which of the following is not an aspect of the pathophysiology in disease.
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a. Causes
b. Pathogenesis
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c. Morphological changes
D.
d. Therapeutic treatment
2. Which of the following is a cell death?
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a. Apoptosis
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b. Lipolysis
c. Glycogenesis
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d. Gluconeogenesis
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3. Which of the following is physical agent of cell injury?
a. Hot Surface
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b. Dil. HCl
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c. Viruses
d. Hypoxia
4. Hypoxia is occurs in following condition except
a. Anaemia
b. Carbon monoxide poisoning
c. Lung disease
d. Thyroid disease
5. Iatrogenic causes means
a. Size of cell
b. Functions of cell
c. Phenotype of cell
d. All of the above
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7. Which of the above is not a cellular adaptation?
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a. Hyperplasia
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b. Metaplasia
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c. Hypoplasia
d. Hypertrophy
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D.
8. Ischemia causes following except
a. Decrease in activity of Na pump
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b. Increase Anaerobic Glycolysis
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c. Increase Cytosolic Calcium
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d. Detachment of Ribosome
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14. The edema is most likely the result of:
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a. Vasodilation
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b. Increased arterial hydrostatic pressure
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c. Increased vascular permeability
d. All of the above
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D.
15. The cell which lost ability to proliferate is called _____.
a. Stable
b. Labile
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c. Permanant
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d. All of the above
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16. Which of the following factors are delay the healing process?
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a. Infection
b. Poor blood supply
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c. Movement
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c. Human leukocyte Agent
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d. Human leukotrine Antigen
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21. What do you mean by autoimmune diseases?
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a. Hyper activity of immune responses
b. Hypo activity of immune responses
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D.
c. Decrease ability to identify between self & non -self
d. Increase ability to identify between self & non -self
22.
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Which of the following Antibody involve in Type-I ypersensitivity reaction?
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a. IgG
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b. IgM
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c. IgE
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d. IgA
23. Which immunoglobin is react with allergens?
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a. IgG
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b. IgM
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c. IgE
d. IgA
24. Rheumatoid Arthritis is a example of _________.
a. Type-I hypersensitivity
b. Type-II hypersensitivity
c. Type-III hypersensitivity
d. Type-IV hypersensitivity
25. Isografts are______________. *
a. Grafts in which the donor and recipient is the same individual.
b. Grafts between the donor and recipient of the same genotype.
c. Those in which the donor is of the same species but of a different genotype
d. Those in which the donor is of a different species from that of the recipient
26. Xenografts are______________.
a. Grafts in which the donor and recipient is the same individual.
b. Grafts between the donor and recipient of the same genotype.
c. Those in which the donor is of the same species but of a different genotype
d. Those in which the donor is of a different species from that of the recipient
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27. Which of the following part of the HIV is bind to CD4 receptor of of T per cell?
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a. gp120
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b. gp41
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c. p18
d. p24
N.
D.
28. HIV AIDS is a ______________disease.
a. Autoimmune
b. Immunodeficiency
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c. Hyper immunity
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d. All of above
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c. TTR
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d. APrP
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c) Severity of injury
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d) All of the above
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34. Cell swelling is a result of
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a) Decreased activity of sodium pump
b) Increased glycogen production
N.
D.
c) Decreased protein synthesis
d) Decreased lactic acid secretion
35.
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Which enzymes are responsible for removal of free radical
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a) Peroxidase
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b) Catalase
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c) Superoxide dismutase
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d) All of the above
36. Typhoid and paratyphoid are clinically indistinct
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a) True
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b) False
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c) 1-2 days
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d) 7-9 days
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41. Which of the following symptom does not appear during first week of infection in typhoid?
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a) Fever
b) Myalgia
N.
D.
c) Diarrhoea in children
d) Delirium
42.
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Which serological test can be used for diagnosis of typhoid fever?
