Hematology Osmosis HY Pathology Notes ATF

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Hematology

High Yield
Notes
by
AfraTafreeh.com

Pathology
Table of Contents
Congenital Anemia 1
Overview 2
Diamond-Blackfan Anemia 2
Fanconi Anemia (FA) 4

Dysplastic & Proliferative Disorders 6


Essential Thrombovytosis 7
Langerhans Cell Histiocytes 8
Leukemoid Reaction 10
Myelodysplastic Syndrome 11
Polycythemia Vera 12
Primary Myelofibrosis 14
D&P disorders overview 15

Hypercoagulable Disorders 16
Antiphospholipid Syndrome 17
Antithrombin III Deficienct 18
Factor V Leiden FVL 19
Protein C Deficiency 20
Protein S Deficiency 21

Hypocoagulable Disorders 22
Disseminted Intravascular Coagulation 22
Hemophilia A 24
Hemophilia B 25
Von Willebrand Disease 26

Leukemias 27
Acute Lymphoid Leukemia 28
Acute Myeloid Leukemia 29
Chronic Lymphoid Leukemia 31
Chronic Myeloid Leukemia 33
Characteristics of CML 34
Table of Contents
Lymphomas 35
Hodgkin’s vs Non-Hodgkin’s Lymphoma 36
Hodgkin’s Lymphoma 36
Non-Hodgkin’s Lymphoma 38
Types of NHL 39

Macrocytic Anemia 42
Megaloblastic Anemia 42
Sideroblastic Anemia 44

Methemoglobinemia 46

Microcytic Anemia 48
Iron-Deficiency Anemia 49
Lead Poisoning-Related Anemia 50
Thalassemia 51

Normocytic Anemia (Decreased Hemolysis) 54


Anemia of Chronic Disease 54
Aplastic Anemia 56

Normocytic Anemia (Increased Hemolysis) 58


Autoimmune Hemolytic Anemia (AHA) 58
Classification 59
Glucose-6-Dehydrogenase Deficiency 60
Hemolytic Disease of the Newborn 62
Hereditary Spherocytosis 64
Paroxysmal Nocturnal Hemoglobinuria (PNH) 65
Pyruvate Kinase Deficiency 67
Sickle Cell Anemia 68

Plasma Cell Dyscrasias 71


Monoclonal Gammopathy of Undetermined Significance MGUS 71
Multiple Myeloma 72
Table of Contents
Waldenstorm Macroglobulinemia 75

Platelet Disorder 77
Bernar-Soulier Syndrome 77
Glanzmann’s Thrombasthenia 78

Porphyria 80
Acute Intermittent Porphyria 81
Porphyria Cutanea Tarda 82

Spleen Pathology 84
Asplenia 85
Ruptured Spleen 86
Spleenic Injury Scale 87

Thrombocytopenia 88
Heparin-Induced Thrombocytopenia 88
HIT Types 89
Idiopathic Thrombocytopenic Purpura 90
Thrombotic Thrombocytopenic Purpura 92
Lab values in TTP 93

Thymus Neoplasia 94
Thymoma 95
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