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Eyes
Eyes
Function:
Ø The iris controls the amount of light that enters the eye by
opening and closing the pupil. The iris uses muscles to
change the size of the pupil.
PUPIL
• Rounded opening of the iris through which light passes
• Are the black center of the eye.
• Pierces the iris diaphragm slightly below and nasal to its
centre, but lying on the optical axis behind the cornea.
Function:
Øto let in light and focus it on the retina (the nerve cells
at the back of the eye) so you can see.
ØThe iris and the pupil control how much light to let into
the back of the eye. When it is very dark, our pupils are
very large, letting in more light.
SCLERA
• A tough white skin (made of tissue) that covers all of the
eyeball except the cornea.
• Is the thickest posteriorly and gradually becomes thin when
traced anteriorly.
• Forms posterior 5/6th of external tunic, connective tissue of
the eyeball.
• It continues with durameter and cornea.
• Anteriorly covered by bulbar conjunctiva
• Inner Surface lies in contact with choroid
• With a potential suprachoroidal space in between.
Function:
Ø Supports eyeball and provides attachment for the muscles
THICKNESS OF SCLERA
• Thickness varies with individual, with age
• Thinner-children, elder, F>M
• Thickest posteriorly
• Gradually becomes thinner when traced anteriorly.
• Think at insertion of extraocular muscle
SPECIAL REGIONS OF SCLERA
• Tenon’s Capsule
Ø Fascial sheath of the eyeball
Ø Also known as fascial bulbi, capsul
of tenon, bulbar sheath.
Ø It’s a thin fibrous membrane
envelops the eyeball from optic nerve
to limbus.
SPECIAL REGIONS OF SCLERA
• Lamina Cribrosa- It is a sieve-like sclera from which the fibres of the topic
nerve pass.
SCLERA
Thin, dense
Avascular stucture- dense Innermost blends with
vascularised layer of
bundles of collagen fibers suprachoridal and supraciliary
connective tissue-
laminae of the uveal tract.
fibroblasts.
Brownish in color
Macrophages and
Presence of pigmented cells
lymphocytes
CONJUNCTIVA (OVER SCLERA)
• The conjunctiva is the mucous membrane of the
eye. It lines the inner surfaces of the eyelids or
palpebræ, and is reflected over the forepart of the
sclera and cornea. The conjunctiva helps lubricate
the eye by producing mucus and tears, although a
smaller volume of tears than the lacrimal gland.
Function:
Ø The conjunctiva of the eye provides protection and
lubrication of the eye by the production of mucus and
tears. It prevents microbial entrance into the eye and
plays a role in immune surveillance. It lines the inside of
the eyelids and provides a covering to the sclera.
EYELASHES
• Secretes oil that prevents lid from sticking
together.
• Are attached to the free edges of the
eyelids; they are short, thick, curved hairs,
arranged in a double or triple row: those
of the upper eyelid, more numerous and
longer than those of the lower, curve
upward; those of the lower eyelid curve
downward, so that they do not interlace
in closing the lids.
Function:
ØThey function to protect the eye from
debris.
EYELIDS
• An eyelid is a thin fold of skin that
covers and protects an eye. The levator
palpebrae superioris muscle retracts the
eyelid, exposing the cornea to the
outside, giving vision. This can be either
voluntarily or involuntarily.
Function:
ØThe human eyelid features a row of
eyelashes along the eyelid margin,
which serve to heighten the protection
of the eye from dust and foreign debris.
UPPER EYELID LOWER EYELID
(PALPEBRA) (PALPEBRA)
Function:
ØPrevents internal reflection light and nourish
retina.
CORNEA
• Is the transparent part of the eye that covers the front portion of
the eye. It covers the pupil (the opening at the center of the eye),
iris (the colored part of the eye), and anterior chamber (the
fluid-filled inside of the eye).
• The word cornea has come from “Kerato”. It means horn or
shield like. Ancient Greek used to beleive that cornea is derived
from same material like that of thibly sliced horn of animal.
Functions:
Ø Bends incoming light focusing it on the retina.
Ø The cornea acts as the eye's outermost lens. It functions like a
window that controls and focuses the entry of light into the eye.
The cornea contributes between 65- 75 percent of the eye's
total focusing power.
RETINA
• The retina is a thin layer of tissue that lines
the back of the eye on the inside. It is located
near the optic nerve. The purpose of
the retina is to receive light that the lens has
focused, convert the light into neural signals,
and send these signals on to the brain for
visual recognition.