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a) Widal test
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b) PCR
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c) ELISA
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d) None of the above
43. Which antibiotic can be employed for treatment of typhoid fever?
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a) Ciprofloxacin
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b) Azithromycin
DR
c) Tetracycline
d) Lincosamide
44. Which of the following drug cannot be given in bacillary dysentery
a) Sulfamethoxazole
b) Ciprofloxacin
c) Diphenoxylate
d) None of the above
45. Bacillary dysentery is a self limiting disease
a) True
b) False
46. In bacillary dysentery usually patient experience symptoms within hours of ingestion of
contaminated food and water
a) 72 hours
b) 96 hours
c) 24 hours
d) 12 hours.
47. Parkinson disease is marked by a lack of which chemical in the brain?
a) Serotonin
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b) GABA
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c) Dopamine
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d) Norepinephrine
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48. Ischamic stroke happens when ______________.
a) The brain's blood vessels become narrowed or blocked
N.
D.
b) Internal bleeding in brain
c) Both A & B
d) Neither A nor B
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49. What is hallucination?
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a) False beliefs that are not based in reality.
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_________________.
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a) Alzhiemer
b) Parkinson
c) Stroke
d) Depression
51. Bipolar disorder formerly called ___________.
a) Mania
b) Parkinson’s
c) Schizophrenia
d) Alzheimer
52. In hyper - dynamic hypertension cardiac output is increase due to an increase in either heart
rate or extracellular volume, leading to an increased venous return and thus an increased
stroke volume called____________.
a) Hematocrit mechanisms
b) Autoregulatory mechanisms
c) Frank–Starling mechanism
d) None of above
53. Angina pectoris is the result of myocardial ischemia caused by an imbalance between
myocardial blood supply and oxygen demand.
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a) True
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b) False
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54. _______known as the left ventricular end-diastolic pressure (LVEDP), is the amount of
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ventricular stretch at the end of diastole.
a) Preload
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b) Afterload
c) Cardiac output
d) Cardiac index
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55. The transmural infarcts involving____________________.
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a) The full thickness of ventricular wall
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56. The plaques with thicker fibrous caps tend to cause more pronounced arterial narrowing,
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a) Vulnerable plaque
b) Stable plaque
c) Unstable plaque
d) None of above
57. The major transporter used for uptake of glucose called _________.
a) GLUT4
b) GLUT3
c) GLUT2
d) GLUT1
58. The_____protein is made up of complete immunoglobulin light chains.
a) AL
b) AA
c) Aβ
d) All of above
59. _________protein of the HIV virion combines with CD4 receptor.
a) gp120
b) gp41
c) gp121
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d) gp42
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60. Full form of AIDS________
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a) Adaptive Immune Deficiency Syndrome
D.
b) Acquired Immune Deficiency Syndrome
c) Acute Immune Deficiency Syndrome
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d) Acquired Immune Direct Syndrome
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61. Increase dopaminergic transmission into mesolimbic system______ shows positive system in
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a. Depression
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b. Alzheimer
c. Parkinson’s
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d. Schizophrenia
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62. The part of the brain get most affected in Parkinson’s disease is____.
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a. Corpus striatum
b. Putamen
c. Substantia nigra
d. Thalamus
63. An ischemic stroke occurs ____.
a. When an artery in the brain becomes blocked
b. When bleeding start from blood vessels
c. Due to infection
d. All of above
64. A decreased dopamine activity specifically which corresponds to the inability to experience
pleasure which is one of the hallmarks of________.
a. Depression
b. Alzheimer
c. Parkinson’s
d. Schizophrenia
65. Decreased ____ function accompanies manic and depressive states.
a. GABAergic
b. Serotonergic
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c. Adrenergic
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d. All above
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66. In hyper - dynamic hypertension cardiac output is increase due to an increase in either heart
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rate or extracellular volume, leading to an increased venous return and thus an increased
N.
stroke volume called____________.
D.
a. Hematocrit mechanisms
b. Autoregulatory mechanisms
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c. Frank–Starling mechanism
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d. None of above
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67. Atherosclerotic narrowing of __________leads angina.
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a. Coronary Artery
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b. Coronary Vein
c. Aorta
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d. All Of Above
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d. Soft speech
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72. Hallucinations means________.
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a. Hearing or seeing things that don't exist
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b. These are false beliefs that are not based in reality
c. The person may jump from one subject to another for no logical reason.
