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COURSE SYLLABUS
in
BIO 608
ADVANCED GENETICS
2nd Semester A.Y. 2018-2019

Department Area : Sciences

Curriculum : MA Ed- major in Science Teaching
Curriculum Year : 2018-2019
Number of Hours per Semester : 54 hours
Credit units : 3
Prerequisite : General Biology 1, Fundamentals of Animal Biology, General Biology 2

Vision of the University : A premier multidisciplinary technological university

Mission of CTU : The University shall provide advanced professional and technical instruction for special purposes , advanced studies in
industrial trade, teacher education, agriculture, fishery, forestry, engineering, aeronautics and land-based programs, arts
and sciences, health and sciences, information technology and other relevant fields of study. It shall also undertake
research, production and extension services, and provide progressive leadership across the areas of specialization for
global empowerment.

Mission of the Graduate School : The Graduate School develops technology and value-oriented executive leaders in education, agri-industrial, and related
Sectors through research and community services toward shared productivity in their chosen fields.

Goals of the College : 1. Provide complementation and continuity of the undergraduate programs.
2. Cater the needs of the value-oriented educational leaders/technologist who are and would be occupying managerial
position in higher educational institutions, technical-vocational institutions, industry, agriculture, fishery and related
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sectors;
3. Contribute to the attainment of regional and national goals through the promotion of educational and applied
researches towards quality life;
4. Accelerate high level professionalism and globally competitive technology culture

Program Outcomes : PO 1 Conduct of publishable quantitative or qualitative research towards authentic educational services, public
governance, technology transfer and productivity
PO 2 Development of decision-making abilities through the use of quantitative analysis
PO 3 Validation of theories towards exemplification of models, programs and practices
PO 4 Recognition of professional, social, and ethical responsibilities
PO 5 Ability to solve current problems that deal with complex issues related to the discipline
PO 6 Innovation of teaching approaches and resources
PO 7 Undertaking specialized trainings to enrich knowledge and skills
PO 8 Contribution to the continued improvement of teaching and learning in the classroom
PO 9 Use of developmentally appropriate methods to design and deliver instruction in science
PO 10 Planning and implementing appropriate scientific investigations to develop problem solving and critical thinking
skills in science
PO 11 Establishment of procedures that enhance the organization and management of the science classroom
PO 12 Creation of appropriate evaluative measure to improve science instruction
PO 13 Development of strategies to address science topics that are controversial to diverse groups

Course Description : The course is an advanced discussion about the mechanisms of heredity and variation. In here, students will appreciate
the diversity among human as well as plant population through gene interaction. New trends in technology will be
introduced such as karyotyping and genetic engineering to better appreciate the uniqueness of life in all its full splendour.

Course Learning Outcomes : At the end of the course, the students will be able to:

1. illustrate chromosomal behaviour during mitosis and meiosis in somatic and germ cells;
2. explain the basic concepts underlying heredity and variation in Mendelian and non-Mendelian inheritance;
3. connect the structures of DNA to its functions and mechanisms by which it fulfils them;
4. compare and contrast prokaryotic and eukaryotic gene expression;
5. describe the sources of variation among individuals ;
6. appraise the mechanism of inheritance , use of pedigree, distinguish genetic control of certain genetic disorders and evolutionary influences that govern
both plants and animals.
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Course Content:

Intended Learning Outcomes Assessment Teaching – Contents Learning Reference Time Remarks
Tasks Learning Resources Allocation
Activity
At the end of the course, the
students are able to: CTU student
manual CTU 1 hour
Relate the course to CTU Vision, Group Lecture- Mission, Vision, Goals of CTU student’s
Mission and Goals and to the Sharing of discussion College manual
Objectives of the Graduate School Aspirations bulletin
VMG and Objectives in one’s life

