al Ma. of Questions 8] [Teal Mo. of Printed Pages: 4 RolINo BP-402T/PY-402 (CBGS) B.Pharmacy IV Semester (PCI Scheme)! (Non-PCT Scheme) Examination, June 2022 Choice Based Grading System (CBGS) Medicinal Chemistry -1 Time: Tare Hours “Maximum Marks: 75 Nets) Atemptany Sve questions. fart a et at es 1) Allquesons cary equa mar bet Hr St i) te cae oF ay doubt or dispute the English version _quetion should bo wea si a oh re en ee Fe A asaerah site tm 1. a) Write the ststue and ures of ay one imidazoline heteroeyelicring containing dug, 3 fa co Petr Rete gen teu ee ‘oi cret FR ¥) Outline the importance of slubiliyin éugaction. 3 cae Far Rec ge ele eG 2) What is Phase biotansformation? Discuss any two oxidative reactions. ° Phase aeigrerian war 2 fied a atte af Re L ‘arava (CHO) ro bups:/wwwergpvontine.com » ° » 2 » 2 a ‘Write mechanism of ation of Opis Opioids 8 fer pa FRI Whats catecholamine? Menton any 0 important earotransmite catecholamines. 3 aremtere wen 27 fre! & neonates aerisere ar age A Discusshepatic and exru-hepatic metabolism ager ate ee a ore we BRAC ° Wire structure and uses of Neostigine. 3 FrahfReor A ae ed we FIT Wire the structure and MOA of Pilocarpine. 3 ahs A sete MOA PERT GivoeSARofbshadnerlodang ges Ouie the synthesis of Propranoel ta ea ia sanSihetac sti ahaa at) ‘What are Narcotic sntagonist? Give two examples with steverue 3 carbs a ar 82 eee 2 ener TTT APH Explain ain acid conugation in Phase -I metabolism 3 Phase 3ane A sete ere oN ETE Distinguish between Cholinergic agonist and antagonist “with example. White the syrhesis and MOA of pratopism ‘bromide. ° atin ihe ee heer Bs ek secu BR Re ass 2 istT aT MOA PARE ssragaT vata (C865) con hups:(/www.rgpvonline.com8 5, 9) White he synthesis of Phenyoin. 3 Remgeher dr deh GL 1) Define Biososterism with suitable examples, 3 cwcheeecor eo ae sero are atta ARR ©) Wie dountenmtss, MOA nde sedis. ecard, MOA, arent 6, 8) Define and clssify Sympsthomimetice agents with suitable examples. Disses SAR of Symphonies gens. Outi synthesis and wes of Subatamol. 3 Sympthomimets oh ee ee ere eae te ati a Sympathomimetis St SARS ae ail agent & deca ote gen A eta Ae ‘FPR 2) Defies infamatory gs Wrest andses of ary fo sch dig. Oui be syatess, MOA and UsesofToupoten 3 -Antinlarmator dags tn we Po Aft ice ae cc eae ee, Moa at oe atari 6) Dain nd casty NSAIDS wit angle Give he sic, MOA ofany od me ioceete athe A$ stn er, MOA Ba psartyvane (C808) Fro bups:/avww-repvontine.com 1a » 9 » ro) Define sedatives and hypnotics, Explain SAR of ‘enzndiaepines. Outline iesyheisof diazepam. 3 ares te eos a ear date SAR 2 cer! eed tt et Explain be cone of geomewicl isomerism, protein ‘ining and onzationof dro. Adda ot onthe role in ADME og 3 cafe eee, sb er se ne et sca ERT Tt ADEA IY HTS refomtatat Outline he snes. MOA and Uses of Chlorpromazine syochanige ° {ide MOA a ate pecs se at afer Discus the SAR of Anticonvulsants. Give the structs andes of Mathaba. 7 and SAR Ree Bra Neate A ET seoehe mer Write note on biosynthesis and eatabotism of acetone. : sRecreretorr dict ok eae a RL mp anav yon (CGS) bups:Avwwrgpvonline.com