N.
D.
d. Disorganized thinking is inferred from disorganized speech.
73. Depression may be due________________.
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a. To have physical changes in the brains.
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b. Abnormal level of brain chemicals.
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c. Changes in the body's balance of hormones
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d. All of above
NA
74. The normal BP is ___________systolic &___________diastolic.
a. 120 mmHg, 80 mmHg
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b. Duration of injury
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c. Severity of injury
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d. All of the above
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79. Cell swelling is a result of
a. Decreased activity of sodium pump
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D.
b. Increased glycogen production
c. Decreased protein synthesis
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d. decreased lactic acid secretion
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80. Which enzymes are responsible for removal of free radical
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a. Peroxidase
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b. Catalase
NA
c. Superoxide dismutase
d. All of the above
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a. True
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b. False
82. Salmonella is spread by
a. Flies
b. Fomites
c. Feces
d. All of the above
83. The occurrence of typhoid is high in following circumstances except
a. Use of narrow spectrum antibiotic
b. Living with poor sanitation
c. Comes in contact with infected person
d. None of the above
84. The pathogenesis of typhoid fever depends on following except
a. Infectious species
b. Virulence
c. Host immunity
d. Volume of organism
85. The typical incubation period of salmonella is
a. 10-14 days
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b. 2-3 days
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c. 1-2 days
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d. 7-9 days.
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86. Which of the following symptom does not appear during first week of infection in typhoid?
a. Fever
N.
D.
b. Myalgia
c. Diarrhoea in children
d. Delirium
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87. Which serological test can be used for diagnosis of typhoid fever?
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a. Widal test
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b. Pcr
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c. Elisa
d. None of the above
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a. Ciprofloxacin
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b. Azithromycin
c. Tetracycline
d. Lincosamide
89. Which serological test can be used for diagnosis of typhoid fever?
a. PCR
b. ELISA
c. Widal Test
d. HRCT
90. The occurrence of typhoid is high in following circumstances except
a. Use of narrow spectrum antibiotic
b. Living with poor sanitation
c. Comes in contact with infected person
d. Eating contaminated food
91. Which of the following is not a type of cellular adaptation?
a. Hypertrophy
b. Atrophy
c. Hyperplasia
d. Superplasia
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92. Cell swelling is a result of
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a. Decresed activity of Sodium pump
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b. Increased glycogen Production
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c. Decreased Protein Synthesis
d. Decresed Lactic acid secretion
N.
D.
93. Which of the following drug cannot be given in bacillary dysentery?
a. Sulfamethoxazole
b. Ciprofolxacin
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c. Diphenoxylate
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d. Cotrimoxazole
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d. Inadequate Nutrition
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95. Which of the following enzyme is not responsible for removal of free radical?
a. Peroxidase
b. Catalase
c. Hexokinase
d. Superoxide dismutase
96. Which of the following symptom does not occur in the first week of infection in typhoid?
a. Fever
b. Delirium
c. Myalgia
d. Diarrhoea
97. Which of the following is an Iatrogenic cause of Cell Injury
a. Death due to error in judgment by the physician
b. Death due to Carbon monoxide Poisoning
c. Death due to Road accident
d. Death due to Viral infection
98. The redness and heat of an inflamed area is due to a local hyperaemia caused by
a. Vasodilatation
b. Vasoconstriction
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c. Phagocytic aggregation
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d. Production of antibodies
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99. Which of the following vitamin helps in blood clotting?
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a. Vitamin A
b. Vitamin C
N.
D.
c. Vitamin D
d. Vitamin K
100.
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Which is the leading cause of blindness in children worldwide?
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a. Glaucoma
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b. Cataracts
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c. Colour blindness
NA
d. Vitamin A deficiency
101. Which of the following vitamin deficiency causes Beriberi?
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a. Vitamin B1
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b. Vitamin B2
DR
c. Vitamin B6
d. Vitamin B12
102. Which of the following vitamins serves as a hormone precursor?
a. Vitamin A
b. Vitamin C
c. Vitamin D
d. Vitamin K
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