Function:
Ø The purpose of the retina is to receive light
that the lens has focused, convert the light
into neural signals, and send these signals on
to the brain for visual recognition.
RETINA
• Color: Pale Pink
• 1.5 mm diameter, well defined circular area
OPTIC DISC • At the optic disc-All retinal layers terminate except nerve fibers, which pass
through the lamina cribrosa to run into optic nerve.
• Physiological Cup: Depression seen it. Central retinal vessels emerge through
the centre of this cup.
Function:
Ø A tiny area densely packed cones for detailed and coloured vision.
Ø The fovea is responsible for sharp central vision (also
called foveal vision), which is necessary in humans for reading,
driving, and any activity where visual detail is of primary
importance.
BLINDSPOT
• Is where the optic nerve and blood vessels leave the
eyeball. The optic nerve is connected to the brain. It
carries images to the brain, where they're processed. This
is how we know what we're seeing. Our eyes see the
object or image, and our brain interprets it.
• Is an area in your range of vision that you cannot see
properly but which you really should be able to see. For
example, when you are driving a car, the area just behind
your shoulders is often a blind spot.
Function:
ØExit point of the optic nerve cutting through the retina so
no rods or cones.
OPTIC NERVE
• The optic nerve is located in the back of the eye.
It is also called the second cranial nerve or cranial
nerve II. It is the second of several pairs of cranial
nerves.
• The optic nerve is made of ganglionic cells or
nerve cells. It consists of over one million nerve
fibers. Our blind spot is caused by the absence of
specialized photosensitive (light-sensitive) cells, or
photoreceptors, in the part of the retina where
the optic nerve exits the eye.
Function:
ØThe job of the optic nerve is to transfer visual
information from the retina to the vision centers
of the brain via electrical impulses.
OPTIC NERVE
ØThese branches include the central retinal artery, the short and long
posterior ciliary arteries, and the anterior ciliary arteries.
ØVenous outflow from the eye is primarily via the vortex veins and the
central retinal vein, which merge with the superior and inferior
ophthalmic veins that drain into the cavernous sinus, the pterygoid
venous plexus and the facial vein.
Ø In some species (e.g., rodents and lagomorphs), the orbital veins
form a sinus.
ARTERIAL SUPPLY OF THE EYE
§ Internal carotid artery is first intracranial branch of the internal carotid just as the artery exits from the cavernous sinus .
It is the optic foramen below and lateral to the optic nerve. It Pass over the optic nerve to its medial side and terminates
by dividing into dorsonasal and supratrochlear Ophthalmic artery:
§ The retina is supplied by the central retinal artery and the short posterior ciliary arteries. The central retinal artery
travels in or beside the optic nerve as it pierces the sclera then branches to supply the layers of the inner retina (i.e., the
layers closest to the vitreous compartment).There are marked species differences in the inner retinal vascularization,
with primates having a complex 4-zone arrangement and an avascular zone at the fovea, lagomorphs having a rather
simple narrow band of superficial vessels, rodents having a wagon-wheel spoke-like arrangement and guinea pigs having
no inner retinal vessels
§ The short posterior ciliary arteries (typically 6-12) pierce the sclera around the optic nerve then arborize to form the
arterioles of the dense outer layer of conduit vessels of the choroid . The arterioles the give off roughly perpendicular
terminal arterioles that supply lobules of choriocapillaries that comprise the sheet-like layer of the choriocapillaris
adjacent to Bruch’s membrane, the retinal pigment and the outer segments of the photoreceptors
§ The vascular supply of the optic nerve is complex. The optic nerve has three zones referenced to the lamina cribosa, the
connective tissue extension of the sclera through which the optic nerve axons and the central retinal artery and vein pass.
The prelaminar (i.e., inside the eye relative to the lamina cribosa) optic nerve is supplied by collaterals from the choroid
and retina circulations. The laminar zone is supplied by branches from the short posterior ciliary and pial arteries. The
post laminar zone is supplied by the pial arteries.
ATERIAL SUPPLY SUMMERY TABLE
VENOUS DRAINAGE
• The central retinal vein runs through the optic nerve. From here it drains into the cavernous sinus
or superior ophthalmic vein. The superior ophthalmic vein is usually the largest and is the principal vein. It is
formed when the supraorbital and angular veins unite just behind the trochlea (pulley like structure). The
veins that drain into it are named as the arteries of the region (medial palpebral, lacrimal, anterior
ethmoidal, inferior ophthalmic, central retinal and muscular).