Umaly, R.C.
At the end of the lesson, students 1986.
are able to: Written task Lecture Lecture 2 hours
discussion LCD Notes on
 Define and appraise the fields  Definition of Genetics projector Modern
and methods of genetic study o Fields of Genetics Genetics.
o Methods of Genetic 2nd ed.
Study Vol.1. Vibal
Publishing
House, Inc.,
Metro
Manila.
 Enumerate, describe and Written task Lecture-  Chromosome and Cell Cycle LCD 6 hours
discuss the functions of the discussion o Cell: its organelle and projector Starr, C,
Evers, C. &
different parts of the cell functions Starr. L. 2016.
o Types and structural Biology: Today
 Discuss the cell cycle, mitosis features of and Tomorrow.
and meiosis chromosomes 5th ed.
Cengage
o Cell Cycle Learning Asia
o Mitosis Pte
o Meiosis Ltd,Singapore
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Intended Learning Outcomes Assessment Teaching – Contents Learning Reference Time Remarks
Tasks Learning Resource Allocation
Activity
 Chromosomal basis of sex Umaly, R.C.
determination 1986.
 Differentiate the various bases Written task Lecture- o The sex chromosomes Lecture
in chromosomal determination and oral discussion o Sex ratios Notes on
in both plants and animals reporting o Nuclear sex Modern
o Sex chromosomal Genetics. 3 hours
aberrations LCD 2nd ed.
o Post genetic sex in projector Vol.1. Vibal
Publishing
humans
House, Inc.,
o Sex determination in
Metro
other animals
Manila.
o Sex determination in
plants

 Autosomal Chromosomal Umaly, R.C.

Aberrations 1986.
 Compare the various autosomal Written task Lecture- o Significance of Lecture
chromosomal aberrations and oral discussion chromosomal LCD Notes on 3 hours
reporting aberrations projector Modern
o Change in chromosome Genetics.
number 2nd ed.
o Structural abnormalities Vol.1. Vibal
Publishing
House, Inc.,
Metro
Manila.
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Intended Learning Outcome Assessment Teaching Contents Learning References Time Remarks
Tasks Learning Resources Allocation
Activity
 Mendelian Inheritance Umaly, R.C.
 Explain the concepts of heredity Written task Lecture- o Monohybrid 1986.
and variation in Mendelian and oral discussion Experiments Lecture
inheritance reporting o Present interpretation of Notes on
monohybrid crosses Modern 6 hours
o Testing genotypes LCD Genetics.
o Examples of simple projector 2nd ed.
Mendelian traits Vol.1. Vibal
o Dihybrid crosses Publishing
House, Inc.,
o Tri and Polyhybrid
Metro
crosses
Manila.

 Probability, Genetic Ratios and Umaly, R.C.

Test of Significance 1986.
 Give the significance of genetic Written task Lecture- o Genetic ratios and Lecture
probability and test of and oral discussion probability Notes on
significance reporting o Binomial distribution Modern
o Test of statistical LCD Genetics. 6 hours
significance projector 2nd ed.
o Confidence limits Vol.1. Vibal
o The Chi-square test Publishing
House, Inc.,
o The Contingency factor
Metro
for ᵡ 2
Manila.
o Non- Mendelian
inheritance
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Intended Learning Outcomes Assessment Teaching Contents Learning References Time Remarks
Tasks Learning Resources Allocation
Activity
 Dominance Relations and Umaly, R.C.
Multiple Alleles 1986.
 Discuss by giving sample Written task Lecture- o Incomplete dominance Lecture
problems on genetic and oral discussion or Intermediateness Notes on
dominance and role of multiple reporting o Codominance Modern
alleles in the transmission of o Medico-Legal Genetics. 3 hours
genes implications of Genetics LCD 2nd ed.
Assignment: of blood typing projector Vol.1. Vibal
 Pedigree o The RH factor Publishing
analysis o Other blood groups House, Inc.,
of one’s Metro
o Histocompatibility of
family Manila.
genes
tree
o Multiple allelism in other
traits

M I D T E R M E X A M
 Polygenic Inheritance Umaly, R.C.
 Differentiate inheritance of Written task Lecture- o Polygenes and 1986.
polygenic genes in humans and oral discussion continuous traits Lecture
reporting o Skin color inheritance in Notes on
humans LCD Modern 3 hours
o Multiple genes in plants projector Genetics.
o Modifications of the 2nd ed.
additive effects Vol.1. Vibal
o Discontinuous traits Publishing
House, Inc.,
Metro
Manila.
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Intended Learning Outcomes Assessment Teaching- Contents Learning References Time Remarks
Tasks Learning Resources Allocation
Activity
 Gene Interactions, Lethality, Umaly, R.C.
Environmental Effects and 1986.
 Predict gene interactions and Written task Lecture- Heritability Lecture
influence of the environment in and oral discussion o Epistasis Notes on
changing gene pool reporting o Suppressors and other Modern
modifiers Genetics.
o Penetrance and 2nd ed.
expressivity LCD Vol.1. Vibal 3 hours
Assignment: o Lethal and sublethal projector Publishing
 Effects of genes House, Inc.,
cell o Environmental effects Metro
phones on Manila.
o Heritability
human
o Twin studies
genes
o Adoption studies

