USMLE Step 1 Clues

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1. Causes of heart block "LSD Loves Company" 9. TB Treatments "RESPI"

Lyme disease Rifampin
Shigella Ethambutol
Diptheria Streptomycin
Legionella Pyrozinamide
Chagas INH
2. Low Compliment Bugs "I AM HE" 10. SE of Statins Myositis
Influenza Hepatitis
Adenovirus ↑ Liver enzymes
Mycoplasma
11. Causes of Severe "STELS"
Hep B, C
Monocytosis Salmonella
EBV
TB
3. Causes of Reiter's "Crohn and I Saw Yersinia and EBV
Syndrome got Chlamydia" Listeria
Shigella Syphilis
Yersina
12. X-Linked Enzyme (Fabry and Lesh go Hunting for
Crohn's
Deficiencies Candy, Pie and Gum)
IBD
G6PD
Chlamydia
CGD (NADPH)
4. Drug induced Lupus "HIPPPE" Pyruvate DH
Hydralazine Fabry's
INH Hunter's
Procainamide Lesh-Nyhan
Penicillamine
13. Psammoma Bodies Papillary CA of Thyroid
Phenytoin
Serous Cystadenoma of ovary
Ethosuximide
Meningioma
5. Drugs that Blast BM "ABCV" Mesothelioma
AZT
14. Urease (+) Bugs "PPUNCHS"
Benzene
Proteus
Chloramphencol
Pseudomonas
Vinblastine
Ureaplasma urealyticum
6. Induce P-450 "BAG for CpR QTS" Norcardia
Barbiturates Cryptococcus neoformans
Alcohol H. pylori
Griseofulvin S. saprofiticus
Carbamazepine
15. Drugs that cause "BBAT"
Rifampin
Pulmonary Fibrosis Bleomycin
Quinidine
Busulfan
Tetracyclines
Amioderone
Spironolactones
Tocainide
7. Inhibit P-450 "I'D SMACK Quin"
16. IgA Nephropathies Henoch-Schoenlein Purpura (HSP)
INH
Berger's
Dapsone
Alport's
Sulfa Drugs
Macrolides 17. Massive Eosinophilia "NAACP"
Amiodarone Neoplasms
Cimetidine Allergies/Asthma
Ketoconazole Addison's
Quinolones Collagen Vascular Disease
Parasites
8. Low Compliment Nephrotic "PMS in Salt Lake City"
Syndromes PSGN 18. Drugs that cause "RIPS"
MPGN II Myositis Rifampin
SBE INH
Serum Sickness Prednisone
Lupus Statins
Cryoglobulineima.
19. Encapsulated Bacteria (Some Strange Killers Have Pretty 26. Rashes on Palms and Soles "TRiCKSSSS"
Nice Capsules) TSS (Toxic Shock)
Strep. Pneumo (gr. +) Rocky Mt. Spotted Fever
Salmonella Coxsackie A (Hand, Foot &
Klebsiella Mouth Dis.)
H. Flu B Kawasaki
Pseudomonas Scarlet Fever
Neisseria Syphilis
Citrobacter Staph. Scalded Skin
Streptobacillus moniliformis
20. Jones Criteria "J♥NES"
Polyarthritis (joints) 27. Neural Crest Cells "MOTEL PASS"
Carditis (♥) Melanocytes
Nodules subcutaneous Odontoblasts
Erythema marginatum Tracheal Cartilage
Sydenham Chorea Enterochromaffin Cells
Laryngeal Cartilage
21. Autoimmune Hemolytic "PαCS PAD"
Pseudounipolar/Parafollicular
Anemia PTU
All Ganglion/Adrenal Medulla
α-methyldopa
Schwann Cells
Cephalosporins
Spiral Membrane
Sulfa drugs
Penicillin 28. IgA Protease Bugs S. Pneumonia
Anti-malarials H. Influenza
Dapsone Neisseria
22. Pansystolic Murmurs "MTV" 29. Bacteria with Toxins that Pseudomonas
Mitral Regurg. inhibit EF-2 Diphtheria
Tricuspid Regurg.
30. 4 D's of Pellagra Dermatitis
Ventrical Septal Defect
Diarrhea
23. 9 LIve Vaccines Measles Dementia
Mumps Death
Rubella
31. MCC of UTI's #1 - E. coli
Oral Polio
#2 - Proteus
Rotavirus
#3 - Klebsiella
Small Pox
BCG 32. Gastroenteritis within 8 hrs (pre-formed toxin)
Yellow Fever of eating S. aureus (potato salads)
Varicella C. perfringens (holiday
turkey/ham)
24. Dihydrofolate Reductase Pyremethamine/Sulfadiazine
B. cereus (fried rice)
Inhibitors Trimethroprim/Sulfamethoxazole
Methotrexate 33. MCC of Airway Infection (sinusitis, otitis, bronchitis,
pneumonia)
25. Macrophages in Tissues Brain..........Microglia
#1 - S. pneumonia
Lung...........Type I Pneumo
#2 - H. influenza
Liver...........Kupffer
#3 - N. meningitides
Spleen........RES cells
Kidney........Mesangial 34. MCC of Newborn Meningitis "Baby BEL"
LN..............Dendritic Group B Strep
Skin............Langerhans E. coli
Bone...........Osteoclasts Listeria
CT..............Histiocytes 35. Herpes Virus I - oral
..................Giant cells II - genital
..................Epithelioid III - varicella zoster
IV - EBV
V - CMV
VI - Roseola
VII - Pityriasis rosea
VIII - Kaposi's
36. Amino Acid PKU - Phenylalanine hydroxylase deficiency, needed to make tyrosine, leads to a lack of Dopamine, Epi and
Deficiencies Norepi, melanin
Maple Syrup Urine Disease - deficiency in branched amino acids (Leu, Lys, Val), defective transport in the
kidneys
Cystinuria - Cystathione synthase deficiency; cysteine, ornithine, lysine and Arginine end up in urine, stones
37. Translocations 9:22 Philadelphia Chromosome (CML)
8:14 Burkitt's Lymphoma
14:18 Follicular Lymphoma
15:17 Promyelblastic leukemia
11:14 Mantle Cell Lymphoma
11:22 Ewing's Sarcoma
17:22 Neurofibromatosis