• The inferior ophthalmic vein runs over the surface of the inferior rectus muscle, and drain to the cavernous
sinus or the superior ophthalmic vein. It drains the inferior rectus muscle, inferior oblique muscle, lacrimal
sac and lower lid.
• The retina is drained by the retinal veins and venules, which run from the peripheral retina toward the optic
nerve head. The venous circle they form at the optic disc may be complete or incomplete in the dog. The
venous circle drains posteriorly through the sclera via the posterior ciliary veins to a dilation in the orbital
vein, the superior (dorsal) ophthalmic vein.
• The choroid is drained by approximately four vortex veins, which leave the globe near the equator and join
the superior and inferior ophthalmic veins. The ciliary body is drained by the anterior ciliary veins to the
same superior and inferior ophthalmic veins that drain to the orbital venous plexus at the apex of the orbit.
• This plexus drains to the cavernous venous sinus within the cranial vault. The cavernous sinus drains via
the vertebral sinuses, external jugular vein, and internal maxillary vein. Venous blood thus passes
posteriorly from the orbit via this route. It may also pass anteriorly via anastomoses between the
ophthalmic veins and the malar, angularis oculi, and facial veins to the external maxillary and external
jugular veins.
VENOUS
DRAINAGE TABLE
SUMMERY
LENS
• Lens, in anatomy, a nearly transparent biconvex structure suspended behind the iris of the eye, the sole
function of which is to focus light rays onto the retina.
• . By changing shape, it functions to change the focal length of the eye so that it can focus on objects at
various distances, thus allowing a sharp real image of the object of interest to be formed on the retina. This
adjustment of the lens is known as accommodation. Accommodation is similar to the focusing of a
photographic camera via movement of its lenses. The lens is flatter on its anterior side than on its posterior
side.
• . The lens is made up of unusual elongated cells that have no blood supply but obtain nutrients from the
surrounding fluids, mainly the aqueous humour that bathes the front of the lens. Waste products are
removed through these fluids as well. The shape of the lens can be altered by the relaxation and contraction
of the ciliary muscles surrounding it, thus enabling the eye to focus clearly on objects at widely varying
distances. The ability of the lens to adjust from a distant to a near focus, called accommodation, gradually
declines with age (a condition called presbyopia), often requiring correction. Clouding or opacity of the lens,
called a cataract, may also occur with age. Cataracts that interfere with vision can be corrected by surgery,
during which the clouded lens is removed and replaced with an artificial lens
Cornea
ü The cornea is the transparent part of the eye that covers the front portion of the eye. It covers the pupil (the
opening at the centre of the eye), iris (the coloured part of the eye), and anterior chamber (the fluid-filled
inside of the eye). The cornea’s main function is to refract, or bend, light. The cornea is responsible for
focusing most of the light that enters the eye.
ü Although the cornea is clear and seems to lack substance, it is a highly organized group of cells and proteins.
Unlike most tissues in the body, the cornea contains no blood vessels to nourish or protect it against
infection. Instead, the cornea receives its nourishment from the tears and aqueous humor (a fluid in the
anterior portion of the eye) that fills the chamber behind it. The cornea must remain transparent to refract
light properly, and the presence of even the tiniest blood vessels can interfere with this process. To see well,
all layers of the cornea must be free of any cloudy or opaque areas.
ü The cornea is comprised of five layers: the epithelium, Bowman’s layer, the stroma, Descemet’s membrane,
and the endothelium.
1. The first layer, the epithelium, is a layer of cells covering the cornea. It absorbs nutrients and oxygen from
tears and conveys it to the rest of the cornea. It contains free nerve endings. It also prevents foreign matter
from entering the eye
1. Bowman's Layer - Lying directly below the basement membrane of the epithelium is a transparent sheet of
tissue known as Bowman's layer. It is composed of strong layered protein fibers called collagen. Once
injured, Bowman's layer can form a scar as it heals. If these scars are large and centrally located, some
vision loss can occur.
2. Stroma - Beneath Bowman's layer is the stroma, which comprises about 90 percent of the cornea's
thickness. It consists primarily of water (78 percent) and collagen (16 percent), and does not contain any
blood vessels. Collagen gives the cornea its strength, elasticity, and form. The collagen's unique shape,
arrangement, and spacing are essential in producing the cornea's light-conducting transparency.
