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    NO, TNF-α, IL-1β……ect: Nfkb, Mapk

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    abdul razak

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    NO, TNF-α, IL-1β……ect: Nfkb, Mapk

    Uploaded by

    abdul razak
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    NO, TNF-α, IL-1β……ect: Nfkb, Mapk

    Uploaded by

    abdul razak

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    © All Rights Reserved
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    of 1

    Flavonoid,

    Terpenoid Flavonoid

    NFKB,
    MAPK

    3
    CL
    AL

    Pro Inflamatory
    neurodegen
    mediator NO,
    erasi
    TNF-α, IL-
    1β……ect

    Terpenoid, Disfungsi
    Alkaloid saraf
    Peningkatan Stress
    oksidatif ( ↑ ROS)
    Penurunan
    fungsi

    Merusak biomolekuls sel


    ( lipid , protein, DNA)

    DEMENSIA

    Kerusakan sel saraf Penurunan neurotransmiter

    Terpenoid
    Flavonoid,
    fenolik Donepezil

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