 Sex Related Inheritance Umaly, R.C.

o Autosomal genes and 1986.
 Enumerate and describe sex Written task Lecturer- reciprocal crosses Lecture
related inheritance and oral discussion o X-linked genes Notes on
reporting o Y-linked genes LCD Modern 3 hours
o Sex-linked genes projector Genetics.
Assignment: o ZZ system 2nd ed.
 Enumerat Vol.1. Vibal
o Sex-influenced traits
e& Publishing
o Sex-Limited traits
discuss House, Inc.,
examples Metro
of sex- Manila.
influenced
traits
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Intended Learning Outcomes Assessment Teaching- Contents Learning References Time Remarks
Tasks Learning Resources Allocation
Activity
 Linkage and Chromosome Umaly, R.C.
Mapping 1986.
 Comprehend by differentiating Written task Lecture- o Linkage Lecture
chromosome mapping among and oral discussion o Detection of linkage Notes on
diploid organisms reporting o Arrangement of Linked LCD Modern 3 hours
Genes projector Genetics.
o Crossing over 2nd ed.
o Gene mapping in diploids Vol.1. Vibal
Publishing
House, Inc,
Metro
Manila.
 Extrachromosomal Inheritance Umaly, R.C.
o Nomenclature 1986.
 Recognize the role of Written task Lecture- o Physical continuity of Lecture
chromosomes in inheritance and oral discussion extrachromosomal Notes on
reporting hereditary factors Modern
o Genetic continuity of Genetics.
extrachromosomal 2nd ed.
structures Vol.1. Vibal 3 hours
o Maternal inheritance LCD Publishing
o Extrachromosomal projector House, Inc,
Metro
change and mutation
Manila.
o Extrachromosomal
segregation
o Chromosomal gene and
extrachromosomal
interaction
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Intended Learning Outcomes Assessment Teaching- Contents Learning References Time Remarks
Tasks Learning Resources Allocation
Activity
 Hardy-Weinberg Law of Umaly, R.C.
Genetic Equilibrium 1986.
 Scrutinize Hardy-Weinberg law Written task Lecture- o Mendelian genetic Lecture
of genetic equilibrium and oral discussion population Notes on
reporting o Gene frequencies Modern
o Hardy – Weinberg Law Genetics. 3 hours
o Case of complete LCD 2nd ed.
dominance projector Vol.1. Vibal
o Case of di- and multi- Publishing
House, Inc,
hybrid
Metro
o Multiple alleles
Manila.
o X-linked genes
o Sex influenced traits
o Linked genes

 Alteration of Genetic Umaly, R.C.

Equilibrium 1986.
 Analyse the various alteration Written task Lecture- o Change of genetic Lecture
of genetic equilibrium and oral discussion frequencies: Systematic Notes on
reporting and dispersive Modern
processes LCD Genetics. 3 hours
o Role of mutation projector 2nd ed.
o Role of selection Vol.1. Vibal
o Role of migration Publishing
o Random genetic drift House, Inc,
Metro
o Non-panmictic mating
Manila.
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Intended Learning Outcomes Assessment Teaching- Contents Learning References Time Remarks
Tasks Learning Resources Allocation
Activity
 Genetics, Evolution and Umaly, R.C.
 Interpret and predict heredity of Written task Lecture- Eugenics 1986.
organisms and the ability to and oral demonstration o “Best Fit” Lecture
evolve through time given the reporting o Natural selection, Notes on
quality of life situation at its change in gene LCD Modern 3 hours
optimum frequency and evolution projector Genetics.
o Race formation 2nd ed.
o Speciation Vol.1. Vibal
o Eugenics Publishing
House, Inc,
Metro
Manila.
F I N A L E X A M
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Course Requirements : Oral reporting (selected topics found on the syllabus)

Submission of a critique paper on current trends in Genetics research in the Philippines

Evaluation Procedure : Major examination - 40 %

Oral presentation - 30 %

Written tasks - 30 %
100 %

Prepared by : EMMANUEL A. PARDIÑAN, M.Sc., D.O.D.

Date submitted : January 2, 2019

Upon the recommendation by the Curriculum Committee:

ALMA D, AGERO, Ed.D. HEDELIZA A. PINEDA, Ph.D. EDWIN A. PILAPIL, Ed. D.

Member Member Chairman

APPROVED BY:
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REBECCA DC. MANALASTAS, Ph.D.

Dean, Graduate School