3. Descemet's Membrane - Under the stroma is Descemet's membrane, a thin but strong sheet of tissue that
serves as a protective barrier against infection and injuries. Descemet's membrane is composed of collagen
fibers (different from those of the stroma) and is made by the endothelial cells that lie below it. Descemet's
membrane is regenerated readily after injury.
4. Endothelium - The endothelium is the extremely thin, innermost layer of the cornea. Endothelial cells are
essential in keeping the cornea clear. Normally, fluid leaks slowly from inside the eye into the middle
corneal layer (stroma). The endothelium's primary task is to pump this excess fluid out of the stroma.
Without this pumping action, the stroma would swell with water, become hazy, and ultimately opaque. In a
healthy eye, a perfect balance is maintained between the fluid moving into the cornea and fluid being
pumped out of the cornea. Once endothelium cells are destroyed by disease or trauma, they are lost
forever. If too many endothelial cells are destroyed, corneal edema and blindness ensue, with corneal
transplantation the only available therapy.
Iris
• Iris, in anatomy, the pigmented muscular curtain near the front of the eye, between the cornea and the lens,
that is perforated by an opening called the pupil. The iris is located in front of the lens and ciliary body and
behind the cornea. It is bathed in front and behind by a fluid known as the aqueous humour
• The iris consists of two sheets of smooth muscle with contrary actions: dilation (expansion) and contraction
(constriction). These muscles control the size of the pupil and thus determine how much light reaches the
sensory tissue of the retina.
• The sphincter muscle of the iris is a circular muscle that constricts the pupil in bright light, whereas
the dilator muscle of the iris expands the opening when it contracts.
• The amount of pigment contained in the iris determines eye colour. When there is very little pigment, the
eye appears blue. With increased pigment, the shade becomes deep brown to black
• Inflammation of the iris is termed iritis or anterior uveitis, a condition that commonly has no determinable
cause. As a result of inflammation, the iris sticks to the lens or the cornea, blocking the normal flow of fluid
in the eye. Complications of iritis include secondary glaucoma and blindness; treatment usually involves
topical steroid eyedrops
Ocular Chamber
• The inside of the eye is divided into three sections called chambers
1. The anterior chamber (AC) is the aqueous humor-filled space inside the eye between the iris and
the cornea's innermost surface, the endothelium. Hyphema, anterior uveitis and glaucoma are three main
pathologies in this area. In hyphema, blood fills the anterior chamber as a result of a hemorrhage, most
commonly after a blunt eye injury. Anterior uveitis is an inflammatory process affecting the iris and ciliary
body, with resulting inflammatory signs in the anterior chamber. In glaucoma, blockage of the trabecular
meshwork prevents the normal outflow of aqueous humour, resulting in increased intraocular pressure,
progressive damage to the optic nerve head, and eventually blindness.The depth of the anterior chamber of
the eye varies between 1.5 and 4.0 mm, averaging 3.0 mm. It tends to become shallower at older age and
in eyes with hypermetropia (far sightedness). As depth decreases below 2.5 mm, the risk for angle closure
glaucoma increases.
2. The posterior chamber is a narrow space behind the peripheral part of the iris, and in front of
the suspensory ligament of the lens and the ciliary processes. The posterior chamber consists of small
space directly posterior to the iris but anterior to the lens. The posterior chamber is part of the anterior
segment and should not be confused with the vitreous chamber (in the posterior segment).Posterior
chamber is an important structure involved in production and circulation of aqueous humor. Aqueous
humor produced by the epithelium of the ciliary body is secreted into the posterior chamber, from which it
flows through the pupil to enter the anterior chamber.
3. Vitreous chamber: The vitreous chamber is between the lens and the back of the eyeThe back two-thirds of
the inner wall of the vitreous chamber is lined with a special layer of cells (the retina): millions of highly
sensitive nerve cells that convert light into nerve impulses.Fluid fills most of the inside of the eye. The
chambers in front of the lens (both the anterior and posterior chambers) are filled with a clear, watery fluid
called aqueous humor. The large space behind the lens (the vitreous chamber) contains a thick, gel-like fluid
called vitreous humor or vitreous gel. These two fluids press against the inside of the eyeball and help the
eyeball keep its shape.
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